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Select item 111221211.

Transcriptomic Insights into Host Metabolism and Immunity Changes after Parasitization by Leptopilina myrica

Junwei Zhang, Jieyu Shan, Wenqi Shi, Ting Feng, Yifeng Sheng, Zixuan Xu, Zhi Dong, Jianhua Huang, Jiani Chen

Insects. 2024 May; 15(5): 352. Published online 2024 May 14. doi: 10.3390/insects15050352

PMCID:: PMC11122121

Abstract Article PDF–2.4M

Select item 104348972.

The genetic basis of variation in immune defense against Lysinibacillus fusiformis infection in Drosophila melanogaster

Brittny R. Smith, Kistie B. Patch, Anjali Gupta, Emma M. Knoles, Robert L. Unckless

PLoS Pathog. 2023 Aug; 19(8): e1010934. Published online 2023 Aug 7. doi: 10.1371/journal.ppat.1010934

PMCID:: PMC10434897

Abstract Article PDF–2.5M

Select item 104340043.

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

Microbiol Spectr. 2023 Jul-Aug; 11(4): e00777-23. Published online 2023 Jun 1. doi: 10.1128/spectrum.00777-23

PMCID:: PMC10434004

Abstract Article PDF–1.7M

Select item 103177844.

Interactions with ectoparasitic mites induce host metabolic and immune responses in flies at the expense of reproduction-associated factors

Joshua B. Benoit, Joy Bose, Samuel T. Bailey, Michal Polak

Parasitology. 2020 Sep; 147(11): 1196–1205. Published online 2020 Jun 5. doi: 10.1017/S0031182020000918

PMCID:: PMC10317784

Abstract Article PDF–602K

Select item 101633245.

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

Mark A. Hanson, Bruno Lemaitre

Dis Model Mech. 2023 Apr 1; 16(4): dmm049965. Published online 2023 Apr 26. doi: 10.1242/dmm.049965

PMCID:: PMC10163324

Abstract Article

Select item 101057366.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 100792277.

Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes

Hamadoun Touré, Lee Ann Galindo, Marion Lagune, Simon Glatigny, Robert M. Waterhouse, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

PLoS Pathog. 2023 Mar; 19(3): e1011257. Published online 2023 Mar 27. doi: 10.1371/journal.ppat.1011257

PMCID:: PMC10079227

Abstract Article PDF–2.1M

Select item 100523498.

Adult and Larval Tracheal Systems Exhibit Different Molecular Architectures in Drosophila

Judith Bossen, Ruben Prange, Jan-Philip Kühle, Sven Künzel, Xiao Niu, Jörg U. Hammel, Laura Krieger, Mirjam Knop, Birte Ehrhardt, Karin Uliczka, Susanne Krauss-Etschmann, Thomas Roeder

Int J Mol Sci. 2023 Mar; 24(6): 5628. Published online 2023 Mar 15. doi: 10.3390/ijms24065628

PMCID:: PMC10052349

Abstract Article PDF–5.6M

Select item 98275489.

The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins

Rui Xu, Yanyan Lou, Antonin Tidu, Philippe Bulet, Thorsten Heinekamp, Franck Martin, Axel Brakhage, Zi Li, Samuel Liégeois, Dominique Ferrandon

EMBO Rep. 2023 Jan; 24(1): e56036. Published online 2022 Nov 2. doi: 10.15252/embr.202256036

PMCID:: PMC9827548

Abstract Article PDF–3.4M

Select item 967144310.

Trans-regulatory changes underpin the evolution of the Drosophila immune response

Shuai Dominique Ding, Alexandre B. Leitão, Jonathan P. Day, Ramesh Arunkumar, Morgan Phillips, Shuyu Olivia Zhou, Francis M. Jiggins

PLoS Genet. 2022 Nov; 18(11): e1010453. Published online 2022 Nov 7. doi: 10.1371/journal.pgen.1010453

PMCID:: PMC9671443

Abstract Article PDF–2.2M

Select item 963564411.

Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway

Rujuta Deshpande, Byoungchun Lee, Savraj S Grewal

G3 (Bethesda) 2022 Nov; 12(11): jkac163. Published online 2022 Jul 4. doi: 10.1093/g3journal/jkac163

PMCID:: PMC9635644

Abstract Article PDF–2.2M

Select item 920864812.

microRNA-252 and FoxO repress inflammaging by a dual inhibitory mechanism on Dawdle-mediated TGF-β pathway in Drosophila

Xiaofen Wu, Kongyan Niu, Xiaofan Wang, Jing Zhao, Han Wang, Dean Li, Hui Wang, Ting Miao, Yun Yang, Huanhuan Ma, Yaoyang Zhang, Lei Pan, Rui Liu, Hua Bai, Nan Liu

Genetics. 2022 Mar; 220(3): iyab234. Published online 2021 Dec 21. doi: 10.1093/genetics/iyab234

PMCID:: PMC9208648

Abstract Article PDF–1.5M

Select item 914746313.

Meta-Analysis of Immune Induced Gene Expression Changes in Diverse Drosophila melanogaster Innate Immune Responses

Ashley L. Waring, Joshua Hill, Brooke M. Allen, Nicholas M. Bretz, Nguyen Le, Pooja Kr, Dakota Fuss, Nathan T. Mortimer

Insects. 2022 May; 13(5): 490. Published online 2022 May 23. doi: 10.3390/insects13050490

PMCID:: PMC9147463

Abstract Article PDF–1.6M

Select item 834161214.

First transcriptome profiling of D. melanogaster after development in a deep underground low radiation background laboratory

Mikhail Zarubin, Albert Gangapshev, Yuri Gavriljuk, Vladimir Kazalov, Elena Kravchenko

PLoS One. 2021; 16(8): e0255066. Published online 2021 Aug 5. doi: 10.1371/journal.pone.0255066

PMCID:: PMC8341612

Abstract Article PDF–1.5M

Select item 808422915.

Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii

Florent Masson, Samuel Rommelaere, Alice Marra, Fanny Schüpfer, Bruno Lemaitre

PLoS One. 2021; 16(4): e0250524. Published online 2021 Apr 29. doi: 10.1371/journal.pone.0250524

PMCID:: PMC8084229

Abstract Article PDF–1.5M

Select item 776824116.

Survival Following Traumatic Brain Injury in Drosophila Is Increased by Heterozygosity for a Mutation of the NF-κB Innate Immune Response Transcription Factor Relish

Laura C. Swanson, Edna A. Trujillo, Gene H. Thiede, Rebeccah J. Katzenberger, Evgenia Shishkova, Joshua J. Coon, Barry Ganetzky, David A. Wassarman

Genetics. 2020 Dec; 216(4): 1117–1136. Published online 2020 Oct 27. doi: 10.1534/genetics.120.303776

PMCID:: PMC7768241

Abstract Article PDF–1.8M

Select item 772113417.

Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function

Brittany A. Martínez, Rosalie G. Hoyle, Scott Yeudall, Mitchell E. Granade, Thurl E. Harris, J. David Castle, Norbert Leitinger, Michelle L. Bland

PLoS Genet. 2020 Nov; 16(11): e1009192. Published online 2020 Nov 23. doi: 10.1371/journal.pgen.1009192

PMCID:: PMC7721134

Abstract Article PDF–3.4M

Select item 755019218.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 752622619.

Integrated analysis of the aging brain transcriptome and proteome in tauopathy

Carl Grant Mangleburg, Timothy Wu, Hari K. Yalamanchili, Caiwei Guo, Yi-Chen Hsieh, Duc M. Duong, Eric B. Dammer, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu, Joshua M. Shulman

Mol Neurodegener. 2020; 15: 56. Published online 2020 Sep 29. doi: 10.1186/s13024-020-00405-4

PMCID:: PMC7526226

Abstract Article PDF–1.4M

Select item 710142820.

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

Patricia Deng, Anzer Khan, Dionna Jacobson, Nagraj Sambrani, Leeanne McGurk, Xianghua Li, Aswathy Jayasree, Jan Hejatko, Galit Shohat-Ophir, Mary A. O’Connell, Jin Billy Li, Liam P. Keegan

Nat Commun. 2020; 11: 1580. Published online 2020 Mar 27. doi: 10.1038/s41467-020-15435-1

PMCID:: PMC7101428

Abstract Article PDF–1.6M

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