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Select item 112316651.

Argonaute 2 restored erectile function and corpus cavernosum mitochondrial function by reducing apoptosis in a mouse model of cavernous nerve injury

Yan Huang, Guo Nan Yin, Fang-Yuan Liu, Fitri Rahma Fridayana, Lashkari Niloofar, Minh Nhat Vo, Ji-Kan Ryu

Investig Clin Urol. 2024 Jul; 65(4): 400–410. Published online 2024 Jun 24. doi: 10.4111/icu.20240077

PMCID:: PMC11231665

Abstract Article PDF–24M

Select item 105601142.

hsa_circ_0129047 Upregulates LYVE1 to Inhibit Hepatocellular Carcinoma Progression by Sponging miR-492

Zhenzhen Feng, Jiyuan Wu

Dis Markers. 2023; 2023: 6978234. Published online 2023 Sep 30. doi: 10.1155/2023/6978234

PMCID:: PMC10560114

Abstract Article PDF–1.6M

Select item 105278623.

Oncogenic K-Ras suppresses global miRNA function

Bing Shui, Tyler S. Beyett, Zhengyi Chen, Xiaoyi Li, Gaspare La Rocca, William M. Gazlay, Michael J. Eck, Ken S. Lau, Andrea Ventura, Kevin M. Haigis

Mol Cell. Author manuscript; available in PMC 2024 Jul 20.

Published in final edited form as: Mol Cell. 2023 Jul 20; 83(14): 2509–2523.e13. Published online 2023 Jul 3. doi: 10.1016/j.molcel.2023.06.008

PMCID:: PMC10527862

Abstract Article PDF–1.6M

Select item 102443774.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways

Aditya Kshirsagar, Svetlana Maslov Doroshev, Anna Gorelik, Tsviya Olender, Tamar Sapir, Daisuke Tsuboi, Irit Rosenhek-Goldian, Sergey Malitsky, Maxim Itkin, Amir Argoetti, Yael Mandel-Gutfreund, Sidney R. Cohen, Jacob H. Hanna, Igor Ulitsky, Kozo Kaibuchi, Orly Reiner

Nat Commun. 2023; 14: 3293. Published online 2023 Jun 6. doi: 10.1038/s41467-023-38797-8

PMCID:: PMC10244377

Abstract Article PDF–8.5M

Select item 101610015.

Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase

Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo

Proc Natl Acad Sci U S A. 2023 May 2; 120(18): e2216918120. Published online 2023 Apr 24. doi: 10.1073/pnas.2216918120

PMCID:: PMC10161001

Abstract Article PDF–4.1M

Select item 99180486.

Argonaute 2 Restores Erectile Function by Enhancing Angiogenesis and Reducing Reactive Oxygen Species Production in Streptozotocin (STZ)-Induced Type-1 Diabetic Mice

Fang-Yuan Liu, Guo Nan Yin, Jiyeon Ock, Fitri Rahma Fridayana, Lashkari Niloofar, Yan Huang, Minh Nhat Vo, Jun-Kyu Suh, Soon-Sun Hong, Ju-Hee Kang, Ji-Kan Ryu

Int J Mol Sci. 2023 Feb; 24(3): 2935. Published online 2023 Feb 2. doi: 10.3390/ijms24032935

PMCID:: PMC9918048

Abstract Article PDF–7.7M

Select item 96038607.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 94376108.

STUB1 regulates antiviral RNAi through inducing ubiquitination and degradation of Dicer and AGO2 in mammals

Shumin Zhang, Xuhua Zhang, Yuanyuan Bie, Jing Kong, An Wang, Yang Qiu, Xi Zhou

Virol Sin. 2022 Aug; 37(4): 569–580. Published online 2022 May 6. doi: 10.1016/j.virs.2022.05.001

PMCID:: PMC9437610

Abstract Article PDF–3.0M

Select item 89311079.

Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1^G93A mice

Dillon Shapiro, Ryan Massopust, Thomas Taetzsch, Gregorio Valdez

Sci Rep. 2022; 12: 4630. Published online 2022 Mar 17. doi: 10.1038/s41598-022-08455-y

PMCID:: PMC8931107

Abstract Article PDF–8.0M

Select item 867159010.

Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development

Yin Zhang, Ye-Ya Tan, Pei-Pei Chen, Hui Xu, Shu-Juan Xie, Shi-Jun Xu, Bin Li, Jun-Hao Li, Shun Liu, Jian-Hua Yang, Hui Zhou, Liang-Hu Qu

Cell Death Dis. 2021 Dec; 12(12): 1161. Published online 2021 Dec 14. doi: 10.1038/s41419-021-04436-7

PMCID:: PMC8671590

Abstract Article PDF–5.3M

Select item 844704511.

Retinal Degeneration Caused by Ago2 Disruption

Xue-Jiao Chen, Chang-Jun Zhang, Ya-Han Wang, Zi-Bing Jin

Invest Ophthalmol Vis Sci. 2021 Sep; 62(12): 14. Published online 2021 Sep 16. doi: 10.1167/iovs.62.12.14

PMCID:: PMC8447045

Abstract Article PDF–20M

Select item 815791712.

AGO2 promotes tumor progression in KRAS-driven mouse models of non–small cell lung cancer

Jean Ching-Yi Tien, Seema Chugh, Andrew E. Goodrum, Yunhui Cheng, Rahul Mannan, Yuping Zhang, Lisha Wang, Vijaya L. Dommeti, Xiaoming Wang, Alice Xu, Jennifer Hon, Carson Kenum, Fengyun Su, Rui Wang, Xuhong Cao, Sunita Shankar, Arul M. Chinnaiyan

Proc Natl Acad Sci U S A. 2021 May 18; 118(20): e2026104118. Published online 2021 May 10. doi: 10.1073/pnas.2026104118

PMCID:: PMC8157917

Abstract Article PDF–1.8M

Select item 809881413.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton

Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622

PMCID:: PMC8098814

Abstract Article PDF–7.7M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 790660215.

Repressing Ago2 mRNA translation by Trim71 maintains pluripotency through inhibiting let-7 microRNAs

Qiuying Liu, Xiaoli Chen, Mariah K Novak, Shaojie Zhang, Wenqian Hu

eLife. 2021; 10: e66288. Published online 2021 Feb 18. doi: 10.7554/eLife.66288

PMCID:: PMC7906602

Abstract Article PDF–3.2M

Select item 787517516.

Hepatic Ago2 Regulates PPARα for Oxidative Metabolism Linked to Glycemic Control in Obesity and Post Bariatric Surgery

Jashdeep Bhattacharjee, Vishnupriya J Borra, Esam S B Salem, Cai Zhang, Kazutoshi Murakami, Rupinder K Gill, Ahlee Kim, James K Kim, Rosa-Maria Salazar-Gonzalez, Mikako Warren, Rohit Kohli, Takahisa Nakamura

Endocrinology. 2021 Apr; 162(4): bqab007. Published online 2021 Jan 11. doi: 10.1210/endocr/bqab007

PMCID:: PMC7875175

Abstract Article

Select item 755238117.

Oligodendrocyte-specific Argonaute profiling identifies microRNAs associated with experimental autoimmune encephalomyelitis

Qin Ma, Atsuko Matsunaga, Brenda Ho, Jorge R. Oksenberg, Alessandro Didonna

J Neuroinflammation. 2020; 17: 297. Published online 2020 Oct 12. doi: 10.1186/s12974-020-01964-5

PMCID:: PMC7552381

Abstract Article PDF–2.7M

Select item 746731618.

Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity

Zhengzheng S. Liang, Irene Cimino, Binnaz Yalcin, Narayanan Raghupathy, Valerie E. Vancollie, Ximena Ibarra-Soria, Helen V. Firth, Debra Rimmington, I. Sadaf Farooqi, Christopher J. Lelliott, Steven C. Munger, Stephen O’Rahilly, Anne C. Ferguson-Smith, Anthony P. Coll, Darren W. Logan

PLoS Genet. 2020 Sep; 16(9): e1008916. Published online 2020 Sep 2. doi: 10.1371/journal.pgen.1008916

PMCID:: PMC7467316

Abstract Article PDF–3.4M

Select item 744639719.

High-resolution in vivo identification of miRNA targets by Halo-Enhanced Ago2 Pulldown

Xiaoyi Li, Yuri Pritykin, Carla P. Concepcion, Yuheng Lu, Gaspare La Rocca, Minsi Zhang, Bryan King, Peter J. Cook, Yu Wah Au, Olesja Popow, Joao A. Paulo, Hannah G. Otis, Chiara Mastroleo, Paul Ogrodowski, Ryan Schreiner, Kevin M. Haigis, Doron Betel, Christina S. Leslie, Andrea Ventura

Mol Cell. Author manuscript; available in PMC 2021 Jul 2.

Published in final edited form as: Mol Cell. 2020 Jul 2; 79(1): 167–179.e11. Published online 2020 Jun 3. doi: 10.1016/j.molcel.2020.05.009

PMCID:: PMC7446397

Abstract Article PDF–2.2M

Select item 729503320.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

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