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Select item 101679951.

The dynamin GTPase mediates regenerative axonal fusion in Caenorhabditis elegans by regulating fusogen levels

Tarika Vijayaraghavan, Samiksha Dhananjay, Xue Yan Ho, Rosina Giordano-Santini, Massimo Hilliard, Brent Neumann

PNAS Nexus. 2023 May; 2(5): pgad114. Published online 2023 May 9. doi: 10.1093/pnasnexus/pgad114

PMCID:: PMC10167995

Abstract Article PDF–5.1M

Select item 89263322.

The metalloprotease ADM-4/ADAM17 promotes axonal repair

Xue Yan Ho, Sean Coakley, Rumelo Amor, Victor Anggono, Massimo A. Hilliard

Sci Adv. 2022 Mar; 8(11): eabm2882. Published online 2022 Mar 16. doi: 10.1126/sciadv.abm2882

PMCID:: PMC8926332

Abstract Article PDF–1.6M

Select item 81669033.

Cryptic genetic variation in a heat shock protein modifies the outcome of a mutation affecting epidermal stem cell development in C. elegans

Sneha L. Koneru, Mark Hintze, Dimitris Katsanos, Michalis Barkoulas

Nat Commun. 2021; 12: 3263. Published online 2021 May 31. doi: 10.1038/s41467-021-23567-1

PMCID:: PMC8166903

Abstract Article PDF–3.9M

Select item 81053894.

A role for the fusogen eff-1 in epidermal stem cell number robustness in Caenorhabditis elegans

Sneha L. Koneru, Fu Xiang Quah, Ritobrata Ghose, Mark Hintze, Nicola Gritti, Jeroen Sebastiaan van Zon, Michalis Barkoulas

Sci Rep. 2021; 11: 9787. Published online 2021 May 7. doi: 10.1038/s41598-021-88500-4

PMCID:: PMC8105389

Abstract Article PDF–12M

Select item 79017695.

The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response

Zhe Zhang, Shuo Luo, Guilherme Oliveira Barbosa, Meirong Bai, Thomas B. Kornberg, Dengke K. Ma

PLoS Genet. 2021 Feb; 17(2): e1009317. Published online 2021 Feb 1. doi: 10.1371/journal.pgen.1009317

PMCID:: PMC7901769

Abstract Article PDF–2.6M

Select item 70156886.

Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking

Zhe Zhang, Meirong Bai, Guilherme Oliveira Barbosa, Andrew Chen, Yuehua Wei, Shuo Luo, Xin Wang, Bingying Wang, Tatsuya Tsukui, Hao Li, Dean Sheppard, Thomas B. Kornberg, Dengke K. Ma

Sci Adv. 2020 Feb; 6(7): eaay7667. Published online 2020 Feb 12. doi: 10.1126/sciadv.aay7667

PMCID:: PMC7015688

Abstract Article PDF–844K

Select item 65080887.

dmd-3, a doublesex-related gene regulated by tra-1, governs sex-specific morphogenesis in C. elegans

D. Adam Mason, Jeremy S. Rabinowitz, Douglas S. Portman

Development. Author manuscript; available in PMC 2019 May 9.

Published in final edited form as: Development. 2008 Aug; 135(14): 2373–2382. Published online 2008 Jun 11. doi: 10.1242/dev.017046

PMCID:: PMC6508088

Abstract Article PDF–1.9M

Select item 64624468.

Disruption of RAB-5 Increases EFF-1 Fusogen Availability at the Cell Surface and Promotes the Regenerative Axonal Fusion Capacity of the Neuron

Casey Linton, M. Asrafuzzaman Riyadh, Xue Yan Ho, Brent Neumann, Rosina Giordano-Santini, Massimo A. Hilliard

J Neurosci. 2019 Apr 10; 39(15): 2823–2836. doi: 10.1523/JNEUROSCI.1952-18.2019

PMCID:: PMC6462446

Abstract Article PDF–4.0M

Select item 64426799.

Axon-Dependent Patterning and Maintenance of Somatosensory Dendritic Arbors

Nelson J. Ramirez-Suarez, Helen M. Belalcazar, Christopher J. Salazar, Burcu Beyaz, Benjamin Raja, Ken C.Q. Nguyen, Kevin Celestrin, Julius Fredens, Nils J. Færgeman, David H. Hall, Hannes E. Bülow

Dev Cell. Author manuscript; available in PMC 2020 Jan 28.

Published in final edited form as: Dev Cell. 2019 Jan 28; 48(2): 229–244.e4. Published online 2019 Jan 17. doi: 10.1016/j.devcel.2018.12.015

PMCID:: PMC6442679

Abstract Article PDF–1.6M

Select item 587613510.

EFF-1 fusogen promotes phagosome sealing during cell process clearance in C. elegans

Piya Ghose, Alina Rashid, Peter Insley, Meera Trivedi, Pavak Shah, Anupriya Singhal, Yun Lu, Zhirong Bao, Shai Shaham

Nat Cell Biol. Author manuscript; available in PMC 2018 Sep 19.

Published in final edited form as: Nat Cell Biol. 2018 Apr; 20(4): 393–399. Published online 2018 Mar 19. doi: 10.1038/s41556-018-0068-5

PMCID:: PMC5876135

Abstract Article PDF–1.3M

Select item 576958811.

Dynein and EFF-1 control dendrite morphology by regulating the localization pattern of SAX-7 in epidermal cells

Ting Zhu, Xing Liang, Xiang-Ming Wang, Kang Shen

J Cell Sci. 2017 Dec 1; 130(23): 4063–4071. doi: 10.1242/jcs.201699

PMCID:: PMC5769588

Abstract Article

Select item 570327412.

let-7 miRNA controls CED-7 homotypic adhesion and EFF-1–mediated axonal self-fusion to restore touch sensation following injury

Atrayee Basu, Shirshendu Dey, Dharmendra Puri, Nilanjana Das Saha, Vidur Sabharwal, Pankajam Thyagarajan, Prerna Srivastava, Sandhya Padmanabhan Koushika, Anindya Ghosh-Roy

Proc Natl Acad Sci U S A. 2017 Nov 21; 114(47): E10206–E10215. Published online 2017 Nov 6. doi: 10.1073/pnas.1704372114