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Select item 110879641.

Mst4, a novel cardiac STRIPAK complex–associated kinase, regulates cardiomyocyte growth and survival and is upregulated in human cardiomyopathy

Matthias Eden, Marius Leye, Justus Hahn, Emanuel Heilein, Marcin Luzarowski, Bill Völschow, Christin Tannert, Samuel Sossalla, Carlota Lucena-Porcel, Derk Frank, Norbert Frey

J Biol Chem. 2024 May; 300(5): 107255. Published online 2024 Apr 3. doi: 10.1016/j.jbc.2024.107255

PMCID:: PMC11087964

Abstract Article PDF–4.4M

Select item 105389882.

Torsional and strain dysfunction precede overt heart failure in a mouse model of dilated cardiomyopathy pathogenesis

Joshua B. Holmes, Madeleine E. Lemieux, Julian E. Stelzer

Am J Physiol Heart Circ Physiol. 2023 Sep 1; 325(3): H449–H467. Published online 2023 Jul 7. doi: 10.1152/ajpheart.00130.2023

PMCID:: PMC10538988

Abstract Article

Select item 84463383.

ACAA2 is a Ligand-dependent Coactivator for Thyroid Hormone Receptor β1

Wesley Wang, Dolena Ledee

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 22.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Oct 22; 576: 15–21. Published online 2021 Aug 28. doi: 10.1016/j.bbrc.2021.08.073

PMCID:: PMC8446338

Abstract Article PDF–830K

Select item 84058074.

Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy

Niels Grote Beverborg, Daniela Später, Ralph Knöll, Alejandro Hidalgo, Steve T. Yeh, Zaher Elbeck, Herman H. W. Silljé, Tim R. Eijgenraam, Humam Siga, Magdalena Zurek, Malin Palmér, Susanne Pehrsson, Tamsin Albery, Nils Bomer, Martijn F. Hoes, Cornelis J. Boogerd, Michael Frisk, Eva van Rooij, Sagar Damle, William E. Louch, Qing-Dong Wang, Regina Fritsche-Danielson, Kenneth R. Chien, Kenny M. Hansson, Adam E. Mullick, Rudolf A. de Boer, Peter van der Meer

Nat Commun. 2021; 12: 5180. Published online 2021 Aug 30. doi: 10.1038/s41467-021-25439-0

PMCID:: PMC8405807

Abstract Article PDF–2.8M

Select item 82256745.

Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy

Davy Vanhoutte, Tobias G. Schips, Alexander Vo, Kelly M. Grimes, Tanya A. Baldwin, Matthew J. Brody, Federica Accornero, Michelle A. Sargent, Jeffery D. Molkentin

Nat Commun. 2021; 12: 3928. Published online 2021 Jun 24. doi: 10.1038/s41467-021-24215-4

PMCID:: PMC8225674

Abstract Article PDF–5.9M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 71575857.

Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development

Megha Agarwal, Akashi Sharma, Pankaj Kumar, Amit Kumar, Anushree Bharadwaj, Masum Saini, Gabrielle Kardon, Sam J. Mathew

Development. 2020 Apr 1; 147(7): dev184507. Published online 2020 Apr 6. doi: 10.1242/dev.184507

PMCID:: PMC7157585

Abstract Article

Select item 62319758.

Sarcomere-based genetic enhancement of systolic cardiac function in a murine model of dilated cardiomyopathy

Jiayang Li, Kenneth S. Gresham, Ranganath Mamidi, Chang Yoon Doh, Xiaoping Wan, Isabelle Deschenes, Julian E. Stelzer

Int J Cardiol. Author manuscript; available in PMC 2019 Dec 15.

Published in final edited form as: Int J Cardiol. 2018 Dec 15; 273: 168–176. Published online 2018 Sep 21. doi: 10.1016/j.ijcard.2018.09.073

PMCID:: PMC6231975

Abstract Article PDF–970K

Select item 62020519.

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy

Catherine A Makarewich, Amir Z Munir, Gabriele G Schiattarella, Svetlana Bezprozvannaya, Olga N Raguimova, Ellen E Cho, Alexander H Vidal, Seth L Robia, Rhonda Bassel-Duby, Eric N Olson

eLife. 2018; 7: e38319. Published online 2018 Oct 9. doi: 10.7554/eLife.38319

PMCID:: PMC6202051

Abstract Article PDF–4.3M

Select item 613949310.

Cysteine- and glycine-rich protein 3 regulates glucose homeostasis in skeletal muscle

Angelina Hernandez-Carretero, Natalie Weber, Samuel A. LaBarge, Veronika Peterka, Nhu Y Thi Doan, Simon Schenk, Olivia Osborn

Am J Physiol Endocrinol Metab. 2018 Aug 1; 315(2): E267–E278. Published online 2018 Apr 10. doi: 10.1152/ajpendo.00435.2017

PMCID:: PMC6139493

Abstract Article

Select item 611745311.

Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion

Mehroz Ehsan, Matthew Kelly, Charlotte Hooper, Arash Yavari, Julia Beglov, Mohamed Bellahcene, Kirandeep Ghataorhe, Giulia Poloni, Anuj Goel, Theodosios Kyriakou, Karin Fleischanderl, Elisabeth Ehler, Eugene Makeyev, Stephan Lange, Houman Ashrafian, Charles Redwood, Benjamin Davies, Hugh Watkins, Katja Gehmlich

J Mol Cell Cardiol. 2018 Aug; 121: 287–296. doi: 10.1016/j.yjmcc.2018.07.248

PMCID:: PMC6117453

Abstract Article PDF–2.8M

Select item 598760612.

Gene expression profiling in the developing secondary palate in the absence of Tbx1 function

Maria Zoupa, Guilherme Machado Xavier, Stephanie Bryan, Ioannis Theologidis, Matthew Arno, Martyn T. Cobourne

BMC Genomics. 2018; 19: 429. Published online 2018 Jun 4. doi: 10.1186/s12864-018-4782-y

PMCID:: PMC5987606

Abstract Article PDF–2.6M

Select item 580929413.

Increased cardiac arrhythmogenesis associated with gap junction remodeling with upregulation of RNA binding protein FXR1

Miensheng Chu, Stefanie Mares Novak, Cathleen Cover, Anne A. Wang, Ikeotunye Royal Chinyere, Elizabeth B. Juneman, Daniela C. Zarnescu, Pak Kin Wong, Carol C. Gregorio

Circulation. Author manuscript; available in PMC 2019 Feb 6.

Published in final edited form as: Circulation. 2018 Feb 6; 137(6): 605–618. Published online 2017 Nov 3. doi: 10.1161/CIRCULATIONAHA.117.028976

PMCID:: PMC5809294

Abstract Article PDF–1.6M

Select item 579902314.

Chemical cross-linking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue

Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Andrew Keller, Rong Tian, James E. Bruce

Cell Syst. Author manuscript; available in PMC 2019 Jan 24.

Published in final edited form as: Cell Syst. 2018 Jan 24; 6(1): 136–141.e5. Published online 2017 Nov 29. doi: 10.1016/j.cels.2017.10.017

PMCID:: PMC5799023

Abstract Article PDF–730K

Select item 560238015.

The novel cardiac z-disc protein CEFIP regulates cardiomyocyte hypertrophy by modulating calcineurin signaling

Franziska Dierck, Christian Kuhn, Claudia Rohr, Susanne Hille, Julia Braune, Samuel Sossalla, Sibylle Molt, Peter F. M. van der Ven, Dieter O. Fürst, Norbert Frey

J Biol Chem. 2017 Sep 15; 292(37): 15180–15191. Published online 2017 Jul 17. doi: 10.1074/jbc.M117.786764

PMCID:: PMC5602380

Abstract Article PDF–3.1M

Select item 553140616.

Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy

Xi Fang, Julius Bogomolovas, Tongbin Wu, Wei Zhang, Canzhao Liu, Jennifer Veevers, Matthew J. Stroud, Zhiyuan Zhang, Xiaolong Ma, Yongxin Mu, Dieu-Hung Lao, Nancy D. Dalton, Yusu Gu, Celine Wang, Michael Wang, Yan Liang, Stephan Lange, Kunfu Ouyang, Kirk L. Peterson, Sylvia M. Evans, Ju Chen

J Clin Invest. 2017 Aug 1; 127(8): 3189–3200. Published online 2017 Jul 24. doi: 10.1172/JCI94310

PMCID:: PMC5531406

Abstract Article PDF–2.7M

Select item 550971417.

Mitsugumin 29 regulates t-tubule architecture in the failing heart

Robert N. Correll, Jeffrey M. Lynch, Tobias G. Schips, Vikram Prasad, Allen J. York, Michelle A. Sargent, Didier X. P. Brochet, Jianjie Ma, Jeffery D. Molkentin

Sci Rep. 2017; 7: 5328. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05284-2

PMCID:: PMC5509714

Abstract Article PDF–1.7M

Select item 503038718.

Small mammalian animal models of heart disease

Paula Camacho, Huimin Fan, Zhongmin Liu, Jia-Qiang He

Am J Cardiovasc Dis. 2016; 6(3): 70–80. Published online 2016 Sep 15.

PMCID:: PMC5030387

Abstract Article PDF–288K

Select item 499035619.

The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly

Stuart J. Smith, Norma Towers, José W. Saldanha, Catherine A. Shang, S. Radma Mahmood, William R. Taylor, Timothy J. Mohun

Dev Biol. 2016 Aug 15; 416(2): 373–388. doi: 10.1016/j.ydbio.2016.05.006

PMCID:: PMC4990356

Abstract Article

Select item 493134320.

MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy

Stephan Lange, Katja Gehmlich, Alexander S. Lun, Jordan Blondelle, Charlotte Hooper, Nancy D. Dalton, Erika A. Alvarez, Xiaoyu Zhang, Marie-Louise Bang, Yama A. Abassi, Cristobal G. dos Remedios, Kirk L. Peterson, Ju Chen, Elisabeth Ehler

Nat Commun. 2016; 7: 12120. Published online 2016 Jun 29. doi: 10.1038/ncomms12120

PMCID:: PMC4931343

Abstract Article PDF–2.2M

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