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Select item 110210271.

A Drosophila screen identifies a role for histone methylation in ER stress preconditioning

Katie G Owings, Clement Y Chow

G3 (Bethesda) 2024 Feb; 14(2): jkad265. Published online 2023 Dec 14. doi: 10.1093/g3journal/jkad265

PMCID:: PMC11021027

Abstract Article PDF–738K

Select item 109455082.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 109454003.

When the microbiome shapes the host: immune evolution implications for infectious disease

Mark A. Hanson

Philos Trans R Soc Lond B Biol Sci. May 6, 2024; 379(1901): 20230061. Published online March 18, 2024. doi: 10.1098/rstb.2023.0061

PMCID:: PMC10945400

Abstract Article PDF–667K

Select item 109359544.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 107871065.

Branched‐Chain Amino Acid Accumulation Fuels the Senescence‐Associated Secretory Phenotype

Yaosi Liang, Christopher Pan, Tao Yin, Lu Wang, Xia Gao, Ergang Wang, Holly Quang, De Huang, Lianmei Tan, Kun Xiang, Yu Wang, Peter B. Alexander, Qi‐Jing Li, Tso‐Pang Yao, Zhao Zhang, Xiao‐Fan Wang

Adv Sci (Weinh) 2024 Jan; 11(2): 2303489. Published online 2023 Nov 15. doi: 10.1002/advs.202303489

PMCID:: PMC10787106

Abstract Article PDF–5.0M

Select item 106974166.

Systematic assessment of transcriptomic and metabolic reprogramming by blue light exposure coupled with aging

Jia Huang, Fan Zhou, Huanchan Zhou, Xiaoqi Zheng, Zhengyi Huo, Meng Yang, Zihe Xu, Runzhou Liu, Luoluo Wang, Xiaoyun Wang

PNAS Nexus. 2023 Dec; 2(12): pgad390. Published online 2023 Dec 5. doi: 10.1093/pnasnexus/pgad390

PMCID:: PMC10697416

Abstract Article PDF–1.3M

Select item 105372667.

Viruses in Laboratory Drosophila and Their Impact on Host Gene Expression

Oumie Kuyateh, Darren J. Obbard

Viruses. 2023 Sep; 15(9): 1849. Published online 2023 Aug 31. doi: 10.3390/v15091849

PMCID:: PMC10537266

Abstract Article PDF–3.5M

Select item 103177848.

Interactions with ectoparasitic mites induce host metabolic and immune responses in flies at the expense of reproduction-associated factors

Joshua B. Benoit, Joy Bose, Samuel T. Bailey, Michal Polak

Parasitology. 2020 Sep; 147(11): 1196–1205. Published online 2020 Jun 5. doi: 10.1017/S0031182020000918

PMCID:: PMC10317784

Abstract Article PDF–602K

Select item 102809289.

Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS

Wenkai Yue, Xue Deng, Zhao Wang, Mingsheng Jiang, Rirong Hu, Yongjia Duan, Qiangqiang Wang, Jihong Cui, Yanshan Fang

Immun Ageing. 2023; 20: 27. Published online 2023 Jun 20. doi: 10.1186/s12979-023-00354-8

PMCID:: PMC10280928

Abstract Article PDF–9.0M

Select item 1026415710.

Downregulation of Hsp90 and the Antimicrobial Peptide Mtk Suppresses Poly(GR)-Induced Neurotoxicity in C9ORF72-ALS/FTD

Soojin Lee, Yong-Woo Jun, Gabriel R. Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill Moore, Gopinath Krishnan, Bryan Ruiz-Juarez, Manuel Santana, Marine Pons, Neal Silverman, Zhiping Weng, Justin Ichida, Fen-Biao Gao

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1381–1390.e6. Published online 2023 Mar 16. doi: 10.1016/j.neuron.2023.02.029

PMCID:: PMC10264157

Abstract Article PDF–1.9M

Select item 1016332411.

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

Mark A. Hanson, Bruno Lemaitre

Dis Model Mech. 2023 Apr 1; 16(4): dmm049965. Published online 2023 Apr 26. doi: 10.1242/dmm.049965

PMCID:: PMC10163324

Abstract Article

Select item 1010573612.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 1008971313.

Natural genetic variation in a dopamine receptor is associated with variation in female fertility in Drosophila melanogaster

Richard F. Lyman, Rachel A. Lyman, Akihiko Yamamoto, Wen Huang, Susan T. Harbison, Shanshan Zhou, Robert R. H. Anholt, Trudy F. C. Mackay

Proc Biol Sci. April 12, 2023; 290(1996): 20230375. Published online April 12, 2023. doi: 10.1098/rspb.2023.0375

PMCID:: PMC10089713

Abstract Article PDF–1.0M

Select item 1006635214.

Single Cell Analysis of the Fate of Injected Oncogenic RasV12 Cells in Adult Wild Type Drosophila

Di Chen, Xiao Lan, Xiaoming Huang, Jieqing Huang, Xiaojing Zhou, Zhichao Miao, Yuting Ma, Akira Goto, Shanming Ji, Jules A. Hoffmann

J Innate Immun. 2023 Jan-Dec; 15(1): 442–467. Published online 2023 Mar 30. doi: 10.1159/000529096

PMCID:: PMC10066352

Abstract Article PDF–6.1M

Select item 1005994215.

Unraveling the Role of Antimicrobial Peptides in Insects

Sylwia Stączek, Małgorzata Cytryńska, Agnieszka Zdybicka-Barabas

Int J Mol Sci. 2023 Mar; 24(6): 5753. Published online 2023 Mar 17. doi: 10.3390/ijms24065753

PMCID:: PMC10059942

Abstract Article PDF–1.8M

Select item 1005395816.

Intestinal Immune Deficiency and Juvenile Hormone Signaling Mediate a Metabolic Trade-off in Adult Drosophila Females

Gavriella Shianiou, Savvas Teloni, Yiorgos Apidianakis

Metabolites. 2023 Mar; 13(3): 340. Published online 2023 Feb 24. doi: 10.3390/metabo13030340

PMCID:: PMC10053958

Abstract Article PDF–5.2M

Select item 1005234917.

Adult and Larval Tracheal Systems Exhibit Different Molecular Architectures in Drosophila

Judith Bossen, Ruben Prange, Jan-Philip Kühle, Sven Künzel, Xiao Niu, Jörg U. Hammel, Laura Krieger, Mirjam Knop, Birte Ehrhardt, Karin Uliczka, Susanne Krauss-Etschmann, Thomas Roeder

Int J Mol Sci. 2023 Mar; 24(6): 5628. Published online 2023 Mar 15. doi: 10.3390/ijms24065628

PMCID:: PMC10052349

Abstract Article PDF–5.6M

Select item 976172818.

Heightened immune surveillance in Drosophila melanogaster populations selected for faster development and extended longevity

Nidhi Krishna Shrivastava, Namita Chauhan, Mallikarjun N. Shakarad

Heliyon. 2022 Dec; 8(12): e12090. Published online 2022 Dec 5. doi: 10.1016/j.heliyon.2022.e12090

PMCID:: PMC9761728

Abstract Article PDF–1.5M

Select item 972673319.

Hemocytes and fat body cells, the only professional immune cell types in Drosophila, show strikingly different responses to systemic infections

Vaibhvi Vaibhvi, Sven Künzel, Thomas Roeder

Front Immunol. 2022; 13: 1040510. Published online 2022 Nov 23. doi: 10.3389/fimmu.2022.1040510

PMCID:: PMC9726733

Abstract Article PDF–15M

Select item 966736320.

Ageing leads to reduced specificity of antimicrobial peptide responses in Drosophila melanogaster

Biswajit Shit, Arun Prakash, Saubhik Sarkar, Pedro F. Vale, Imroze Khan

Proc Biol Sci. November 30, 2022; 289(1987): 20221642. Published online November 16, 2022. doi: 10.1098/rspb.2022.1642

PMCID:: PMC9667363

Abstract Article PDF–1.2M

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