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Select item 96169991.

A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response

Tyler A. U. Hilsabeck, Ru Liu-Bryan, Tracy Guo, Kenneth A. Wilson, Neelanjan Bose, Daniel Raftery, Jennifer N. Beck, Sven Lang, Kelly Jin, Christopher S. Nelson, Tal Oron, Marshall Stoller, Daniel Promislow, Rachel B. Brem, Robert Terkeltaub, Pankaj Kapahi

GeroScience. 2022 Aug; 44(4): 2195–2211. Published online 2022 Apr 6. doi: 10.1007/s11357-022-00557-9

PMCID:: PMC9616999

Abstract Article PDF–3.9M

Select item 92321612.

Single-nucleus RNA-sequencing in pre-cellularization Drosophila melanogaster embryos

Ashley R. Albright, Michael R. Stadler, Michael B. Eisen

PLoS One. 2022; 17(6): e0270471. Published online 2022 Jun 24. doi: 10.1371/journal.pone.0270471

PMCID:: PMC9232161

Abstract Article PDF–1.7M

Select item 91947933.

Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa‐Porthos axis in Drosophila

Shamsi Emtenani, Elliot T Martin, Attila Gyoergy, Julia Bicher, Jakob‐Wendelin Genger, Thomas Köcher, Maria Akhmanova, Mariana Guarda, Marko Roblek, Andreas Bergthaler, Thomas R Hurd, Prashanth Rangan, Daria E Siekhaus

EMBO J. 2022 Jun; 41(12): e109049. Published online 2022 Mar 23. doi: 10.15252/embj.2021109049

PMCID:: PMC9194793

Abstract Article PDF–8.4M

Select item 65065394.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 62944975.

Integrative genomic analysis reveals novel regulatory mechanisms of eyeless during Drosophila eye development

Kelvin Yeung, Feng Wang, Yumei Li, Keqing Wang, Graeme Mardon, Rui Chen

Nucleic Acids Res. 2018 Dec 14; 46(22): 11743–11758. Published online 2018 Oct 8. doi: 10.1093/nar/gky892

PMCID:: PMC6294497

Abstract Article PDF–6.3M

Select item 57078056.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890027.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 53255958.

RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides

Katharine C. Abruzzi, Abigail Zadina, Weifei Luo, Evelyn Wiyanto, Reazur Rahman, Fang Guo, Orie Shafer, Michael Rosbash

PLoS Genet. 2017 Feb; 13(2): e1006613. Published online 2017 Feb 9. doi: 10.1371/journal.pgen.1006613

PMCID:: PMC5325595

Abstract Article PDF–3.1M

Select item 51268649.

Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster

Punita Juneja, Andrew Quinn, Francis M. Jiggins

BMC Genomics. 2016; 17: 981. Published online 2016 Nov 28. doi: 10.1186/s12864-016-3333-7

PMCID:: PMC5126864

Abstract Article PDF–1.1M

Select item 497891910.

Phenotypes Associated with Second Chromosome P Element Insertions in Drosophila melanogaster

Lily Kahsai, Gillian H. Millburn, Kevin R. Cook

G3 (Bethesda) 2016 Aug; 6(8): 2665–2670. Published online 2016 Jun 10. doi: 10.1534/g3.116.030940

PMCID:: PMC4978919

Abstract Article PDF–613K

Select item 462417611.

Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila

Tatiana V. Morozova, Wen Huang, Victoria A. Pray, Thomas Whitham, Robert R. H. Anholt, Trudy F. C. Mackay

BMC Genomics. 2015; 16: 865. Published online 2015 Oct 26. doi: 10.1186/s12864-015-2064-5

PMCID:: PMC4624176

Abstract Article PDF–1.5M

Select item 452833012.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832913.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 439805014.

The Genetic Basis for Variation in Olfactory Behavior in Drosophila melanogaster

Gunjan H. Arya, Michael M. Magwire, Wen Huang, Yazmin L. Serrano-Negron, Trudy F.C. Mackay, Robert R.H. Anholt

Chem Senses. 2015 May; 40(4): 233–243. Published online 2015 Feb 15. doi: 10.1093/chemse/bjv001

PMCID:: PMC4398050

Abstract Article PDF–8.9M

Select item 435288715.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114