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Items: 1 to 20 of 212

1.
Autophagy impairment and lifespan reduction caused by Atg1 RNAi or Atg18 RNAi expression in adult fruit flies (Drosophila melanogaster)
Mariah Bierlein, Joseph Charles, Trevor Polisuk-Balfour, Heidi Bretscher, Micaela Rice, Jacklyn Zvonar, Drake Pohl, Lindsey Winslow, Brennah Wasie, Sara Deurloo, Jordan Van Wert, Britney Williams, Gabrielle Ankney, Zachary Harmon, Erica Dann, Anna Azuz, Alex Guzman-Vargas, Elizabeth Kuhns, Thomas P Neufeld, Michael B O’Connor, Felix Amissah, Changqi C Zhu
Genetics. 2023 Oct; 225(2): iyad154. Published online 2023 Aug 18. doi: 10.1093/genetics/iyad154
PMCID:
PMC11491525
AbstractArticlePDF–1.6M
2.
Egg multivesicular bodies elicit an LC3-associated phagocytosis-like pathway to degrade paternal mitochondria after fertilization
Sharon Ben-Hur, Shoshana Sernik, Sara Afar, Alina Kolpakova, Yoav Politi, Liron Gal, Anat Florentin, Ofra Golani, Ehud Sivan, Nili Dezorella, David Morgenstern, Shmuel Pietrokovski, Eyal Schejter, Keren Yacobi-Sharon, Eli Arama
Nat Commun. 2024; 15: 5715. Published online 2024 Jul 8. doi: 10.1038/s41467-024-50041-5
PMCID:
PMC11231261
AbstractArticlePDF–8.3M
3.
Endosome mediated nucleocytoplasmic trafficking and endomembrane allocation is crucial to polyglutamine toxicity
Yuyu Nan, Wenfeng Chen, Fei Chen, Lili Wei, Aiyuan Zeng, Xiaohui Lin, Wenbin Zhou, Yufeng Yang, Qinghua Li
Cell Biol Toxicol. 2024; 40(1): 48. Published online 2024 Jun 20. doi: 10.1007/s10565-024-09891-4
PMCID:
PMC11189978
AbstractArticlePDF–14M
4.
O-GlcNAc modification is essential for the regulation of autophagy in Drosophila melanogaster
Sujin Park, Yangsin Lee, Jin Won Pak, Hanbyeol Kim, Hyeonjin Choi, Jae-woo Kim, Jürgen Roth, Jin Won Cho
Cell Mol Life Sci. 2015 Aug; 72(16): 3173–3183. Published online 2015 Apr 4. doi: 10.1007/s00018-015-1889-z
PMCID:
PMC11114044
AbstractArticlePDF–3.6M
5.
Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system
Pingze Zhang, James H. Catterson, Sebastian Grönke, Linda Partridge
Nat Aging. 2024; 4(4): 491–509. Published online 2024 Feb 27. doi: 10.1038/s43587-024-00578-3
PMCID:
PMC11031405
AbstractArticlePDF–12M
6.
Autophagy as a new player in the regulation of clock neurons physiology of Drosophila melanogaster
Kornel Szypulski, Aleksandra Tyszka, Elzbieta Pyza, Milena Damulewicz
Sci Rep. 2024; 14: 6085. Published online 2024 Mar 13. doi: 10.1038/s41598-024-56649-3
PMCID:
PMC10937918
AbstractArticlePDF–2.5M
7.
Interplay between autophagy and CncC regulates dendrite pruning in Drosophila
Jue Yu Kelly Tan, Liang Yuh Chew, Gábor Juhász, Fengwei Yu
Proc Natl Acad Sci U S A. 2024 Mar 5; 121(10): e2310740121. Published online 2024 Feb 26. doi: 10.1073/pnas.2310740121
PMCID:
PMC10927499
AbstractArticlePDF–3.5M
8.
Understanding Developmental Cell Death Using Drosophila as a Model System
Ruchi Umargamwala, Jantina Manning, Loretta Dorstyn, Donna Denton, Sharad Kumar
Cells. 2024 Feb; 13(4): 347. Published online 2024 Feb 16. doi: 10.3390/cells13040347
PMCID:
PMC10886741
AbstractArticlePDF–1.6M
9.
Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
Aitor Martinez, Alvaro Sanchez-Martinez, Jake T. Pickering, Madeleine J. Twyning, Ana Terriente-Felix, Po-Lin Chen, Chun-Hong Chen, Alexander J. Whitworth
Mol Neurodegener. 2024; 19: 12. Published online 2024 Jan 25. doi: 10.1186/s13024-024-00701-3
PMCID:
PMC10811860
AbstractArticlePDF–13M
10.
TDP-43 impairs sleep in Drosophila through Ataxin-2–dependent metabolic disturbance
Alexandra E. Perlegos, Jaclyn Durkin, Samuel J. Belfer, Anyara Rodriguez, Oksana Shcherbakova, Kristen Park, Jenny Luong, Nancy M. Bonini, Matthew S. Kayser
Sci Adv. 2024 Jan 12; 10(2): eadj4457. Published online 2024 Jan 10. doi: 10.1126/sciadv.adj4457
PMCID:
PMC10780954
AbstractArticlePDF–2.1M
11.
Disrupted endoplasmic reticulum-mediated autophagosomal biogenesis in a Drosophila model of C9-ALS-FTD
Hyun Sung, Thomas E. Lloyd
Autophagy. 2024; 20(1): 94–113. Published online 2023 Aug 27. doi: 10.1080/15548627.2023.2249750
PMCID:
PMC10761023
AbstractArticlePDF–7.3M
12.
Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Drosophila
Akanksha Onkar, Deepashree Sheshadri, Anupama Rai, Arjit Kant Gupta, Nitin Gupta, Subramaniam Ganesh
Dis Model Mech. 2023 Oct 1; 16(10): dmm050238. Published online 2023 Oct 19. doi: 10.1242/dmm.050238
PMCID:
PMC10602008
AbstractArticle
13.
Insights into human kidney function from the study of Drosophila
Sybille Koehler, Tobias B. Huber
Pediatr Nephrol. 2023; 38(12): 3875–3887. Published online 2023 May 12. doi: 10.1007/s00467-023-05996-w
PMCID:
PMC10584755
AbstractArticlePDF–1.2M
14.
Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity
Javier Morón-Oset, Lilly Katharina Sophie Fischer, Nathalie Jauré, Pingze Zhang, Annika Julia Jahn, Tessa Supèr, André Pahl, Adrian M. Isaacs, Sebastian Grönke, Linda Partridge
Acta Neuropathol Commun. 2023; 11: 140. Published online 2023 Aug 29. doi: 10.1186/s40478-023-01634-6
PMCID:
PMC10463776
AbstractArticlePDF–10M
15.
Drosophila as a Robust Model System for Assessing Autophagy: A Review
Esref Demir, Sam Kacew
Toxics. 2023 Aug; 11(8): 682. Published online 2023 Aug 8. doi: 10.3390/toxics11080682
PMCID:
PMC10458868
AbstractArticlePDF–1.0M
16.
Toxicity of C9orf72-associated dipeptide repeat peptides is modified by commonly used protein tags
Javier Morón-Oset, Lilly KS Fischer, Mireia Carcolé, Ashling Giblin, Pingze Zhang, Adrian M Isaacs, Sebastian Grönke, Linda Partridge
Life Sci Alliance. 2023 Sep; 6(9): e202201739. Published online 2023 Jun 12. doi: 10.26508/lsa.202201739
PMCID:
PMC10262077
AbstractArticlePDF–2.2M
17.
In Vivo Effects of Crataegus pinnatifida Extract for Healthy Longevity
In-sun Yu, Mina K. Kim, Min Jung Kim, Jaewon Shim
J Microbiol Biotechnol. 2023 May 28; 33(5): 680–686. Published online 2023 Mar 10. doi: 10.4014/jmb.2302.02022
PMCID:
PMC10236174
AbstractArticlePDF–1.6M
18.
LC3-associated phagocytosis promotes glial degradation of axon debris after injury in Drosophila models
Áron Szabó, Virág Vincze, Aishwarya Sanjay Chhatre, András Jipa, Sarolta Bognár, Katalin Eszter Varga, Poulami Banik, Adél Harmatos-Ürmösi, Lukas J. Neukomm, Gábor Juhász
Nat Commun. 2023; 14: 3077. Published online 2023 May 29. doi: 10.1038/s41467-023-38755-4
PMCID:
PMC10227080
AbstractArticlePDF–9.4M
19.
Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila
Shashank Shekhar, Andrew T. Moehlman, Brenden Park, Michael Ewnetu, Charles Tracy, Iris Titos, Krzysztof Pawłowski, Vincent S. Tagliabracci, Helmut Krämer
Nat Commun. 2023; 14: 2932. Published online 2023 May 22. doi: 10.1038/s41467-023-38485-7
PMCID:
PMC10203134
AbstractArticlePDF–4.4M
20.
Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin
Jennifer C. Regan, Yu-Xuan Lu, Enric Ureña, Ralf L. Meilenbrock, James H. Catterson, Disna Kißler, Jenny Fröhlich, Emilie Funk, Linda Partridge
Nat Aging. 2022; 2(12): 1145–1158. Published online 2022 Dec 1. doi: 10.1038/s43587-022-00308-7
PMCID:
PMC10154239
AbstractArticlePDF–7.4M

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