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Select item 109017391.

A single-cell time-lapse of mouse prenatal development from gastrula to birth

Chengxiang Qiu, Beth K. Martin, Ian C. Welsh, Riza M. Daza, Truc-Mai Le, Xingfan Huang, Eva K. Nichols, Megan L. Taylor, Olivia Fulton, Diana R. O’Day, Anne Roshella Gomes, Saskia Ilcisin, Sanjay Srivatsan, Xinxian Deng, Christine M. Disteche, William Stafford Noble, Nobuhiko Hamazaki, Cecilia B. Moens, David Kimelman, Junyue Cao, Alexander F. Schier, Malte Spielmann, Stephen A. Murray, Cole Trapnell, Jay Shendure

Nature. 2024; 626(8001): 1084–1093. Published online 2024 Feb 14. doi: 10.1038/s41586-024-07069-w

PMCID:: PMC10901739

Abstract Article PDF–63M

Select item 103904922.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 101104233.

Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development

Alyssa M. McCoy, Omar Lakhdari, Sayane Shome, Kaitlin Caoili, Gilberto E. Hernandez, Nima Aghaeepour, Lindsay D. Butcher, Kathleen Fisch, Lawrence S. Prince

Development. 2023 Mar 1; 150(5): dev200839. Published online 2023 Mar 3. doi: 10.1242/dev.200839

PMCID:: PMC10110423

Abstract Article

Select item 100730084.

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways

Xuming Zhu, Mingang Xu, N. Adrian Leu, Edward E. Morrisey, Sarah E. Millar

Dis Model Mech. 2023 Mar 1; 16(3): dmm049876. Published online 2023 Mar 24. doi: 10.1242/dmm.049876

PMCID:: PMC10073008

Abstract Article

Select item 99428805.

Cardiac progenitors instruct second heart field fate through Wnts

Matthew Miyamoto, Suraj Kannan, Matthew J. Anderson, Xihe Liu, David Suh, Myo Htet, Biyi Li, Tejasvi Kakani, Sean Murphy, Emmanouil Tampakakis, Mark Lewandoski, Peter Andersen, Hideki Uosaki, Chulan Kwon

Proc Natl Acad Sci U S A. 2023 Jan 24; 120(4): e2217687120. Published online 2023 Jan 17. doi: 10.1073/pnas.2217687120

PMCID:: PMC9942880

Abstract Article PDF–2.0M

Select item 98457456.

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development

Laura Simonson, Ethan Oldham, Hao Chang

Development. 2022 Nov 15; 149(22): dev200816. Published online 2022 Nov 16. doi: 10.1242/dev.200816

PMCID:: PMC9845745

Abstract Article

Select item 96817487.

Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling

Douglas G. Brownfield, Alex Diaz de Arce, Elisa Ghelfi, Astrid Gillich, Tushar J. Desai, Mark A. Krasnow

Nat Commun. 2022; 13: 7137. Published online 2022 Nov 21. doi: 10.1038/s41467-022-34059-1

PMCID:: PMC9681748

Abstract Article PDF–3.6M

Select item 96429988.

A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene

Yonghe Ding, Di Lang, Jianhua Yan, Haisong Bu, Hongsong Li, Kunli Jiao, Jingchun Yang, Haibo Ni, Stefano Morotti, Tai Le, Karl J Clark, Jenna Port, Stephen C Ekker, Hung Cao, Yuji Zhang, Jun Wang, Eleonora Grandi, Zhiqiang Li, Yongyong Shi, Yigang Li, Alexey V Glukhov, Xiaolei Xu

eLife. 2022; 11: e77327. Published online 2022 Oct 18. doi: 10.7554/eLife.77327

PMCID:: PMC9642998

Abstract Article PDF–2.1M

Select item 95315359.

NOTCH maintains developmental cardiac gene network through WNT5A

Yidong Wang, Pengfei Lu, Bingruo Wu, Bernice E. Morrow, Bin Zhou

J Mol Cell Cardiol. Author manuscript; available in PMC 2022 Oct 4.

Published in final edited form as: J Mol Cell Cardiol. 2018 Dec; 125: 98–105. Published online 2018 Oct 19. doi: 10.1016/j.yjmcc.2018.10.014

PMCID:: PMC9531535

Abstract Article PDF–1.3M

Select item 948196910.

Integrated analysis of Wnt signalling system component gene expression

Paula Murphy, Chris Armit, Bill Hill, Shanmugasundaram Venkataraman, Patrick Frankel, Richard A. Baldock, Duncan R. Davidson

Development. 2022 Aug 15; 149(16): dev200312. Published online 2022 Aug 15. doi: 10.1242/dev.200312

PMCID:: PMC9481969

Abstract Article

Select item 918154111.

Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway

Guangying Yang, Shan Lu, Jia Jiang, Jun Weng, Xiaomei Zeng

Int J Mol Sci. 2022 Jun; 23(11): 6014. Published online 2022 May 27. doi: 10.3390/ijms23116014

PMCID:: PMC9181541

Abstract Article PDF–4.4M

Select item 916859912.

Activation of PI3K/p110α in the Lung Mesenchyme Affects Branching Morphogenesis and Club Cell Differentiation

Haiting Dai, Mingli Zhu, Wenya Li, Guohui Si, Yiming Xing

Front Cell Dev Biol. 2022; 10: 880206. Published online 2022 May 23. doi: 10.3389/fcell.2022.880206

PMCID:: PMC9168599

Abstract Article PDF–4.4M

Select item 872239013.

A single-cell atlas of mouse lung development

Nicholas M. Negretti, Erin J. Plosa, John T. Benjamin, Bryce A. Schuler, A. Christian Habermann, Christopher S. Jetter, Peter Gulleman, Claire Bunn, Alice N. Hackett, Meaghan Ransom, Chase J. Taylor, David Nichols, Brittany K. Matlock, Susan H. Guttentag, Timothy S. Blackwell, Nicholas E. Banovich, Jonathan A. Kropski, Jennifer M. S. Sucre

Development. 2021 Dec 15; 148(24): dev199512. Published online 2021 Dec 20. doi: 10.1242/dev.199512

PMCID:: PMC8722390

Abstract Article

Select item 858141614.

hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9

Yujiao Wen, Xixiang Ma, Xiaoli Wang, Fengli Wang, Juan Dong, Yanqing Wu, Chunyu Lv, Kuan Liu, Yan Zhang, Zhibing Zhang, Shuiqiao Yuan

Theranostics. 2021; 11(20): 10030–10046. Published online 2021 Oct 25. doi: 10.7150/thno.66819

PMCID:: PMC8581416

Abstract Article PDF–3.5M

Select item 832001715.

The genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus

Jarod A. Zepp, Michael P. Morley, Claudia Loebel, Madison M. Kremp, Fatima N. Chaudhry, Maria C. Basil, John P. Leach, Derek C. Liberti, Terren K. Niethamer, Yun Ying, Sowmya Jayachandran, Apoorva Babu, Su Zhou, David B. Frank, Jason A. Burdick, Edward E. Morrisey

Science. Author manuscript; available in PMC 2021 Sep 12.

Published in final edited form as: Science. 2021 Mar 12; 371(6534): eabc3172. doi: 10.1126/science.abc3172

PMCID:: PMC8320017

Abstract Article PDF–5.9M

Select item 816920716.

Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation

Chaohui Zhang, Yuxin Li, Jiaheng Cao, Beibei Yu, Kaiyue Zhang, Ke Li, Xinhui Xu, Zhikun Guo, Yinming Liang, Xiao Yang, Zhongzhou Yang, Yunfu Sun, Vesa Kaartinen, Keyue Ding, Jikui Wang

Open Biol. 2021 Jun; 11(6): 210020. Published online June 2, 2021. doi: 10.1098/rsob.210020

PMCID:: PMC8169207

Abstract Article PDF–2.4M

Select item 793877017.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003