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Items: 1 to 20 of 33

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice
Jennifer E. Kay, Joshua J. Corrigan, Amanda L. Armijo, Ilana S. Nazari, Ishwar N. Kohale, Dorothea K. Torous, Svetlana L. Avlasevich, Robert G. Croy, Dushan N. Wadduwage, Sebastian E. Carrasco, Stephen D. Dertinger, Forest M. White, John M. Essigmann, Leona D. Samson, Bevin P. Engelward
Cell Rep. Author manuscript; available in PMC 2021 Oct 20.
Published in final edited form as: Cell Rep. 2021 Mar 16; 34(11): 108864. doi: 10.1016/j.celrep.2021.108864
PMCID:
PMC8527524
AbstractArticlePDF–1.3M
3.
Inflammation, necrosis, and the kinase RIP3 are key mediators of AAG-dependent alkylation-induced retinal degeneration
Mariacarmela Allocca, Joshua J. Corrigan, Aprotim Mazumder, Kimberly R. Fake, Leona D. Samson
Sci Signal. Author manuscript; available in PMC 2020 Apr 11.
Published in final edited form as: Sci Signal. 2019 Feb 12; 12(568): eaau9216. Published online 2019 Feb 12. doi: 10.1126/scisignal.aau9216
PMCID:
PMC7150588
AbstractArticlePDF–3.2M
4.
Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition
Fahad A. Alhumaydhi, Debora de O. Lopes, Diana L. Bordin, Abdullah S. M. Aljohani, Cameron B. Lloyd, Michael D. McNicholas, Larissa Milano, Clara F. Charlier, Izabel Villela, João Antonio P. Henriques, Kathryn E. Plant, Ruan M. Elliott, Lisiane B. Meira
Sci Rep. 2020; 10: 2209. Published online 2020 Feb 10. doi: 10.1038/s41598-020-59072-6
PMCID:
PMC7010680
AbstractArticlePDF–1.7M
5.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
6.
ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage
Jennifer J Jordan, Sophea Chhim, Carrie M Margulies, Mariacarmela Allocca, Roderick T Bronson, Arne Klungland, Leona D Samson, Dragony Fu
Cell Death Dis. 2017 Jul; 8(7): e2947. Published online 2017 Jul 20. doi: 10.1038/cddis.2017.343
PMCID:
PMC5550884
AbstractArticlePDF–2.1M
7.
Roles of Aag,Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions
Changjun You, Pengcheng Wang, Stephanie L. Nay, Jianshuang Wang, Xiaoxia Dai, Timothy R. O’Connor, Yinsheng Wang
ACS Chem Biol. Author manuscript; available in PMC 2017 May 20.
Published in final edited form as: ACS Chem Biol. 2016 May 20; 11(5): 1332–1338. Published online 2016 Mar 4. doi: 10.1021/acschembio.6b00085
PMCID:
PMC5038138
AbstractArticlePDF–1.1M
8.
AlkB homolog 2 (ABH2) mediated repair of ethenoadenine lesions in mammalian DNA
Jeanette Ringvoll, Marivi N. Moen, Line M. Nordstrand, Lisiane B. Meira, Bo Pang, Anders Bekkelund, Peter C. Dedon, Svein Bjelland, Leona D. Samson, Pål Ø. Falnes, Arne Klungland
Cancer Res. Author manuscript; available in PMC 2016 Jan 25.
Published in final edited form as: Cancer Res. 2008 Jun 1; 68(11): 4142–4149. doi: 10.1158/0008-5472.CAN-08-0796
PMCID:
PMC4725713
AbstractArticlePDF–1.6M
9.
Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney
Mohammad R. Ebrahimkhani, Ali Daneshmand, Aprotim Mazumder, Mariacarmela Allocca, Jennifer A. Calvo, Nona Abolhassani, Iny Jhun, Sureshkumar Muthupalani, Cenk Ayata, Leona D. Samson
Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45): E4878–E4886. Published online 2014 Oct 27. doi: 10.1073/pnas.1413582111
PMCID:
PMC4234618
AbstractArticlePDF–1.6M
10.
DNA glycosylase activity and cell proliferation are key factors in modulating homologous recombination in vivo
Orsolya Kiraly, Guanyu Gong, Megan D. Roytman, Yoshiyuki Yamada, Leona D. Samson, Bevin P. Engelward
Carcinogenesis. 2014 Nov; 35(11): 2495–2502. Published online 2014 Aug 25. doi: 10.1093/carcin/bgu177
PMCID:
PMC4216056
AbstractArticlePDF–3.3M
11.
DNA breaks and chromosomal aberrations arise when replication meets base excision repair
Michael Ensminger, Lucie Iloff, Christian Ebel, Teodora Nikolova, Bernd Kaina, Markus Lӧbrich
J Cell Biol. 2014 Jul 7; 206(1): 29–43. doi: 10.1083/jcb.201312078
PMCID:
PMC4085701
AbstractArticlePDF–3.3M
12.
The Effect of Msh2 Knockdown on Toxicity Induced by tert-Butyl-hydroperoxide, Potassium Bromate, and Hydrogen Peroxide in Base Excision Repair Proficient and Deficient Cells
N. Cooley, R. H. Elder, A. C. Povey
Biomed Res Int. 2013; 2013: 152909. Published online 2013 Aug 4. doi: 10.1155/2013/152909
PMCID:
PMC3747367
AbstractArticlePDF–1.4M
13.
Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1
Jennifer A. Calvo, Catherine A. Moroski-Erkul, Annabelle Lake, Lindsey W. Eichinger, Dharini Shah, Iny Jhun, Prajit Limsirichai, Roderick T. Bronson, David C. Christiani, Lisiane B. Meira, Leona D. Samson
PLoS Genet. 2013 Apr; 9(4): e1003413. Published online 2013 Apr 4. doi: 10.1371/journal.pgen.1003413
PMCID:
PMC3617098
AbstractArticlePDF–16M
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
DNA repair is indispensable for survival after acute inflammation
Jennifer A. Calvo, Lisiane B. Meira, Chun-Yue I. Lee, Catherine A. Moroski-Erkul, Nona Abolhassani, Koli Taghizadeh, Lindsey W. Eichinger, Sureshkumar Muthupalani, Line M. Nordstrand, Arne Klungland, Leona D. Samson
J Clin Invest. 2012 Jul 2; 122(7): 2680–2689. Published online 2012 Jun 11. doi: 10.1172/JCI63338
PMCID:
PMC3386829
AbstractArticlePDF–2.0M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis
Stefan Wirtz, Georg Nagel, Leonid Eshkind, Markus F. Neurath, Leona D. Samson, Bernd Kaina
Carcinogenesis. 2010 Dec; 31(12): 2111–2117. Published online 2010 Aug 23. doi: 10.1093/carcin/bgq174
PMCID:
PMC2994278
AbstractArticlePDF–864K
18.
Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase
Larry E. Jones, Jr, Lei Ying, Anne B. Hofseth, Elena Jelezcova, Robert W. Sobol, Stefan Ambs, Curtis C. Harris, Michael Graham Espey, Lorne J. Hofseth, Michael D. Wyatt
Carcinogenesis. 2009 Dec; 30(12): 2123–2129. Published online 2009 Oct 28. doi: 10.1093/carcin/bgp256
PMCID:
PMC2792317
AbstractArticlePDF–526K
19.
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
Irina V. Kovtun, Yuan Liu, Magnar Bjoras, Arne Klungland, Samuel H. Wilson, Cynthia T. McMurray
Nature. Author manuscript; available in PMC 2009 May 13.
Published in final edited form as: Nature. 2007 May 24; 447(7143): 447–452. Published online 2007 Apr 22. doi: 10.1038/nature05778
PMCID:
PMC2681094
AbstractArticlePDF–1.5M
20.
Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice
Lisiane B. Meira, Catherine A. Moroski-Erkul, Stephanie L. Green, Jennifer A. Calvo, Roderick T. Bronson, Dharini Shah, Leona D. Samson
Proc Natl Acad Sci U S A. 2009 Jan 20; 106(3): 888–893. Published online 2009 Jan 12. doi: 10.1073/pnas.0807030106
PMCID:
PMC2621254
AbstractArticlePDF–1.0M

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