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Select item 104457301.

Separation of transcriptional repressor and activator functions in Drosophila HDAC3

Min Tang, Isabel Regadas, Sergey Belikov, Olga Shilkova, Lei Xu, Erik Wernersson, Xuewen Liu, Hongmei Wu, Magda Bienko, Mattias Mannervik

Development. 2023 Aug 1; 150(15): dev201548. Published online 2023 Aug 2. doi: 10.1242/dev.201548

PMCID:: PMC10445730

Abstract Article

Select item 103686962.

Nutritional stress-induced regulation of microtubule organization and mRNP transport by HDAC1 controlled α-tubulin acetylation

Frank Wippich, Vaishali, Marco L. Hennrich, Anne Ephrussi

Commun Biol. 2023; 6: 776. Published online 2023 Jul 25. doi: 10.1038/s42003-023-05138-w

PMCID:: PMC10368696

Abstract Article PDF–8.8M

Select item 101528013.

Deacetylase-dependent and -independent role of HDAC3 in cardiomyopathy

Jieyu Ren, Qun Zeng, Hongmei Wu, Xuewen Liu, Maria C. Guida, Wen Huang, Yiyuan Zhai, Junjie Li, Karen Ocorr, Rolf Bodmer, Min Tang

J Cell Physiol. Author manuscript; available in PMC 2023 May 2.

Published in final edited form as: J Cell Physiol. 2023 Mar; 238(3): 647–658. Published online 2023 Feb 6. doi: 10.1002/jcp.30957

PMCID:: PMC10152801

Abstract Article PDF–2.5M

Select item 101211744.

CBP and Gcn5 drive zygotic genome activation independently of their catalytic activity

Filippo Ciabrelli, Leily Rabbani, Francesco Cardamone, Fides Zenk, Eva Löser, Melanie A. Schächtle, Marina Mazina, Vincent Loubiere, Nicola Iovino

Sci Adv. 2023 Apr; 9(16): eadf2687. Published online 2023 Apr 21. doi: 10.1126/sciadv.adf2687

PMCID:: PMC10121174

Abstract Article PDF–1.6M

Select item 98941845.

Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila

Ting Miao, Jinoh Kim, Ping Kang, Hideji Fujiwara, Fong-Fu Hsu, Hua Bai

Proc Natl Acad Sci U S A. 2022 Dec 6; 119(49): e2212220119. Published online 2022 Dec 2. doi: 10.1073/pnas.2212220119

PMCID:: PMC9894184

Abstract Article PDF–3.8M

Select item 98902386.

Systematic identification and characterization of repressive domains in Drosophila transcription factors

Loni Klaus, Bernardo P de Almeida, Anna Vlasova, Filip Nemčko, Alexander Schleiffer, Katharina Bergauer, Lorena Hofbauer, Martina Rath, Alexander Stark

EMBO J. 2023 Feb; 42(3): e112100. Published online 2022 Dec 22. doi: 10.15252/embj.2022112100

PMCID:: PMC9890238

Abstract Article PDF–1.2M

Select item 96769847.

CBP-Mediated Acetylation of Importin α Mediates Calcium-Dependent Nucleocytoplasmic Transport of Selective Proteins in Drosophila Neurons

Jae Ho Cho, Min Gu Jo, Eun Seon Kim, Na Yoon Lee, Soon Ha Kim, Chang Geon Chung, Jeong Hyang Park, Sung Bae Lee

Mol Cells. 2022 Nov 30; 45(11): 855–867. Published online 2022 Sep 28. doi: 10.14348/molcells.2022.0104

PMCID:: PMC9676984

Abstract Article PDF–2.2M

Select item 93047078.

What we have learnt from Drosophila model organism: the coordination between insulin signaling pathway and tumor cells

Tang Weina, Li Ying, Wang Yiwen, Qiao Huan-huan

Heliyon. 2022 Jul; 8(7): e09957. Published online 2022 Jul 14. doi: 10.1016/j.heliyon.2022.e09957

PMCID:: PMC9304707

Abstract Article PDF–872K

Select item 86644869.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 865749210.

Regulation of Neural Stem Cell Competency and Commitment during Indirect Neurogenesis

Arjun Rajan, Cyrina M. Ostgaard, Cheng-Yu Lee

Int J Mol Sci. 2021 Dec; 22(23): 12871. Published online 2021 Nov 28. doi: 10.3390/ijms222312871

PMCID:: PMC8657492

Abstract Article PDF–1.5M

Select item 836357011.

Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex

Bat-Erdene Jugder, Layla Kamareddine, Paula I Watnick

Immunity. Author manuscript; available in PMC 2022 Aug 10.

Published in final edited form as: Immunity. 2021 Aug 10; 54(8): 1683–1697.e3. Published online 2021 Jun 8. doi: 10.1016/j.immuni.2021.05.017

PMCID:: PMC8363570

Abstract Article PDF–3.4M

Select item 782533212.

Epigenetic Regulation of ALS and CMT: A Lesson from Drosophila Models

Masamitsu Yamaguchi, Kentaro Omori, Satoshi Asada, Hideki Yoshida

Int J Mol Sci. 2021 Jan; 22(2): 491. Published online 2021 Jan 6. doi: 10.3390/ijms22020491

PMCID:: PMC7825332

Abstract Article PDF–400K

Select item 772844013.

Sequential activation of transcriptional repressors promotes progenitor commitment by silencing stem cell identity genes

Noemi Rives-Quinto, Hideyuki Komori, Cyrina M Ostgaard, Derek H Janssens, Shu Kondo, Qi Dai, Adrian W Moore, Cheng-Yu Lee

eLife. 2020; 9: e56187. Published online 2020 Nov 26. doi: 10.7554/eLife.56187

PMCID:: PMC7728440

Abstract Article PDF–9.4M

Select item 696157814.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 663925915.

The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes

Noelia Luna-Peláez, Rosana March-Díaz, María Ceballos-Chávez, Jose A. Guerrero-Martínez, Paolo Grazioli, Pablo García-Gutiérrez, Thomas Vaccari, Valentina Massa, Jose C. Reyes, Mario García-Domínguez

Cell Death Dis. 2019 Aug; 10(8): 548. Published online 2019 Jul 18. doi: 10.1038/s41419-019-1792-x

PMCID:: PMC6639259

Abstract Article PDF–3.2M

Select item 619940616.

A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach

Maxime W.C. Rousseaux, Gabriel E. Vázquez-Vélez, Ismael Al-Ramahi, Hyun-Hwan Jeong, Aleksandar Bajić, Jean-Pierre Revelli, Hui Ye, Emily T. Phan, Jennifer M. Deger, Alma M. Perez, Ji-Yoen Kim, Laura A. Lavery, Qikia Xu, Mamie Z. Li, Hyojin Kang, Jean J. Kim, Joshua M. Shulman, Thomas F. Westbrook, Stephen J. Elledge, Zhandong Liu, Juan Botas, Huda Y. Zoghbi

J Neurosci. 2018 Oct 24; 38(43): 9286–9301. doi: 10.1523/JNEUROSCI.0254-18.2018