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Items: 1 to 20 of 33

1.
A role for protease activated receptor type 3 (PAR3) in nociception demonstrated through development of a novel peptide agonist
Juliet Mwirigi, Moeno Kume, Shayne N Hassler, Ayesha Ahmad, Pradipta R Ray, Changyu Jiang, Alexander Chamessian, Nakleh Mseeh, Breya P Ludwig, Benjamin D. Rivera, Marvin T Nieman, Thomas Van de Ven, Ru-Rong Ji, Gregory Dussor, Scott Boitano, Josef Vagner, Theodore J Price
J Pain. Author manuscript; available in PMC 2022 Jun 1.
Published in final edited form as: J Pain. 2021 Jun; 22(6): 692–706. Published online 2021 Jan 9. doi: 10.1016/j.jpain.2020.12.006
PMCID:
PMC8197731
AbstractArticlePDF–2.3M
2.
The endothelial protein C receptor plays an essential role in the maintenance of pregnancy
Michelle M. Castillo, Qiuhui Yang, Abril Solis Sigala, Dosia T. McKinney, Min Zhan, Kristen L. Chen, Jason A. Jarzembowski, Rashmi Sood
Sci Adv. 2020 Nov; 6(45): eabb6196. Published online 2020 Nov 6. doi: 10.1126/sciadv.abb6196
PMCID:
PMC7673707
AbstractArticlePDF–1.6M
3.
Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal
Thomas W. Gould, Bertha Dominguez, Fred de Winter, Gene W. Yeo, Patrick Liu, Balaji Sundararaman, Thomas Stark, Anthony Vu, Jay L. Degen, Weichun Lin, Kuo-Fen Lee
PLoS Genet. 2019 Mar; 15(3): e1007948. Published online 2019 Mar 14. doi: 10.1371/journal.pgen.1007948
PMCID:
PMC6417855
AbstractArticlePDF–4.1M
4.
Activated protein C reverses epigenetically sustained p66Shc expression in plaque-associated macrophages in diabetes
Khurrum Shahzad, Ihsan Gadi, Sumra Nazir, Moh’d Mohanad Al-Dabet, Shrey Kohli, Fabian Bock, Lukas Breitenstein, Satish Ranjan, Tina Fuchs, Zuhir Halloul, Peter. P. Nawroth, Pier Giuseppe Pelicci, Ruediger C. Braun-Dullaeus, Eric Camerer, Charles T. Esmon, Berend Isermann
Commun Biol. 2018; 1: 104. Published online 2018 Aug 6. doi: 10.1038/s42003-018-0108-5
PMCID:
PMC6123684
AbstractArticlePDF–4.1M
5.
Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition
Sumra Nazir, Ihsan Gadi, Moh’d Mohanad Al-Dabet, Ahmed Elwakiel, Shrey Kohli, Sanchita Ghosh, Jayakumar Manoharan, Satish Ranjan, Fabian Bock, Ruediger C. Braun-Dullaeus, Charles T. Esmon, Tobias B. Huber, Eric Camerer, Chris Dockendorff, John H. Griffin, Berend Isermann, Khurrum Shahzad
Blood. 2017 Dec 14; 130(24): 2664–2677. Prepublished online 2017 Sep 7. doi: 10.1182/blood-2017-05-782102
PMCID:
PMC5731086
AbstractArticle
6.
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells
Satish Ranjan, Alexander Goihl, Shrey Kohli, Ihsan Gadi, Mandy Pierau, Khurrum Shahzad, Dheerendra Gupta, Fabian Bock, Hongjie Wang, Haroon Shaikh, Thilo Kähne, Dirk Reinhold, Ute Bank, Ana C. Zenclussen, Jana Niemz, Tina M. Schnöder, Monika Brunner-Weinzierl, Thomas Fischer, Thomas Kalinski, Burkhart Schraven, Thomas Luft, Jochen Huehn, Michael Naumann, Florian H. Heidel, Berend Isermann
Nat Commun. 2017; 8: 311. Published online 2017 Aug 21. doi: 10.1038/s41467-017-00169-4
PMCID:
PMC5566392
AbstractArticlePDF–2.2M
7.
Altered methylation of specific DNA loci in the liver of Bhmt-null mice results in repression of Iqgap2 and F2rl2 and is associated with development of preneoplastic foci
Daniel S. Lupu, Luz D. Orozco, Ying Wang, John M. Cullen, Matteo Pellegrini, Steven H. Zeisel
FASEB J. 2017 May; 31(5): 2090–2103. Published online 2017 Feb 8. doi: 10.1096/fj.201601169R
PMCID:
PMC5388550
AbstractArticle
8.
PDK1 is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division
Teruki Dainichi, Matthew S. Hayden, Sung-Gyoo Park, Hyunju Oh, John J. Seeley, Yenkel Grinberg-Bleyer, Kristen M. Beck, Yoshiki Miyachi, Kenji Kabashima, Takashi Hashimoto, Sankar Ghosh
Cell Rep. Author manuscript; available in PMC 2016 Jun 15.
Published in final edited form as: Cell Rep. 2016 May 24; 15(8): 1615–1623. Published online 2016 May 12. doi: 10.1016/j.celrep.2016.04.051
PMCID:
PMC4909264
AbstractArticlePDF–1.9M
9.
Thrombin stimulates insulin secretion via protease-activated receptor-3
Sonja Hänzelmann, Jinling Wang, Emre Güney, Yunzhao Tang, Enming Zhang, Annika S Axelsson, Hannah Nenonen, Albert S Salehi, Claes B Wollheim, Eva Zetterberg, Erik Berntorp, Ivan G Costa, Robert Castelo, Anders H Rosengren
Islets. 2015; 7(4): e1118195. Published online 2016 Jan 8. doi: 10.1080/19382014.2015.1118195
PMCID:
PMC4878264
AbstractArticlePDF–710K
10.
A balance between TFPI and thrombin-mediated platelet activation is required for murine embryonic development
Paul E. R. Ellery, Susan A. Maroney, Brian C. Cooley, James P. Luyendyk, Mark Zogg, Hartmut Weiler, Alan E. Mast
Blood. 2015 Jun 25; 125(26): 4078–4084. Prepublished online 2015 May 7. doi: 10.1182/blood-2015-03-633958
PMCID:
PMC4481595
AbstractArticle
11.
Slit/Robo Signaling Modulates the Proliferation of Central Nervous System Progenitors
Víctor Borrell, Adrián Cárdenas, Gabriele Ciceri, Joan Galcerán, Nuria Flames, Ramón Pla, Sandrina Nóbrega-Pereira, Cristina García-Frigola, Sandra Peregrín, Zhen Zhao, Le Ma, Marc Tessier-Lavigne, Oscar Marín
Neuron. Author manuscript; available in PMC 2015 May 26.
Published in final edited form as: Neuron. 2012 Oct 18; 76(2): 338–352. Published online 2012 Oct 17. doi: 10.1016/j.neuron.2012.08.003
PMCID:
PMC4443924
AbstractArticlePDF–3.1M
12.
EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice
Hai Po H. Liang, Edward J. Kerschen, Irene Hernandez, Sreemanti Basu, Mark Zogg, Fady Botros, Shuang Jia, Martin J. Hessner, John H. Griffin, Wolfram Ruf, Hartmut Weiler
Blood. 2015 Apr 30; 125(18): 2845–2854. Prepublished online 2015 Mar 2. doi: 10.1182/blood-2014-11-610717
Correction in:
Blood. 2018 May 31; 131(22): 2508.
PMCID:
PMC4424632
AbstractArticle
13.
Protease Activated Receptor-1 mediates cytotoxicity during ischemia using in vivo and in vitro models
Padmesh S Rajput, Patrick D Lyden, Bo Chen, Jessica A Lamb, Benedict Pereira, Alexander Lamb, Lifu Zhao, I-Farn Lei, Jilin Bai
Neuroscience. Author manuscript; available in PMC 2016 Mar 28.
Published in final edited form as: Neuroscience. 2014 Dec 5; 281: 229–240. Published online 2014 Sep 28. doi: 10.1016/j.neuroscience.2014.09.038
PMCID:
PMC4377119
AbstractArticlePDF–2.3M
14.
Redundancy and interaction of thrombin- and collagen-mediated platelet activation in tail bleeding and carotid thrombosis in mice
Yamini S. Bynagari-Settipalli, Ivo Cornelissen, Daniel Palmer, Daniel Duong, Cherry Concengco, Jerry Ware, Shaun R. Coughlin
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2015 Dec 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Dec; 34(12): 2563–2569. Published online 2014 Oct 2. doi: 10.1161/ATVBAHA.114.304244
PMCID:
PMC4239193
AbstractArticlePDF–1.3M
15.
Kallikrein 6 Signals through PAR1 and PAR2 to Promote Neuron Injury and Exacerbate Glutamate Neurotoxicity
Hyesook Yoon, Maja Radulovic, Jianmin Wu, Sachiko I. Blaber, Michael Blaber, Michael G. Fehlings, Isobel A. Scarisbrick
J Neurochem. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: J Neurochem. 2013 Oct; 127(2): 283–298. Published online 2013 May 27. doi: 10.1111/jnc.12293
PMCID:
PMC4097186
AbstractArticlePDF–1.5M
16.
Platelet Specific Promoters Are Insufficient to Express Protease Activated Receptor 1 (PAR1) Transgene in Mouse Platelets
Amal Arachiche, María de la Fuente, Marvin T. Nieman
PLoS One. 2014; 9(5): e97724. Published online 2014 May 15. doi: 10.1371/journal.pone.0097724
PMCID:
PMC4022678
AbstractArticlePDF–819K
17.
Heparin rescues factor V Leiden–associated placental failure independent of anticoagulation in a murine high-risk pregnancy model
Jianzhong An, Magarya S. Waitara, Michelle Bordas, Vidhyalakshmi Arumugam, Raymond G. Hoffmann, Brian G. Petrich, Uma Sinha, Paula E. North, Rashmi Sood
Blood. 2013 Mar 14; 121(11): 2127–2134. Prepublished online 2013 Jan 16. doi: 10.1182/blood-2012-08-448209
PMCID:
PMC3952382
AbstractArticle
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Calcium Mobilization And Protein Kinase C Activation Downstream Of Protease Activated Receptor 4 (PAR4) Is Negatively Regulated By PAR3 In Mouse Platelets
Amal Arachiche, María de la Fuente, Marvin T. Nieman
PLoS One. 2013; 8(2): e55740. Published online 2013 Feb 6. doi: 10.1371/journal.pone.0055740
Correction in:
PLoS One. 2013; 8(12): 10.1371/annotation/0956857d-ecf5-4fb7-a834-131915a38a6a.
PMCID:
PMC3566007
AbstractArticlePDF–1017K
20.
Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes
Thati Madhusudhan, Hongjie Wang, Beate K. Straub, Elisabeth Gröne, Qianxing Zhou, Khurrum Shahzad, Sandra Müller-Krebs, Vedat Schwenger, Bruce Gerlitz, Brian W. Grinnell, John H. Griffin, Jochen Reiser, Hermann-Josef Gröne, Charles T. Esmon, Peter P. Nawroth, Berend Isermann
Blood. 2012 Jan 19; 119(3): 874–883. Prepublished online 2011 Nov 23. doi: 10.1182/blood-2011-07-365973
PMCID:
PMC3398751
AbstractArticle

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