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Items: 1 to 20 of 33

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology
Kristine E. Zengeler, Daniel A. Shapiro, Katherine R. Bruch, Catherine R. Lammert, Hannah Ennerfelt, John R. Lukens
Brain Behav Immun. Author manuscript; available in PMC 2023 Jun 26.
Published in final edited form as: Brain Behav Immun. 2023 Feb; 108: 80–97. Published online 2022 Nov 4. doi: 10.1016/j.bbi.2022.10.024
PMCID:
PMC10291741
AbstractArticlePDF–2.7M
3.
Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells
Aydan Bulut-Karslioglu, Hu Jin, Yun-Kyo Kim, Brandon Cho, Marcela Guzman-Ayala, Andrew J. K. Williamson, Miroslav Hejna, Maximilian Stötzel, Anthony D. Whetton, Jun S. Song, Miguel Ramalho-Santos
Nat Commun. 2021; 12: 4859. Published online 2021 Aug 11. doi: 10.1038/s41467-021-25088-3
PMCID:
PMC8357957
AbstractArticlePDF–4.1M
4.
TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation
Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam
eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873
PMCID:
PMC7968925
AbstractArticlePDF–4.0M
5.
Chromatin Regulator, CHD1, Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer
Di Zhao, Li Cai, Xin Lu, Xin Liang, Jiexi Li, Peiwen Chen, Michael Ittmann, Xiaoying Shang, Shan Jiang, Haoyan Li, Chenling Meng, Ivonne Flores, Jian H. Song, James W Horner, Zhengdao Lan, Chang-Jiun Wu, Jun Li, Qing Chang, Ko-Chien Chen, Guocan Wang, Pingna Deng, Denise J. Spring, Y. Alan Wang, Ronald A. DePinho
Cancer Discov. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: Cancer Discov. 2020 Sep; 10(9): 1374–1387. Published online 2020 May 8. doi: 10.1158/2159-8290.CD-19-1352
PMCID:
PMC7483306
AbstractArticlePDF–1.3M
6.
Loss-of-Function Variants in PPP1R12A: From Isolated Sex Reversal to Holoprosencephaly Spectrum and Urogenital Malformations
Joel J. Hughes, Ebba Alkhunaizi, Paul Kruszka, Louise C. Pyle, Dorothy K. Grange, Seth I. Berger, Katelyn K. Payne, Diane Masser-Frye, Tommy Hu, Michelle R. Christie, Nancy J. Clegg, Joshua L. Everson, Ariel F. Martinez, Laurence E. Walsh, Emma Bedoukian, Marilyn C. Jones, Catharine Jean Harris, Korbinian M. Riedhammer, Daniela Choukair, Patricia Y. Fechner, Meilan M. Rutter, Sophia B. Hufnagel, Maian Roifman, Gad B. Kletter, Emmanuele Delot, Eric Vilain, Robert J. Lipinski, Chad M. Vezina, Maximilian Muenke, David Chitayat
Am J Hum Genet. 2020 Jan 2; 106(1): 121–128. Published online 2019 Dec 26. doi: 10.1016/j.ajhg.2019.12.004
PMCID:
PMC7042489
AbstractArticlePDF–1.1M
7.
CHD1 loss alters AR binding at lineage-specific enhancers and modulates distinct transcriptional programs to drive prostate tumorigenesis
Michael A. Augello, Deli Liu, Lesa D. Deonarine, Brian D. Robinson, Dennis Huang, Suzan Stelloo, Mirjam Blattner, Ashley S. Doane, Elissa W.P. Wong, Yu Chen, Mark A. Rubin, Himisha Beltran, Olivier Elemento, Andries M. Bergman, Wilbert Zwart, Andrea Sboner, Noah Dephoure, Christopher E. Barbieri
Cancer Cell. Author manuscript; available in PMC 2020 Apr 15.
Published in final edited form as: Cancer Cell. 2019 Apr 15; 35(4): 603–617.e8. Published online 2019 Mar 28. doi: 10.1016/j.ccell.2019.03.001
Correction in:
Cancer Cell. 2019 May 13; 35(5): 817–819.
PMCID:
PMC6467783
AbstractArticlePDF–3.2M
8.
Role for Chromatin Remodeling Factor Chd1 in Learning and Memory
Ines Schoberleitner, Anna Mutti, Anupam Sah, Alexandra Wille, Francisco Gimeno-Valiente, Paolo Piatti, Maria Kharitonova, Luis Torres, Gerardo López-Rodas, Jeffrey J. Liu, Nicolas Singewald, Christoph Schwarzer, Alexandra Lusser
Front Mol Neurosci. 2019; 12: 3. Published online 2019 Jan 23. doi: 10.3389/fnmol.2019.00003
PMCID:
PMC6351481
AbstractArticlePDF–2.2M
9.
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair
T. R. Shenoy, G. Boysen, M. Y. Wang, Q. Z. Xu, W. Guo, F. M. Koh, C. Wang, L. Z. Zhang, Y. Wang, V. Gil, S. Aziz, R. Christova, D. N. Rodrigues, M. Crespo, P. Rescigno, N. Tunariu, R. Riisnaes, Z. Zafeiriou, P. Flohr, W. Yuan, E. Knight, A. Swain, M. Ramalho-Santos, D. Y. Xu, J. de Bono, H. Wu
Ann Oncol. 2017 Jul; 28(7): 1495–1507. Published online 2017 Apr 5. doi: 10.1093/annonc/mdx165
PMCID:
PMC5834074
AbstractArticlePDF–1.4M
10.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
11.
Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription
Fong Ming Koh, Carlos O. Lizama, Priscilla Wong, John S. Hawkins, Ann C. Zovein, Miguel Ramalho-Santos
Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14): E1734–E1743. Published online 2015 Mar 23. doi: 10.1073/pnas.1424850112
PMCID:
PMC4394284
AbstractArticlePDF–1.9M
12.
Embryonic stem cell differentiation requires full length Chd1
Paolo Piatti, Chin Yan Lim, Roxana Nat, Andreas Villunger, Stephan Geley, Yan Ting Shue, Claudia Soratroi, Markus Moser, Alexandra Lusser
Sci Rep. 2015; 5: 8007. Published online 2015 Jan 26. doi: 10.1038/srep08007
PMCID:
PMC4306112
AbstractArticlePDF–2.3M
13.
Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast
Marcela Guzman-Ayala, Michael Sachs, Fong Ming Koh, Courtney Onodera, Aydan Bulut-Karslioglu, Chih-Jen Lin, Priscilla Wong, Rachel Nitta, Jun S. Song, Miguel Ramalho-Santos
Development. 2015 Jan 1; 142(1): 118–127. doi: 10.1242/dev.114843
PMCID:
PMC4299150
AbstractArticle
14.
Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis
Jingwen Wu, Jianqiang Bao, Minkyung Kim, Shuiqiao Yuan, Chong Tang, Huili Zheng, Grant S. Mastick, Chen Xu, Wei Yan
Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28): E2851–E2857. Published online 2014 Jun 30. doi: 10.1073/pnas.1407777111
PMCID:
PMC4104921
AbstractArticlePDF–1.8M
15.
The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1
Peter J Skene, Aaron E Hernandez, Mark Groudine, Steven Henikoff
eLife. 2014; 3: e02042. Published online 2014 Apr 15. doi: 10.7554/eLife.02042
PMCID:
PMC3983905
AbstractArticlePDF–7.2M
16.
Chd1 regulates open chromatin and pluripotency of embryonic stem cells
Alexandre Gaspar-Maia, Adi Alajem, Fanny Polesso, Rupa Sridharan, Michael Mason, Amy Heidersbach, João Ramalho-Santos, Michael T. McManus, Kathrin Plath, Eran Meshorer, Miguel Ramalho-Santos
Nature. Author manuscript; available in PMC 2014 Jan 14.
Published in final edited form as: Nature. 2009 Aug 13; 460(7257): 863–868. Published online 2009 Jul 8. doi: 10.1038/nature08212
PMCID:
PMC3891576
AbstractArticlePDF–3.0M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
Dyna I. Shirasaki, Erin R. Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H. Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A. Loo, X. William Yang
Neuron. Author manuscript; available in PMC 2013 Jul 12.
Published in final edited form as: Neuron. 2012 Jul 12; 75(1): 41–57. doi: 10.1016/j.neuron.2012.05.024
PMCID:
PMC3432264
AbstractArticlePDF–4.9M
19.
Mediator coordinates PIC assembly with recruitment of CHD1
Justin J. Lin, Lynn W. Lehmann, Giancarlo Bonora, Rupa Sridharan, Ajay A. Vashisht, Nancy Tran, Kathrin Plath, James A. Wohlschlegel, Michael Carey
Genes Dev. 2011 Oct 15; 25(20): 2198–2209. doi: 10.1101/gad.17554711
PMCID:
PMC3205589
AbstractArticlePDF–1.5M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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