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Select item 115729701.

tRNA modification enzyme-dependent redox homeostasis regulates synapse formation and memory

Kimberly R. Madhwani, Shanzeh Sayied, Carlson H. Ogata, Caley A. Hogan, Jenna M. Lentini, Moushami Mallik, Jennifer L. Dumouchel, Erik Storkebaum, Dragony Fu, Kate M. O’Connor-Giles

Proc Natl Acad Sci U S A. 2024 Nov 12; 121(46): e2317864121. Published online 2024 Nov 4. doi: 10.1073/pnas.2317864121

PMCID:: PMC11572970

Abstract Article PDF–7.4M

Select item 113919672.

Anti-aging and immunomodulatory role of caffeine in Drosophila larvae

Firzan Nainu, Sartini Sartini, Muhammad A. Bahar, Asbah Asbah, Reski A. Rosa, Mukarram Mudjahid, Muhammad F. As’ad, Nadila P. Latada

Narra J. 2024 Aug; 4(2): e818. Published online 2024 Jun 28. doi: 10.52225/narra.v4i2.818

PMCID:: PMC11391967

Abstract Article PDF–368K

Select item 113869553.

Glial ferritin maintains neural stem cells via transporting iron required for self-renewal in Drosophila

Zhixin Ma, Wenshu Wang, Xiaojing Yang, Menglong Rui, Su Wang

eLife. 2024; 13: RP93604. Published online 2024 Sep 10. doi: 10.7554/eLife.93604

PMCID:: PMC11386955

Abstract Article PDF–5.9M

Select item 112748214.

Pathological Defects in a Drosophila Model of Alzheimer’s Disease and Beneficial Effects of the Natural Product Lisosan G

Silvia Bongiorni, Elisabetta Catalani, Ivan Arisi, Francesca Lazzarini, Simona Del Quondam, Kashi Brunetti, Davide Cervia, Giorgio Prantera

Biomolecules. 2024 Jul; 14(7): 855. Published online 2024 Jul 15. doi: 10.3390/biom14070855

PMCID:: PMC11274821

Abstract Article PDF–2.6M

Select item 112012535.

Intergenerational Impact of Parental Zinc Deficiency on Metabolic and Redox Outcomes in Drosophila melanogaster

Kamaldeen Olalekan Sanusi, Kasimu Ghandi Ibrahim, Murtala Bello Abubakar, Tijjani Salihu Shinkafi, Aminu Ishaka, Mustapha Umar Imam

Biology (Basel) 2024 Jun; 13(6): 401. Published online 2024 Jun 1. doi: 10.3390/biology13060401

PMCID:: PMC11201253

Abstract Article PDF–1.7M

Select item 111928396.

Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models

Wing Hei Au, Leonor Miller-Fleming, Alvaro Sanchez-Martinez, James AK Lee, Madeleine J Twyning, Hiran A Prag, Laura Raik, Scott P Allen, Pamela J Shaw, Laura Ferraiuolo, Heather Mortiboys, Alexander J Whitworth

Life Sci Alliance. 2024 Sep; 7(9): e202402853. Published online 2024 Jun 21. doi: 10.26508/lsa.202402853

PMCID:: PMC11192839

Abstract Article PDF–3.3M

Select item 111254077.

Curcumin-mediated alleviation of dextran-induced leaky gut in Drosophila melanogaster

Mufliha Khaerani, Rizkya Chaeratunnisa, Annisa Salsabila, Asbah Asbah, Rangga M. Asri, Akiko Shiratsuchi, Firzan Nainu

Narra J. 2024 Apr; 4(1): e743. Published online 2024 Apr 22. doi: 10.52225/narra.v4i1.743

PMCID:: PMC11125407

Abstract Article PDF–704K

Select item 111244578.

Box–Behnken Design-Based Optimization of Phytochemical Extraction from Diplazium esculentum (Retz.) Sw. Associated with Its Antioxidant and Anti-Alzheimer’s Properties

Sirawit Kongsung, Woorawee Inthachat, Boonrat Chantong, Uthaiwan Suttisansanee, Nattira On-Nom, Chaowanee Chupeerach, Sirinapa Thangsiri, Pornsiri Pitchakarn, Piya Temviriyanukul

Molecules. 2024 May; 29(10): 2204. Published online 2024 May 8. doi: 10.3390/molecules29102204

PMCID:: PMC11124457

Abstract Article PDF–3.8M

Select item 111110759.

Destructive effects of UVC radiation on Drosophila melanogaster: Mortality, fertility, mutations, and molecular mechanisms

Mohamed Lotfy, Aalaa Khattab, Mohammed Shata, Ahmad Alhasbani, Abdulla Almesmari, Saeed Alsaeedi, Saeed Alyassi, Biduth Kundu

PLoS One. 2024; 19(5): e0303115. Published online 2024 May 22. doi: 10.1371/journal.pone.0303115

PMCID:: PMC11111075

Abstract Article PDF–1.3M

Select item 1107987510.

Evaluating the Impact of Vitamin D₃ on NF-κB and JAK/STAT Signaling Pathways in Drosophila melanogaster

Widya Hardiyanti, Yulia Yusrini Djabir, Dewita Fatiah, Muhammad Rasul Pratama, Tenri Zulfa Ayu Dwi Putri, Rizkya Chaeratunnisa, Nadila Pratiwi Latada, Mukarram Mudjahid, Rangga Meidianto Asri, Firzan Nainu

ACS Omega. 2024 May 7; 9(18): 20135–20141. Published online 2024 Apr 25. doi: 10.1021/acsomega.4c00134

PMCID:: PMC11079875

Abstract Article PDF–1.8M

Select item 1103542611.

Dietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue

Meng Liu, Li He

Cell Mol Life Sci. 2024 Dec; 81(1): 190. Published online 2024 Apr 22. doi: 10.1007/s00018-024-05226-y

PMCID:: PMC11035426

Abstract Article PDF–5.8M

Select item 1102102812.

Gene expression variation underlying tissue-specific responses to copper stress in Drosophila melanogaster

Elizabeth R Everman, Stuart J Macdonald

G3 (Bethesda) 2024 Mar; 14(3): jkae015. Published online 2024 Jan 23. doi: 10.1093/g3journal/jkae015

PMCID:: PMC11021028

Abstract Article PDF–716K

Select item 1101499213.

Mitochondrial fusion and altered beta-oxidation drive muscle wasting in a Drosophila cachexia model

Callum Dark, Nashia Ali, Sofya Golenkina, Vaibhav Dhyani, Ronnie Blazev, Benjamin L Parker, Kate T Murphy, Gordon S Lynch, Tarosi Senapati, S Sean Millard, Sarah M Judge, Andrew R Judge, Lopamudra Giri, Sarah M Russell, Louise Y Cheng

EMBO Rep. 2024 Apr; 25(4): 1835–1858. Published online 2024 Mar 1. doi: 10.1038/s44319-024-00102-z

PMCID:: PMC11014992

Abstract Article PDF–6.2M

Select item 1094493114.

Invertebrate genetic models of amyotrophic lateral sclerosis

LiJun Zhou, RenShi Xu

Front Mol Neurosci. 2024; 17: 1328578. Published online 2024 Mar 4. doi: 10.3389/fnmol.2024.1328578

PMCID:: PMC10944931

Abstract Article PDF–2.0M

Select item 1093595415.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 1092944916.

Drosophila melanogaster Sting mediates Coxiella burnetii infection by reducing accumulation of reactive oxygen species

Rosa M. Guzman, Nathan G. Savolainen, Olivia M. Hayden, Miyoung Lee, Chelsea A. Osbron, Ziying Liu, Hong Yang, Dana K. Shaw, Anders Omsland, Alan G. Goodman

Infect Immun. 2024 Mar; 92(3): e00560-22. Published online 2024 Feb 16. doi: 10.1128/iai.00560-22

PMCID:: PMC10929449

Abstract Article PDF–2.2M

Select item 1089197517.

Exposure to the Natural Compound Climacostol Induces Cell Damage and Oxidative Stress in the Fruit Fly Drosophila melanogaster

Elisabetta Catalani, Kashi Brunetti, Simona Del Quondam, Silvia Bongiorni, Simona Picchietti, Anna Maria Fausto, Gabriele Lupidi, Enrico Marcantoni, Cristiana Perrotta, Gabriele Achille, Federico Buonanno, Claudio Ortenzi, Davide Cervia

Toxics. 2024 Feb; 12(2): 102. Published online 2024 Jan 24. doi: 10.3390/toxics12020102