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Select item 109489341.

A genetic screen to uncover mechanisms underlying lipid transfer protein function at membrane contact sites

Shirish Mishra, Vaishnavi Manohar, Shabnam Chandel, Tejaswini Manoj, Subhodeep Bhattacharya, Nidhi Hegde, Vaisaly R Nath, Harini Krishnan, Corinne Wendling, Thomas Di Mattia, Arthur Martinet, Prasanth Chimata, Fabien Alpy, Padinjat Raghu

Life Sci Alliance. 2024 Jun; 7(6): e202302525. Published online 2024 Mar 18. doi: 10.26508/lsa.202302525

PMCID:: PMC10948934

Abstract Article PDF–2.6M

Select item 103542742.

Disruption in the regulation of casein kinase 2 in circadian rhythm leads to pathological states: cancer, diabetes and neurodegenerative disorders

Md. Zubbair Malik, Mohammed Dashti, Yasmin Fatima, Arshad Channanath, Sumi Elsa John, R. K. Brojen Singh, Fahd Al-Mulla, Thangavel Alphonse Thanaraj

Front Mol Neurosci. 2023; 16: 1217992. Published online 2023 Jul 5. doi: 10.3389/fnmol.2023.1217992

PMCID:: PMC10354274

Abstract Article PDF–21M

Select item 101057363.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 94511594.

Variant Polycomb complexes in Drosophila consistent with ancient functional diversity

Hyuckjoon Kang, Janel R. Cabrera, Barry M. Zee, Heather A. Kang, Jenny Marie Jobe, Maeve B. Hegarty, Aurelie E. Barry, Alexander Glotov, Yuri B. Schwartz, Mitzi I. Kuroda

Sci Adv. 2022 Sep; 8(36): eadd0103. Published online 2022 Sep 7. doi: 10.1126/sciadv.add0103

PMCID:: PMC9451159

Abstract Article PDF–1.3M

Select item 91364915.

Phosphorylation of Yun is required for stem cell proliferation and tumorigenesis

Xuejing Ren, Hang Zhao, Lin Shi, Zhengran Li, Ruiyan Kong, Rui Ma, Lemei Jia, Shan Lu, Jian‐Hua Wang, Meng‐qiu Dong, Yingchun Wang, Zhouhua Li

Cell Prolif. 2022 May; 55(5): e13230. Published online 2022 Apr 18. doi: 10.1111/cpr.13230

PMCID:: PMC9136491

Abstract Article PDF–12M

Select item 87140736.

CK1α protects WAVE from degradation to regulate cell shape and motility in the immune response

Alexander Hirschhäuser, Marianne van Cann, Sven Bogdan

J Cell Sci. 2021 Dec 1; 134(23): jcs258891. Published online 2021 Dec 9. doi: 10.1242/jcs.258891

PMCID:: PMC8714073

Abstract Article

Select item 86644867.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 81840098.

The Exon Junction Complex and intron removal prevent re-splicing of mRNA

Brian Joseph, Eric C. Lai

PLoS Genet. 2021 May; 17(5): e1009563. Published online 2021 May 25. doi: 10.1371/journal.pgen.1009563

PMCID:: PMC8184009

Abstract Article PDF–2.4M

Select item 78742079.

Stellate Genes and the piRNA Pathway in Speciation and Reproductive Isolation of Drosophila melanogaster

Vladimir E. Adashev, Alexei A. Kotov, Sergei S. Bazylev, Aleksei S. Shatskikh, Alexei A. Aravin, Ludmila V. Olenina

Front Genet. 2020; 11: 610665. Published online 2021 Jan 22. doi: 10.3389/fgene.2020.610665

PMCID:: PMC7874207

Abstract Article PDF–2.9M

Select item 755019210.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 702582211.

Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability

Tamsin J Samuels, Aino I Järvelin, David Ish-Horowicz, Ilan Davis

eLife. 2020; 9: e51529. Published online 2020 Jan 14. doi: 10.7554/eLife.51529

PMCID:: PMC7025822

Abstract Article PDF–3.4M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 694504213.

A Genetic Screen for Genes That Impact Peroxisomes in Drosophila Identifies Candidate Genes for Human Disease

Hillary K. Graves, Sharayu Jangam, Kai Li Tan, Antonella Pignata, Elaine S. Seto, Shinya Yamamoto, Michael F. Wangler

G3 (Bethesda) 2020 Jan; 10(1): 69–77. Published online 2019 Nov 25. doi: 10.1534/g3.119.400803

PMCID:: PMC6945042

Abstract Article PDF–2.2M

Select item 684748714.

Phosphorylation of Drosophila CENP-A on serine 20 regulates protein turn-over and centromere-specific loading

Anming Huang, Leopold Kremser, Fabian Schuler, Doris Wilflingseder, Herbert Lindner, Stephan Geley, Alexandra Lusser

Nucleic Acids Res. 2019 Nov 18; 47(20): 10754–10770. Published online 2019 Sep 19. doi: 10.1093/nar/gkz809

PMCID:: PMC6847487

Abstract Article PDF–20M

Select item 675805415.

Genome-Wide Expression Analysis in DrosophilaReveals Genes Controlling Circadian Behavior

M. Fernanda Ceriani, John B. Hogenesch, Marcelo Yanovsky, Satchidananda Panda, Martin Straume, Steve A. Kay

J Neurosci. 2002 Nov 1; 22(21): 9305–9319. doi: 10.1523/JNEUROSCI.22-21-09305.2002

PMCID:: PMC6758054

Abstract Article PDF–406K

Select item 654006316.

A Symphony of Signals: Intercellular and Intracellular Signaling Mechanisms Underlying Circadian Timekeeping in Mice and Flies

Sara Hegazi, Christopher Lowden, Julian Rios Garcia, Arthur H. Cheng, Karl Obrietan, Joel D. Levine, Hai-Ying Mary Cheng

Int J Mol Sci. 2019 May; 20(9): 2363. Published online 2019 May 13. doi: 10.3390/ijms20092363

PMCID:: PMC6540063

Abstract Article PDF–1.1M

Select item 645110717.

Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila

Mengqi Lv, Yixiang Yao, Fudong Li, Ling Xu, Lingna Yang, Qingguo Gong, Yong-Zhen Xu, Yunyu Shi, Yu-Jie Fan, Yajun Tang

Nucleic Acids Res. 2019 Apr 8; 47(6): 3142–3157. Published online 2019 Jan 15. doi: 10.1093/nar/gky1308

PMCID:: PMC6451107

Abstract Article PDF–6.4M

Select item 607860418.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 582743419.

The protein kinase CK2 substrate Jabba modulates lipid metabolism during Drosophila oogenesis

Emily A. McMillan, Sheila M. Longo, Michael D. Smith, Sarah Broskin, Baicheng Lin, Nisha K. Singh, Todd I. Strochlic

J Biol Chem. 2018 Feb 23; 293(8): 2990–3002. Published online 2018 Jan 11. doi: 10.1074/jbc.M117.814657

PMCID:: PMC5827434

Abstract Article PDF–2.6M

Select item 570780520.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

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