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Items: 1 to 20 of 124

1.
Selective regulation of a defined subset of inflammatory and immunoregulatory genes by an NF-κB p50–IκBζ pathway
Allison E. Daly, George Yeh, Sofia Soltero, Stephen T. Smale
Genes Dev. 2024 Jun 1; 38(11-12): 536–553. doi: 10.1101/gad.351630.124
PMCID:
PMC11293394
AbstractArticlePDF–9.5M
2.
Tonic TNF conditioning of macrophages safeguards stimulus‐specific inflammatory responses
Stefanie Luecke, Adewunmi Adelaja, Xiaolu Guo, Supriya Sen, Roberto Spreafico, Apeksha Singh, Yi Liu, Brooks Taylor, Jessica Diaz, Quen Cheng, Alexander Hoffmann
EMBO Rep. 2023 Jul; 24(7): e55986. Published online 2023 May 22. doi: 10.15252/embr.202255986
PMCID:
PMC10328066
AbstractArticlePDF–6.1M
3.
HDAC5-Mediated Acetylation of p100 Suppresses Its Processing
Jianqi Wang, Shuainan Wu, Lu Liu, Ying Pang, Zhaobao Li, Hong Mu
Int Dent J. 2023 Jun; 73(3): 387–394. Published online 2022 Sep 23. doi: 10.1016/j.identj.2022.08.007
PMCID:
PMC10213722
AbstractArticlePDF–1.7M
4.
Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa
Stamatia Papoutsopoulou, Joseph Tang, Ahmed H. Elramli, Jonathan M. Williams, Nitika Gupta, Felix I. Ikuomola, Raheleh Sheibani-Tezerji, Mohammad T. Alam, Juan R. Hernández-Fernaud, Jorge H. Caamaño, Chris S. Probert, Werner Muller, Carrie A. Duckworth, D. Mark Pritchard
Am J Physiol Gastrointest Liver Physiol. 2022 Oct 1; 323(4): G306–G317. Published online 2022 Aug 2. doi: 10.1152/ajpgi.00037.2022
PMCID:
PMC9485003
AbstractArticle
5.
TRAF2 regulates T cell immunity by maintaining a Tpl2-ERK survival signaling axis in effector and memory CD8 T cells
Xiaoping Xie, Lele Zhu, Zuliang Jie, Yanchuan Li, Meidi Gu, Xiaofei Zhou, Hui Wang, Jae-Hoon Chang, Chun-Jung Ko, Xuhong Cheng, Shao-Cong Sun
Cell Mol Immunol. 2021 Sep; 18(9): 2262–2274. Published online 2020 Nov 17. doi: 10.1038/s41423-020-00583-7
PMCID:
PMC8429472
AbstractArticlePDF–4.3M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module
Meenakshi Chawla, Tapas Mukherjee, Alvina Deka, Budhaditya Chatterjee, Uday Aditya Sarkar, Amit K. Singh, Saurabh Kedia, Josephine Lum, Manprit Kaur Dhillon, Balaji Banoth, Subhra K. Biswas, Vineet Ahuja, Soumen Basak
Proc Natl Acad Sci U S A. 2021 Jun 22; 118(25): e2024828118. Published online 2021 Jun 21. doi: 10.1073/pnas.2024828118
PMCID:
PMC8237674
AbstractArticlePDF–2.0M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells
Serkan I. Göktuna, Ozge Canli, Julia Bollrath, Alexander A. Fingerle, David Horst, Michaela A. Diamanti, Charles Pallangyo, Moritz Bennecke, Tim Nebelsiek, Arun K. Mankan, Roland Lang, David Artis, Yinling Hu, Thomas Patzelt, Jürgen Ruland, Thomas Kirchner, M. Mark Taketo, Alain Chariot, Melek C. Arkan, Florian R. Greten
Cell Rep. Author manuscript; available in PMC 2020 Nov 19.
Published in final edited form as: Cell Rep. 2014 Jun 26; 7(6): 1914–1925. Published online 2014 May 29. doi: 10.1016/j.celrep.2014.05.006
Correction in:
Cell Rep. 2022 Mar 1; 38(9): 110471.
PMCID:
PMC7676455
AbstractArticlePDF–2.1M
10.
Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility
Rushika C. Wirasinha, Ainsley R. Davies, Monika Srivastava, Julie M. Sheridan, Xavier Y.X. Sng, Ottavia M. Delmonte, Kerry Dobbs, Khai L. Loh, Lisa A. Miosge, Cindy Eunhee Lee, Rochna Chand, Anna Chan, Jin Yan Yap, Michael D. Keller, Karin Chen, Jamie Rossjohn, Nicole L. La Gruta, Carola G. Vinuesa, Hugh H. Reid, Michail S. Lionakis, Luigi D. Notarangelo, Daniel H.D. Gray, Christopher C. Goodnow, Matthew C. Cook, Stephen R. Daley
J Exp Med. 2021 Feb 1; 218(2): e20200476. Published online 2020 Oct 27. doi: 10.1084/jem.20200476
PMCID:
PMC7595743
AbstractArticlePDF–7.4M
11.
TRAF3 acts as a checkpoint of B cell receptor signaling to control antibody class switch recombination and anergy
Zhangguo Chen, Alexandra Krinsky, Rachel A. Woolaver, Xiaoguang Wang, Samantha M.Y. Chen, Vince Popolizio, Ping Xie, Jing H Wang
J Immunol. Author manuscript; available in PMC 2021 Aug 1.
Published in final edited form as: J Immunol. 2020 Aug 1; 205(3): 830–841. Published online 2020 Jun 26. doi: 10.4049/jimmunol.2000322
PMCID:
PMC7369235
AbstractArticlePDF–1.3M
12.
Avian Reticuloendotheliosis Viral Oncogene Related B Regulates Lymphatic Endothelial Cells during Vessel Maturation and Is Required for Lymphatic Vessel Function in Adult Mice
Qianqian Liang, Li Zhang, Ronald W. Wood, Rui-Cheng Ji, Brendan F. Boyce, Edward.M. Schwarz, Yongjun Wang, Lianping Xing
Am J Pathol. 2019 Dec; 189(12): 2516–2530. doi: 10.1016/j.ajpath.2019.08.009
PMCID:
PMC6893922
AbstractArticlePDF–2.7M
13.
NF-κB2 signalling in enteroids modulates enterocyte responses to secreted factors from bone marrow-derived dendritic cells
Lauren G. Jones, Andra Vaida, Louise M. Thompson, Felix I. Ikuomola, Jorge H. Caamaño, Michael D. Burkitt, Fabio Miyajima, Jonathan M. Williams, Barry J. Campbell, D. Mark Pritchard, Carrie A. Duckworth
Cell Death Dis. 2019 Dec; 10(12): 896. Published online 2019 Nov 26. doi: 10.1038/s41419-019-2129-5
PMCID:
PMC6879761
AbstractArticlePDF–2.2M
14.
Persistent Activation of NF-κB in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage
Andrea Sau, Rosanna Lau, Miguel A. Cabrita, Emma Nolan, Peter A. Crooks, Jane E. Visvader, M.A. Christine Pratt
Cell Stem Cell. Author manuscript; available in PMC 2019 Nov 12.
Published in final edited form as: Cell Stem Cell. 2016 Jul 7; 19(1): 52–65. Published online 2016 Jun 9. doi: 10.1016/j.stem.2016.05.003
PMCID:
PMC6850408
AbstractArticlePDF–1.2M
15.
RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells
Nico Andreas, Maria Potthast, Anna-Lena Geiselhöringer, Garima Garg, Renske de Jong, Julia Riewaldt, Dennis Russkamp, Marc Riemann, Jean-Philippe Girard, Simon Blank, Karsten Kretschmer, Carsten Schmidt-Weber, Thomas Korn, Falk Weih, Caspar Ohnmacht
J Immunol. 2019 Nov 15; 203(10): 2602–2613. Published online 2019 Oct 2. doi: 10.4049/jimmunol.1801530
PMCID:
PMC6826119
AbstractArticlePDF–1.4M
16.
Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization
Yanchuan Li, Jin-Young Yang, Xiaoping Xie, Zuliang Jie, Lingyun Zhang, Jianhong Shi, Daniel Lin, Meidi Gu, Xiaofei Zhou, Haiyan S. Li, Stephanie S. Watowich, Antrix Jain, Sung Yun Jung, Jun Qin, Xuhong Cheng, Shao-Cong Sun
Cell Res. 2019 Jun; 29(6): 474–485. Published online 2019 May 13. doi: 10.1038/s41422-019-0174-3
PMCID:
PMC6796864
AbstractArticlePDF–4.8M
17.
Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
Yuzhu Hou, Hua Liang, Enyu Rao, Wenxin Zheng, Xiaona Huang, Liufu Deng, Yuan Zhang, Xinshuang Yu, Meng Xu, Helena Mauceri, Ainhoa Arina, Ralph R. Weichselbaum, Yang-Xin Fu
Immunity. Author manuscript; available in PMC 2019 Oct 3.
Published in final edited form as: Immunity. 2018 Sep 18; 49(3): 490–503.e4. Published online 2018 Aug 28. doi: 10.1016/j.immuni.2018.07.008
PMCID:
PMC6775781
AbstractArticlePDF–1.0M
18.
Role of NF-kappaB2-p100 in regulatory T cell homeostasis and activation
Atika Dhar, Meenakshi Chawla, Somdeb Chattopadhyay, Neelam Oswal, Danish Umar, Suman Gupta, Vineeta Bal, Satyajit Rath, Anna George, G. Aneeshkumar Arimbasseri, Soumen Basak
Sci Rep. 2019; 9: 13867. Published online 2019 Sep 25. doi: 10.1038/s41598-019-50454-z
PMCID:
PMC6761191
AbstractArticlePDF–2.8M
19.
LSD1 cooperates with non-canonical NF-κB signaling to regulate marginal zone B cell development
Robert R. Haines, Christopher D. Scharer, Jenna L. Lobby, Jeremy M. Boss
J Immunol. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: J Immunol. 2019 Oct 1; 203(7): 1867–1881. Published online 2019 Sep 6. doi: 10.4049/jimmunol.1900654
PMCID:
PMC6761012
AbstractArticlePDF–3.7M
20.
Inactivation of NF-κB2 (p52) restrains hepatic glucagon response via preserving PDE4B induction
Wen-Song Zhang, An Pan, Xu Zhang, Ang Ying, Gaoxiang Ma, Bao-Lin Liu, Lian-Wen Qi, Qun Liu, Ping Li
Nat Commun. 2019; 10: 4303. Published online 2019 Sep 20. doi: 10.1038/s41467-019-12351-x
PMCID:
PMC6754499
AbstractArticlePDF–1.6M

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