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Items: 1 to 20 of 29

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism
Shotaro Uehara, Yuichi Iida, Miyuki Ida-Tanaka, Motohito Goto, Kenji Kawai, Masafumi Yamamoto, Yuichiro Higuchi, Satoshi Ito, Riichi Takahashi, Hidetaka Kamimura, Mamoru Ito, Hiroshi Yamazaki, Mitsuo Oshimura, Yasuhiro Kazuki, Hiroshi Suemizu
Sci Rep. 2022; 12: 14907. Published online 2022 Sep 1. doi: 10.1038/s41598-022-19242-0
PMCID:
PMC9437039
AbstractArticlePDF–2.0M
3.
Bmal1 regulates circadian expression of cytochrome P450 3a11 and drug metabolism in mice
Yanke Lin, Shuai Wang, Ziyue Zhou, Lianxia Guo, Fangjun Yu, Baojian Wu
Commun Biol. 2019; 2: 378. Published online 2019 Oct 16. doi: 10.1038/s42003-019-0607-z
PMCID:
PMC6795895
AbstractArticlePDF–1.9M
4.
High fat diet induced obesity is mitigated in Cyp3a-null female mice
Ramiya Kumar, Elizabeth J. Litoff, W. Tyler Boswell, William S. Baldwin
Chem Biol Interact. Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: Chem Biol Interact. 2018 Jun 1; 289: 129–140. Published online 2018 May 5. doi: 10.1016/j.cbi.2018.05.001
PMCID:
PMC6717702
AbstractArticlePDF–1.5M
5.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
6.
Sterol 27-hydroxylase gene dosage and the antiatherosclerotic effect of Rifampicin in mice
Line Zurkinden, Dmitri Sviridov, Bruno Vogt, Geneviève Escher
Biosci Rep. 2018 Feb 28; 38(1): BSR20171162. Prepublished online 2017 Nov 30. Published online 2018 Jan 25. doi: 10.1042/BSR20171162
PMCID:
PMC5784176
AbstractArticlePDF–2.8M
7.
Effect of Naringenin, Quercetin, and Sesamin on Xenobiotica-Metabolizing CYP1A and CYP3A in Mice Offspring after Maternal Exposure to Persistent Organic Pollutants
Nadezhda Pilipenko, Erik Ropstad, Ruth Halsne, Galia Zamaratskaia
Biomed Res Int. 2017; 2017: 8472312. Published online 2017 May 8. doi: 10.1155/2017/8472312
PMCID:
PMC5439065
AbstractArticlePDF–855K
8.
Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia
Shujuan Chen, Wenqi Lu, Mei-Fei Yueh, Eva Rettenmeier, Miao Liu, Miles Paszek, Johan Auwerx, Ruth T. Yu, Ronald M. Evans, Kepeng Wang, Michael Karin, Robert H. Tukey
Proc Natl Acad Sci U S A. 2017 Feb 21; 114(8): E1432–E1440. Published online 2017 Feb 6. doi: 10.1073/pnas.1700232114
Correction in:
Proc Natl Acad Sci U S A. 2017 May 16; 114(20): E4115.
PMCID:
PMC5338369
AbstractArticlePDF–1.5M
9.
Schisandrol B Protects Against Acetaminophen-Induced Hepatotoxicity by Inhibition of CYP-Mediated Bioactivation and Regulation of Liver Regeneration
Yiming Jiang, Xiaomei Fan, Ying Wang, Pan Chen, Hang Zeng, Huasen Tan, Frank J. Gonzalez, Min Huang, Huichang Bi
Toxicol Sci. 2015 Jan; 143(1): 107–115. Published online 2014 Oct 14. doi: 10.1093/toxsci/kfu216
PMCID:
PMC4334815
AbstractArticlePDF–822K
10.
Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis
Craig D. Fisher, Jonathan P. Jackson, Andrew J. Lickteig, Lisa M. Augustine, Nathan J. Cherrington
Arch Toxicol. Author manuscript; available in PMC 2015 Jan 14.
Published in final edited form as: Arch Toxicol. 2008 Dec; 82(12): 959–964. Published online 2008 May 17. doi: 10.1007/s00204-008-0312-z
PMCID:
PMC4294556
AbstractArticlePDF–379K
11.
Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment
Asha Seth, Jianming Ye, Nanjia Yu, Fanny Guez, David C. Bedford, Geoffrey A. Neale, Sabine Cordi, Paul K. Brindle, Frederic P. Lemaigre, Klaus H. Kaestner, Beatriz Sosa-Pineda
Development. 2014 Feb 1; 141(3): 538–547. doi: 10.1242/dev.099481
PMCID:
PMC3899812
AbstractArticle
12.
Downregulation of Mouse Hepatic CYP3A Protein by 3-Methylcholanthrene Does Not Require Cytochrome P450-Dependent Metabolism
Chunja Lee, Xinxin Ding, David S. Riddick
Drug Metab Dispos. 2013 Oct; 41(10): 1782–1786. Published online 2013 Oct. doi: 10.1124/dmd.113.052993
PMCID:
PMC3781373
AbstractArticlePDF–185K
13.
Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver
Mari Hashimoto, Kaoru Kobayashi, Mio Watanabe, Yasuhiro Kazuki, Shoko Takehara, Asumi Inaba, Shin-ichiro Nitta, Naoto Senda, Mitsuo Oshimura, Kan Chiba
J Lipid Res. 2013 Aug; 54(8): 2060–2068. doi: 10.1194/jlr.M033464
PMCID:
PMC3708357
AbstractArticlePDF–623K
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
Impact of lactobacilli on orally acquired listeriosis
Cristel Archambaud, Marie-Anne Nahori, Guillaume Soubigou, Christophe Bécavin, Laure Laval, Pierre Lechat, Tamara Smokvina, Philippe Langella, Marc Lecuit, Pascale Cossart
Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41): 16684–16689. Published online 2012 Sep 24. doi: 10.1073/pnas.1212809109
PMCID:
PMC3478606
AbstractArticlePDF–772K
16.
Opposing Regulation of Cytochrome P450 Expression by CAR and PXR in Hypothyroid Mice
Young Joo Park, Eun Kyung Lee, Yoon Kwang Lee, Do Joon Park, Hak Chul Jang, David D. Moore
Toxicol Appl Pharmacol. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2012 Sep 1; 263(2): 131–137. Published online 2012 Apr 3. doi: 10.1016/j.taap.2012.03.017
PMCID:
PMC3399920
AbstractArticlePDF–2.4M
17.
Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2
Irina M. Bochkis, Jonathan Schug, Diana Z. Ye, Svitlana Kurinna, Sabrina A. Stratton, Michelle C. Barton, Klaus H. Kaestner
PLoS Genet. 2012 Jun; 8(6): e1002770. Published online 2012 Jun 21. doi: 10.1371/journal.pgen.1002770
PMCID:
PMC3380847
AbstractArticlePDF–1.0M
18.
The Steroid and Xenobiotic Receptor Negatively Regulates B-1 Cell Development in the Fetal Liver
Stephanie C. Casey, Bruce Blumberg
Mol Endocrinol. 2012 Jun; 26(6): 916–925. Published online 2012 Apr 11. doi: 10.1210/me.2011-1303
PMCID:
PMC3355537
AbstractArticle
19.
Lentiviral Transgenic MicroRNA-Based shRNA Suppressed Mouse Cytochromosome P450 3A (CYP3A) Expression in a Dose-Dependent and Inheritable Manner
Yong Wang, Hai-Hong Hu, Hao Pang, Xiao-Yang Zhou, Lu-Shan Yu, Lu-Lu Wang, Cang'e Liu, Ke-Nan Guo, Cong Zhao, Qin Liu, Ben-Hua Zeng, Huan Tang, Hai-Tao Shang, Su Zeng, Hong Wei
PLoS One. 2012; 7(1): e30560. Published online 2012 Jan 24. doi: 10.1371/journal.pone.0030560
PMCID:
PMC3265487
AbstractArticlePDF–1012K
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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