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Select item 93600151.

IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii

Sambamurthy Chandrasekaran, Joshua A. Kochanowsky, Emily F. Merritt, Joseph S. Lagas, Ayesha Swannigan, Anita A. Koshy

Nat Commun. 2022; 13: 4605. Published online 2022 Aug 8. doi: 10.1038/s41467-022-32225-z

PMCID:: PMC9360015

Abstract Article PDF–4.2M

Select item 88139122.

The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice

Shelbi Christgen, David Place, Min Zheng, Benoit Briard, Masahiro Yamamoto, Thirumala-Devi Kanneganti

Eur J Immunol. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Eur J Immunol. 2022 Feb; 52(2): 285–296. Published online 2021 Nov 9. doi: 10.1002/eji.202149305

PMCID:: PMC8813912

Abstract Article PDF–1.5M

Select item 86866903.

Genome Instability Independent of Type I Interferon Signaling Drives Neuropathology Caused by Impaired Ribonucleotide Excision Repair

Aditi, Susanna M. Downing, Patrick A. Schreiner, Young Don Kwak, Yang Li, Timothy I. Shaw, Helen R. Russell, Peter J. McKinnon

Neuron. Author manuscript; available in PMC 2022 Dec 15.

Published in final edited form as: Neuron. 2021 Dec 15; 109(24): 3962–3979.e6. Published online 2021 Oct 15. doi: 10.1016/j.neuron.2021.09.040

PMCID:: PMC8686690

Abstract Article PDF–4.1M

Select item 85192654.

Murine Irgm Paralogs Regulate Nonredundant Functions To Execute Host Defense to Toxoplasma gondii

Jacob Dockterman, Brian E. Fee, Gregory A. Taylor, Jörn Coers

Infect Immun. 2021 Nov; 89(11): e00202-21. Prepublished online 2021 Aug 2. Published online 2021 Oct 15. doi: 10.1128/IAI.00202-21

PMCID:: PMC8519265

Abstract Article PDF–2.2M

Select item 82002985.

Cell-autonomous Toxoplasma killing program requires Irgm2 but not its microbe vacuolar localization

Ariel Pradipta, Miwa Sasai, Kou Motani, Ji Su Ma, Youngae Lee, Hidetaka Kosako, Masahiro Yamamoto

Life Sci Alliance. 2021 Jul; 4(7): e202000960. Published online 2021 Jun 2. doi: 10.26508/lsa.202000960

PMCID:: PMC8200298

Abstract Article PDF–2.9M

Select item 76452546.

Ryan Finethy, Jacob Dockterman, Miriam Kutsch, Nichole Orench‐Rivera, Graham D Wallace, Anthony S Piro, Sarah Luoma, Arun K Haldar, Seungmin Hwang, Jennifer Martinez, Meta J Kuehn, Gregory A Taylor, Jörn Coers

EMBO Rep. 2020 Nov 5; 21(11): e50830. Published online 2020 Oct 30. doi: 10.15252/embr.202050830

PMCID:: PMC7645254

Abstract Article PDF–1.1M

Select item 68129327.

The ROP16_III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival

Shraddha Tuladhar, Joshua A. Kochanowsky, Apoorva Bhaskara, Yarah Ghotmi, Sambamurthy Chandrasekaran, Anita A. Koshy

PLoS Pathog. 2019 Oct; 15(10): e1007856. Published online 2019 Oct 24. doi: 10.1371/journal.ppat.1007856

PMCID:: PMC6812932

Abstract Article PDF–4.6M

Select item 62980408.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 53385559.

Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems

Eric M. Feeley, Danielle M. Pilla-Moffett, Erin E. Zwack, Anthony S. Piro, Ryan Finethy, Joseph P. Kolb, Jennifer Martinez, Igor E. Brodsky, Jörn Coers

Proc Natl Acad Sci U S A. 2017 Feb 28; 114(9): E1698–E1706. Published online 2017 Feb 13. doi: 10.1073/pnas.1615771114

PMCID:: PMC5338555

Abstract Article PDF–1.2M

Select item 482164910.

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation

David Langlais, Luis B. Barreiro, Philippe Gros

J Exp Med. 2016 Apr 4; 213(4): 585–603. doi: 10.1084/jem.20151764

PMCID:: PMC4821649

Abstract Article PDF–3.1M

Select item 436343411.

IRGM3 Contributes to Immunopathology and Is Required for Differentiation of Antigen-Specific Effector CD8⁺ T Cells in Experimental Cerebral Malaria

Jintao Guo, James A. McQuillan, Belinda Yau, Gregory S. Tullo, Carole A. Long, Patrick Bertolino, Ben Roediger, Wolfgang Weninger, Gregory A. Taylor, Nicholas H. Hunt, Helen J. Ball, Andrew J. Mitchell

Infect Immun. 2015 Apr; 83(4): 1406–1417. Prepublished online 2015 Feb 2. Published online 2015 Mar 17. doi: 10.1128/IAI.02701-14

PMCID:: PMC4363434

Abstract Article PDF–464K

Select item 421479912.

Identification of the Microsporidian Encephalitozoon cuniculi as a New Target of the IFNγ-Inducible IRG Resistance System

Marialice da Fonseca Ferreira-da-Silva, Helen Maria Springer-Frauenhoff, Wolfgang Bohne, Jonathan C. Howard

PLoS Pathog. 2014 Oct; 10(10): e1004449. Published online 2014 Oct 30. doi: 10.1371/journal.ppat.1004449

Correction in:: PLoS Pathog. 2014 Dec; 10(12): e1004590.

PMCID:: PMC4214799

Abstract Article PDF–2.0M

Select item 400325113.

IFN-inducible p47 GTPases display differential responses to Schistosoma japonicum acute infection

Xuesong Chen, Xiaotang Du, Meijuan Zhang, Donghui Zhang, Minjun Ji, Guanling Wu

Cell Mol Immunol. 2010 Jan; 7(1): 69–76. Published online 2009 Dec 23. doi: 10.1038/cmi.2009.100

PMCID:: PMC4003251

Abstract Article PDF–986K

Select item 400084814.

Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS

Danielle M. Pilla, Jon A. Hagar, Arun K. Haldar, Ashley K. Mason, Daniel Degrandi, Klaus Pfeffer, Robert K. Ernst, Masahiro Yamamoto, Edward A. Miao, Jörn Coers

Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16): 6046–6051. Published online 2014 Apr 8. doi: 10.1073/pnas.1321700111

PMCID:: PMC4000848

Abstract Article PDF–859K

Select item 369100615.

Zhen Liu, Huifang M. Zhang, Ji Yuan, Xin Ye, Gregory A. Taylor, Decheng Yang

Cell Microbiol. Author manuscript; available in PMC 2013 Jun 24.

Published in final edited form as: Cell Microbiol. 2012 Jan; 14(1): 133–146. Published online 2011 Nov 10. doi: 10.1111/j.1462-5822.2011.01708.x

PMCID:: PMC3691006

Abstract Article PDF–4.1M

Select item 369095016.

CD4⁺ T cells are necessary and sufficient to confer protection against C. trachomatis infection in the murine upper genital tract

David C. Gondek, Andrew J. Olive, Georg Stary, Michael N. Starnbach

J Immunol. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: J Immunol. 2012 Sep 1; 189(5): 2441–2449. Published online 2012 Aug 1. doi: 10.4049/jimmunol.1103032

PMCID:: PMC3690950

Abstract Article PDF–3.0M

Select item 368173717.

IRG and GBP Host Resistance Factors Target Aberrant, “Non-self” Vacuoles Characterized by the Missing of “Self” IRGM Proteins

Arun K. Haldar, Hector A. Saka, Anthony S. Piro, Joe Dan Dunn, Stanley C. Henry, Gregory A. Taylor, Eva M. Frickel, Raphael H. Valdivia, Jörn Coers

PLoS Pathog. 2013 Jun; 9(6): e1003414. Published online 2013 Jun 13. doi: 10.1371/journal.ppat.1003414

PMCID:: PMC3681737

Abstract Article PDF–5.1M

Select item 363597518.

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii

Elizabeth M. Selleck, Sarah J. Fentress, Wandy L. Beatty, Daniel Degrandi, Klaus Pfeffer, Herbert W. Virgin, IV, John D. MacMicking, L. David Sibley

PLoS Pathog. 2013 Apr; 9(4): e1003320. Published online 2013 Apr 25. doi: 10.1371/journal.ppat.1003320

PMCID:: PMC3635975

Abstract Article PDF–19M

Select item 357241019.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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