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Select item 111494911.

Decreased Tiam1‐mediated Rac1 activation is responsible for impaired directional persistence of chondrocyte migration in microtia

Yi Wu, Wei Liu, Jia Li, Hang Shi, Shize Ma, Di Wang, Bo Pan, Ran Xiao, Haiyue Jiang, Xia Liu

J Cell Mol Med. 2024 Jun; 28(11): e18443. Published online 2024 Jun 4. doi: 10.1111/jcmm.18443

PMCID:: PMC11149491

Abstract Article PDF–29M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107345503.

Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Nikhil Sharma, Patricia Kessler, Ganes C. Sen

J Virol. 2023 Dec; 97(12): e01304-23. Published online 2023 Nov 20. doi: 10.1128/jvi.01304-23

PMCID:: PMC10734550

Abstract Article PDF–913K

Select item 92185154.

PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c

Asli E. Dogan, Syed M. Hamid, Asli D. Yildirim, Zehra Yildirim, Ganes Sen, Celine E. Riera, Roberta A. Gottlieb, Ebru Erbay

J Biol Chem. 2022 Jul; 298(7): 102050. Published online 2022 May 19. doi: 10.1016/j.jbc.2022.102050

PMCID:: PMC9218515

Abstract Article PDF–1.2M

Select item 79486455.

Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells

Chandan Gurung, Mona Fendereski, Krishna Sapkota, Jason Guo, Faqing Huang, Yan-Lin Guo

J Biol Chem. 2021 Jan-Jun; 296: 100264. Published online 2021 Jan 8. doi: 10.1016/j.jbc.2021.100264

PMCID:: PMC7948645

Abstract Article PDF–1.7M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 79199477.

Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling

Lauren S. Vaughn, Evelyn Chukwurah, Rekha C Patel

Biochem J. Author manuscript; available in PMC 2022 Feb 12.

Published in final edited form as: Biochem J. 2021 Feb 12; 478(3): 493–510. doi: 10.1042/BCJ20200987

PMCID:: PMC7919947

Abstract Article PDF–1.6M

Select item 78487498.

A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells

Kazuhiro Murakami, Yumi Terakado, Kikue Saito, Yoshie Jomen, Haruna Takeda, Masanobu Oshima, Nick Barker

Proc Natl Acad Sci U S A. 2021 Jan 26; 118(4): e2016806118. Published online 2021 Jan 21. doi: 10.1073/pnas.2016806118

PMCID:: PMC7848749

Abstract Article PDF–3.2M

Select item 66927709.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 660230010.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 596840311.

PKR modulates abnormal brain signaling in experimental obesity

Mariko Taga, François Mouton-Liger, Malha Sadoune, Sarah Gourmaud, Jenny Norman, Marion Tible, Sylvie Thomasseau, Claire Paquet, James A. R. Nicoll, Delphine Boche, Jacques Hugon

PLoS One. 2018; 13(5): e0196983. Published online 2018 May 24. doi: 10.1371/journal.pone.0196983

PMCID:: PMC5968403

Abstract Article PDF–15M

Select item 588714512.

Functional Redundancy of DICER Cofactors TARBP2 and PRKRA During Murine Embryogenesis Does Not Involve miRNA Biogenesis

Sri Ramulu N. Pullagura, Bill Buaas, Nichelle Gray, Lindsey C. Krening, Anuj Srivastava, Robert E. Braun

Genetics. 2018 Apr; 208(4): 1513–1522. Published online 2018 Feb 21. doi: 10.1534/genetics.118.300791

PMCID:: PMC5887145

Abstract Article PDF–1.3M

Select item 473361613.

Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology

Kristina Palmer, Heather Fairfield, Suhaib Borgeia, Michelle Curtain, Mohamed G. Hassan, Louise Dionne, Son Yong Karst, Harold Coombs, Laura G. Reinholdt, David E. Bergstrom, Leah Rae Donahue, Timothy C. Cox, Stephen A. Murray

Dev Biol. Author manuscript; available in PMC 2017 Jul 15.

Published in final edited form as: Dev Biol. 2016 Jul 15; 415(2): 216–227. Published online 2015 Jul 31. doi: 10.1016/j.ydbio.2015.07.023

PMCID:: PMC4733616

Abstract Article PDF–827K

Select item 471552014.

The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

Benjamin K. Dickerman, Christine L. White, Patricia M. Kessler, Anthony J. Sadler, Bryan R.G. Williams, Ganes C. Sen

FEBS J. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: FEBS J. 2015 Dec; 282(24): 4766–4781. Published online 2015 Oct 26. doi: 10.1111/febs.13533

PMCID:: PMC4715520

Abstract Article PDF–2.1M

Select item 465392515.

PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load

David Chun-Hei Poon, Yuen-Shan Ho, Ran You, Hei-Long Tse, Kin Chiu, Raymond Chuen-Chung Chang

J Neuroinflammation. 2015; 12: 212. Published online 2015 Nov 19. doi: 10.1186/s12974-015-0433-2

PMCID:: PMC4653925

Abstract Article PDF–1.5M

Select item 448439216.

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, Rangjiao Liu, Martin Kircher, Anuradha Lakshminarayana, Belinda S. Harris, Son Yong Karst, Louise A. Dionne, Coleen C. Kane, Michelle Curtain, Melissa L. Berry, Patricia F. Ward-Bailey, Ian Greenstein, Candice Byers, Anne Czechanski, Jocelyn Sharp, Kristina Palmer, Polyxeni Gudis, Whitney Martin, Abby Tadenev, Laurent Bogdanik, C. Herbert Pratt, Bo Chang, David G. Schroeder, Gregory A. Cox, Paul Cliften, Jeffrey Milbrandt, Stephen Murray, Robert Burgess, David E. Bergstrom, Leah Rae Donahue, Hanan Hamamy, Amira Masri, Federico A. Santoni, Periklis Makrythanasis, Stylianos E. Antonarakis, Jay Shendure, Laura G. Reinholdt

Genome Res. 2015 Jul; 25(7): 948–957. doi: 10.1101/gr.186882.114