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Select item 99590611.

A New In Vivo Zebrafish Bioassay Evaluating Liver Steatosis Identifies DDE as a Steatogenic Endocrine Disruptor, Partly through SCD1 Regulation

Hélène Le Mentec, Emmanuelle Monniez, Antoine Legrand, Céline Monvoisin, Dominique Lagadic-Gossmann, Normand Podechard

Int J Mol Sci. 2023 Feb; 24(4): 3942. Published online 2023 Feb 15. doi: 10.3390/ijms24043942

PMCID:: PMC9959061

Abstract Article PDF–10M

Select item 97451992.

Proper modulation of AHR signaling is necessary for establishing neural connectivity and oligodendrocyte precursor cell development in the embryonic zebrafish brain

Nathan R. Martin, Ratna Patel, Michelle E. Kossack, Lucy Tian, Manuel A. Camarillo, Layra G. Cintrón-Rivera, Joseph C. Gawdzik, Monica S. Yue, Favour O. Nwagugo, Loes M. H. Elemans, Jessica S. Plavicki

Front Mol Neurosci. 2022; 15: 1032302. Published online 2022 Nov 29. doi: 10.3389/fnmol.2022.1032302

PMCID:: PMC9745199

Abstract Article PDF–2.6M

Select item 93083963.

The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior

Prarthana Shankar, Gloria R Garcia, Jane K La Du, Christopher M Sullivan, Cheryl L Dunham, Britton C Goodale, Katrina M Waters, Stanislau Stanisheuski, Claudia S Maier, Preethi Thunga, David M Reif, Robyn L Tanguay

Toxicol Sci. 2022 Jun; 187(2): 325–344. Published online 2022 Apr 4. doi: 10.1093/toxsci/kfac037

PMCID:: PMC9308396

Abstract Article PDF–1.6M

Select item 85344844.

KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer’s Disease

Tohid Siddiqui, Prabesh Bhattarai, Stanislava Popova, Mehmet Ilyas Cosacak, Sanjeev Sariya, Yixin Zhang, Richard Mayeux, Giuseppe Tosto, Caghan Kizil

Cells. 2021 Oct; 10(10): 2748. Published online 2021 Oct 14. doi: 10.3390/cells10102748

PMCID:: PMC8534484

Abstract Article PDF–3.6M

Select item 81131215.

The ecotoxicological contaminant Tris(4-chlorophenyl)methanol (TCPMOH) impacts embryonic development in zebrafish (Danio rerio)

Julian Navarrete, Peyton Wilson, Nicholas Allsing, Chandi Gordon, Rachel Margolis, Ashley V. Schwartz, Christine Cho, Brynn Rogowski, Jennifer Topps, Uduak Z. George, Karilyn E. Sant

Aquat Toxicol. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Aquat Toxicol. 2021 Jun; 235: 105815. Published online 2021 Mar 26. doi: 10.1016/j.aquatox.2021.105815

PMCID:: PMC8113121

Abstract Article PDF–1.1M

Select item 75300526.

The sulfate metabolite of 3,3’-dichlorobiphenyl (PCB-11) impairs Cyp1a activity and increases hepatic neutral lipids in zebrafish larvae (Danio rerio)

Monika A. Roy, Perseverance R. Duche, Alicia R. Timme-Laragy

Chemosphere. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Chemosphere. 2020 Dec; 260: 127609. Published online 2020 Jul 11. doi: 10.1016/j.chemosphere.2020.127609

PMCID:: PMC7530052

Abstract Article PDF–2.0M

Select item 73571787.

Aryl Hydrocarbon Receptor Mediates Larval Zebrafish Fin Duplication Following Exposure to Benzofluoranthenes

Michael A Garland, Mitra C Geier, Sean M Bugel, Prarthana Shankar, Cheryl L Dunham, Joseph M Brown, Susan C Tilton, Robyn L Tanguay

Toxicol Sci. 2020 Jul; 176(1): 46–64. Published online 2020 May 8. doi: 10.1093/toxsci/kfaa063

PMCID:: PMC7357178

Abstract Article PDF–2.2M

Select item 70274358.

The emerging contaminant 3,3’-dichlorobiphenyl (PCB-11) impedes Ahr activation and Cyp1a activity to modify embryotoxicity of Ahr ligands in the zebrafish embryo model (Danio rerio)

Monika A. Roy, Karilyn E. Sant, Olivia L. Venezia, Alix B. Shipman, Stephen D. McCormick, Panithi Saktrakulkla, Keri C. Hornbuckle, Alicia R. Timme-Laragy

Environ Pollut. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Environ Pollut. 2019 Nov; 254(Pt A): 113027. Published online 2019 Aug 6. doi: 10.1016/j.envpol.2019.113027

PMCID:: PMC7027435

Abstract Article PDF–1.3M

Select item 67898189.

Toxicity of Aqueous L-Selenomethionine and Tert-Butyl Hydroperoxide Exposure to Zebrafish (Danio rerio) Embryos Following Tert-Butyl Hydroquinone Treatment

Allyson K. Gerhart, David M. Janz

Toxics. 2019 Sep; 7(3): 44. Published online 2019 Aug 29. doi: 10.3390/toxics7030044

PMCID:: PMC6789818

Abstract Article PDF–2.5M

Select item 659218610.

ahr2, But Not ahr1a or ahr1b, Is Required for Craniofacial and Fin Development and TCDD-dependent Cardiotoxicity in Zebrafish

Jaclyn P Souder, Daniel A Gorelick

Toxicol Sci. 2019 Jul; 170(1): 25–44. Published online 2019 Mar 25. doi: 10.1093/toxsci/kfz075

PMCID:: PMC6592186

Abstract Article PDF–1.7M

Select item 656638711.

Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard

Prarthana Shankar, Mitra C. Geier, Lisa Truong, Ryan S. McClure, Paritosh Pande, Katrina M. Waters, Robert L. Tanguay

Int J Mol Sci. 2019 May; 20(10): 2570. Published online 2019 May 25. doi: 10.3390/ijms20102570

PMCID:: PMC6566387

Abstract Article PDF–6.3M

Select item 608748412.

Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish

Mitra C. Geier, D. James Minick, Lisa Truong, Susan Tilton, Paritosh Pande, Kim A. Anderson, Justin Teeguardan, Robert L. Tanguay

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2018 Sep 1; 354: 115–125. Published online 2018 Apr 6. doi: 10.1016/j.taap.2018.03.029

PMCID:: PMC6087484

Abstract Article PDF–908K

Select item 583224013.

AHR2 required for normal behavioral responses and proper development of the skeletal and reproductive systems in zebrafish

Gloria R. Garcia, Sean M. Bugel, Lisa Truong, Sean Spagnoli, Robert L. Tanguay

PLoS One. 2018; 13(3): e0193484. Published online 2018 Mar 1. doi: 10.1371/journal.pone.0193484

PMCID:: PMC5832240

Abstract Article PDF–12M

Select item 556073614.

Genetic dissection of endothelial transcriptional activity of zebrafish aryl hydrocarbon receptors (AHRs)

Wade W. Sugden, Roberto C. Leonardo-Mendonça, Darío Acuña-Castroviejo, Arndt F. Siekmann

PLoS One. 2017; 12(8): e0183433. Published online 2017 Aug 17. doi: 10.1371/journal.pone.0183433

PMCID:: PMC5560736

Abstract Article PDF–48M

Select item 553996615.

Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish

Andrea L. Knecht, Lisa Truong, Skylar W. Marvel, David M. Reif, Abraham Garcia, Catherine Lu, Michael T. Simonich, Justin G. Teeguarden, Robert L. Tanguay

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2017 Aug 15; 329: 148–157. Published online 2017 Jun 3. doi: 10.1016/j.taap.2017.05.033

PMCID:: PMC5539966

Abstract Article PDF–1.1M

Select item 543813216.

In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression

Gloria R. Garcia, Britton C. Goodale, Michelle W. Wiley, Jane K. La Du, David A. Hendrix, Robert L. Tanguay

Mol Pharmacol. 2017 Jun; 91(6): 609–619. Published online 2017 Jun. doi: 10.1124/mol.117.108233

PMCID:: PMC5438132

Abstract Article PDF–1.4M

Select item 541485517.

Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs

Anna C. Chlebowski, Gloria R. Garcia, Jane K. La Du, William H. Bisson, Lisa Truong, Staci L. Massey Simonich, Robert L. Tanguay

Toxicol Sci. 2017 May; 157(1): 246–259. Published online 2017 Feb 10. doi: 10.1093/toxsci/kfx035

PMCID:: PMC5414855

Abstract Article PDF–1.9M

Select item 523599018.

Developmental benzo[a]pyrene (B[a]P) exposure impacts larval behavior and impairs adult learning in zebrafish

Andrea L. Knecht, Lisa Truong, Michael T. Simonich, Robert L. Tanguay

Neurotoxicol Teratol. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: Neurotoxicol Teratol. 2017 Jan-Feb; 59: 27–34. Published online 2016 Oct 27. doi: 10.1016/j.ntt.2016.10.006

PMCID:: PMC5235990

Abstract Article PDF–1.0M

Select item 518793719.

Neurotoxicity of a Biopesticide Analog on Zebrafish Larvae at Nanomolar Concentrations

Ahmed Nasri, Audrey J. Valverde, Daniel B. Roche, Catherine Desrumaux, Philippe Clair, Hamouda Beyrem, Laurent Chaloin, Alain Ghysen, Véronique Perrier

Int J Mol Sci. 2016 Dec; 17(12): 2137. Published online 2016 Dec 19. doi: 10.3390/ijms17122137