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Select item 104431841.

The nuclear Argonaute HRDE-1 directs target gene re-localization and shuttles to nuage to promote small RNA-mediated inherited silencing

Yue-He Ding, Humberto J. Ochoa, Takao Ishidate, Masaki Shirayama, Craig C. Mello

Cell Rep. Author manuscript; available in PMC 2023 Aug 22.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112408. Published online 2023 Apr 20. doi: 10.1016/j.celrep.2023.112408

PMCID:: PMC10443184

Abstract Article PDF–2.6M

Select item 102020902.

A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans

Ilkin Aygün, Alicja Rzepczak, Takashi S. Miki

Genet Mol Biol. 2023; 46(2): e20220328. Published online 2023 May 15. doi: 10.1590/1678-4685-GMB-2022-0328

PMCID:: PMC10202090

Abstract Article PDF–3.7M

Select item 97984723.

Reprogramming the piRNA pathway for multiplexed and transgenerational gene silencing in C. elegans

Monika Priyadarshini, Julie Zhouli Ni, Amhed M. Vargas-Velazquez, Sam Guoping Gu, Christian Frøkjær-Jensen

Nat Methods. Author manuscript; available in PMC 2022 Dec 29.

Published in final edited form as: Nat Methods. 2022 Feb; 19(2): 187–194. Published online 2022 Feb 3. doi: 10.1038/s41592-021-01369-z

PMCID:: PMC9798472

Abstract Article PDF–4.2M

Select item 84500934.

Antisense ribosomal siRNAs inhibit RNA polymerase I-directed transcription in C. elegans

Shimiao Liao, Xiangyang Chen, Ting Xu, Qile Jin, Zongxiu Xu, Demin Xu, Xufei Zhou, Chengming Zhu, Shouhong Guang, Xuezhu Feng

Nucleic Acids Res. 2021 Sep 20; 49(16): 9194–9210. Published online 2021 Aug 7. doi: 10.1093/nar/gkab662

PMCID:: PMC8450093

Abstract Article PDF–3.3M

Select item 79951765.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 78868536.

Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans

Emiko Okabe, Masaharu Uno, Saya Kishimoto, Eisuke Nishida

Commun Biol. 2021; 4: 207. Published online 2021 Feb 16. doi: 10.1038/s42003-021-01692-3

PMCID:: PMC7886853

Abstract Article PDF–1.2M

Select item 77782637.

Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression

Jan Padeken, Stephen Methot, Peter Zeller, Colin E. Delaney, Veronique Kalck, Susan M. Gasser

Genes Dev. 2021 Jan 1; 35(1-2): 82–101. doi: 10.1101/gad.344234.120

PMCID:: PMC7778263

Abstract Article PDF–11M

Select item 77682658.

A Conserved NRDE-2/MTR-4 Complex Mediates Nuclear RNAi in Caenorhabditis elegans

Gang Wan, Jenny Yan, Yuhan Fei, Daniel J. Pagano, Scott Kennedy

Genetics. 2020 Dec; 216(4): 1071–1085. Published online 2020 Oct 14. doi: 10.1534/genetics.120.303631

PMCID:: PMC7768265

Abstract Article PDF–1.6M

Select item 73161389.

Germ Granules Coordinate RNA-based Epigenetic Inheritance Pathways

Anne E. Dodson, Scott Kennedy

Dev Cell. Author manuscript; available in PMC 2020 Sep 23.

Published in final edited form as: Dev Cell. 2019 Sep 23; 50(6): 704–715.e4. Published online 2019 Aug 8. doi: 10.1016/j.devcel.2019.07.025

PMCID:: PMC7316138

Abstract Article PDF–1.8M

Select item 658872410.

Chromatin Compaction by Small RNAs and the Nuclear RNAi Machinery in C. elegans

Brandon D. Fields, Scott Kennedy

Sci Rep. 2019; 9: 9030. Published online 2019 Jun 21. doi: 10.1038/s41598-019-45052-y

PMCID:: PMC6588724

Abstract Article PDF–1.2M

Select item 646646411.

Transgenerational Epigenetic Inheritance Is Revealed as a Multi-step Process by Studies of the SET-Domain Proteins SET-25 and SET-32

Rachel M Woodhouse, Alyson Ashe

Epigenet Insights. 2019; 12: 2516865719844214. Published online 2019 Apr 15. doi: 10.1177/2516865719844214

PMCID:: PMC6466464

Abstract Article PDF–648K

Select item 621659012.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 576430313.

lin-4 and the NRDE pathway are required to activate a transgenic lin-4 reporter but not the endogenous lin-4 locus in C. elegans

Alan L. Jiao, Daniel J. Foster, Julia Dixon, Frank J. Slack

PLoS One. 2018; 13(1): e0190766. Published online 2018 Jan 11. doi: 10.1371/journal.pone.0190766

PMCID:: PMC5764303

Abstract Article PDF–1.3M

Select item 427415314.

Endogenous Nuclear RNAi Mediates Behavioral Adaptation to Odor

Bi-Tzen Juang, Chen Gu, Linda Starnes, Francesca Palladino, Andrei Goga, Scott Kennedy, Noelle D. L'Etoile

Cell. Author manuscript; available in PMC 2014 Dec 22.

Published in final edited form as: Cell. 2013 Aug 29; 154(5): 1010–1022. doi: 10.1016/j.cell.2013.08.006

PMCID:: PMC4274153

Abstract Article PDF–1.3M

Select item 420566015.

Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations

Aisa Sakaguchi, Peter Sarkies, Matt Simon, Anna-Lisa Doebley, Leonard D. Goldstein, Ashley Hedges, Kohta Ikegami, Stacy M. Alvares, Liwei Yang, Jeannine R. LaRocque, Julie Hall, Eric A. Miska, Shawn Ahmed

Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41): E4323–E4331. Published online 2014 Sep 25. doi: 10.1073/pnas.1406131111