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Select item 104936651.

Degradation of NLRP3 by p62‐dependent‐autophagy improves cognitive function in Alzheimer's disease by maintaining the phagocytic function of microglia

Dongyuan Zhang, Yu Zhang, Jirong Pan, Jingjing Cao, Xiuping Sun, Xianglei Li, Ling Zhang, Chuan Qin

CNS Neurosci Ther. 2023 Oct; 29(10): 2826–2842. Published online 2023 Apr 18. doi: 10.1111/cns.14219

PMCID:: PMC10493665

Abstract Article PDF–29M

Select item 104800592.

Targeting Clic1 for the treatment of obesity: A novel therapeutic strategy to reduce food intake and body weight

Rizaldy C. Zapata, Dinghong Zhang, Dongmin Yoon, Chanond A. Nasamran, Daisy R. Chilin-Fuentes, Avraham Libster, Besma S. Chaudry, Mariela Lopez-Valencia, Devasena Ponnalagu, Harpreet Singh, Michael Petrascheck, Olivia Osborn

Mol Metab. 2023 Oct; 76: 101794. Published online 2023 Aug 20. doi: 10.1016/j.molmet.2023.101794

PMCID:: PMC10480059

Abstract Article PDF–1.7M

Select item 94819333.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 87224294.

CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and function

De Yu Mao, Matthew L. Kleinjan, Irina Jilishitz, Bhairavi Swaminathan, Hideru Obinata, Yulia A. Komarova, Kayla J. Bayless, Timothy Hla, Jan K. Kitajewski

Sci Signal. Author manuscript; available in PMC 2022 Jan 3.

Published in final edited form as: Sci Signal. 2021 Apr 20; 14(679): eabc0425. Published online 2021 Apr 20. doi: 10.1126/scisignal.abc0425

PMCID:: PMC8722429

Abstract Article PDF–1.7M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 72019267.

Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth

Michelle A. Francisco, Siyi Wanggou, Jerry J. Fan, Weifan Dong, Xin Chen, Ali Momin, Namal Abeysundara, Hyun-Kee Min, Jade Chan, Rochelle McAdam, Marian Sia, Ronwell J. Pusong, Shixuan Liu, Nish Patel, Vijay Ramaswamy, Noriyuki Kijima, Lu-Yang Wang, Yuanquan Song, Ran Kafri, Michael D. Taylor, Xuejun Li, Xi Huang

J Exp Med. 2020 May 4; 217(5): e20190971. Published online 2020 Feb 25. doi: 10.1084/jem.20190971

PMCID:: PMC7201926

Abstract Article PDF–8.5M

Select item 69939258.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 63334609.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 624418310.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 554470611.

CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation

Tiantian Tang, Xueting Lang, Congfei Xu, Xiaqiong Wang, Tao Gong, Yanqing Yang, Jun Cui, Li Bai, Jun Wang, Wei Jiang, Rongbin Zhou

Nat Commun. 2017; 8: 202. Published online 2017 Aug 4. doi: 10.1038/s41467-017-00227-x

PMCID:: PMC5544706

Abstract Article PDF–1.7M

Select item 551935912.

The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome

Raquel Domingo-Fernández, Rebecca C. Coll, Jay Kearney, Samuel Breit, Luke A. J. O'Neill

J Biol Chem. 2017 Jul 21; 292(29): 12077–12087. Published online 2017 Jun 2. doi: 10.1074/jbc.M117.797126

PMCID:: PMC5519359

Abstract Article PDF–2.0M

Select item 538122613.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 535017714.

CLIC1 null mice demonstrate a role for CLIC1 in macrophage superoxide production and tissue injury

Barbara Ulmasov, Jonathan Bruno, Kiyoko Oshima, Yao‐Wen Cheng, Stephen P. Holly, Leslie V. Parise, Terrance M. Egan, John C. Edwards

Physiol Rep. 2017 Mar; 5(5): e13169. Published online 2017 Mar 8. doi: 10.14814/phy2.13169

PMCID:: PMC5350177

Abstract Article PDF–7.0M

Select item 534152015.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

Select item 511579316.

CLIC1 Inhibition Attenuates Vascular Inflammation, Oxidative Stress, and Endothelial Injury

Yingling Xu, Ji Zhu, Xiao Hu, Cui Wang, Dezhao Lu, Chenxue Gong, Jinhuan Yang, Lei Zong

PLoS One. 2016; 11(11): e0166790. Published online 2016 Nov 18. doi: 10.1371/journal.pone.0166790

PMCID:: PMC5115793

Abstract Article PDF–2.5M

Select item 497241817.

Gene expression analysis of the embryonic subplate

Franziska M. Oeschger, Wei-Zhi Wang, Sheena Lee, Fernando García-Moreno, André M. Goffinet, Mariona Arbones, Sonia Rakic, Zoltán Molnár

Cereb Cortex. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Cereb Cortex. 2012 Jun; 22(6): 1343–1359. Published online 2011 Aug 22. doi: 10.1093/cercor/bhr197

PMCID:: PMC4972418

Abstract Article PDF–7.1M

Select item 487436018.

CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis

Kanin Salao, Lele Jiang, Hui Li, Vicky W.-W. Tsai, Yasmin Husaini, Paul M. G. Curmi, Louise J. Brown, David A. Brown, Samuel N. Breit

Biol Open. 2016 May 15; 5(5): 620–630. Published online 2016 Apr 25. doi: 10.1242/bio.018119

PMCID:: PMC4874360

Abstract Article PDF–1.6M

Select item 459183819.

The E3 Ubiquitin Ligases, HUWE1 and NEDD4-1, Are Involved in the Post-translational Regulation of the ABCG1 and ABCG4 Lipid Transporters

Shereen M. Aleidi, Vicky Howe, Laura J. Sharpe, Alryel Yang, Geetha Rao, Andrew J. Brown, Ingrid C. Gelissen

J Biol Chem. 2015 Oct 2; 290(40): 24604–24613. Published online 2015 Aug 20. doi: 10.1074/jbc.M115.675579

PMCID:: PMC4591838

Abstract Article PDF–1.2M

Select item 451121320.

Histone H3.3 maintains genome integrity during mammalian development

Chuan-Wei Jang, Yoichiro Shibata, Joshua Starmer, Della Yee, Terry Magnuson

Genes Dev. 2015 Jul 1; 29(13): 1377–1392. doi: 10.1101/gad.264150.115

PMCID:: PMC4511213

Abstract Article PDF–881K

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