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Items: 1 to 20 of 35

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice
Jennifer K. Truong, Jianing Li, Qin Li, Kimberly Pachura, Anuradha Rao, Sanjeev Gumber, Claudia Daniela Fuchs, Andrew P. Feranchak, Saul J. Karpen, Michael Trauner, Paul A. Dawson
JCI Insight. 2023 Mar 22; 8(6): e149360. Published online 2023 Mar 22. doi: 10.1172/jci.insight.149360
PMCID:
PMC10070106
AbstractArticlePDF–3.1M
3.
Loss of apical sodium bile acid transporter alters bile acid circulation and reduces biliary damage in cholangitis
Vik Meadows, Corinn Marakovits, Burcin Ekser, Debjyoti Kundu, Tianhao Zhou, Konstantina Kyritsi, Linh Pham, Lixian Chen, Lindsey Kennedy, Ludovica Ceci, Nan Wu, Guido Carpino, Wenjun Zhang, Abdulkadir Isidan, Alison Meyer, Travis Owen, Eugenio Gaudio, Paolo Onori, Gianfranco Alpini, Heather Francis
Am J Physiol Gastrointest Liver Physiol. 2023 Jan 1; 324(1): G60–G77. Published online 2022 Nov 21. doi: 10.1152/ajpgi.00112.2022
PMCID:
PMC9799145
AbstractArticle
4.
CAR directs T cell adaptation to bile acids in the small intestine
Mei Lan Chen, Xiangsheng Huang, Hongtao Wang, Courtney Hegner, Yujin Liu, Jinsai Shang, Amber Eliason, Huitian Diao, HaJeung Park, Blake Frey, Guohui Wang, Sarah A. Mosure, Laura A. Solt, Douglas J. Kojetin, Alex Rodriguez-Palacios, Deborah A. Schady, Casey T. Weaver, Matthew E. Pipkin, David D. Moore, Mark S. Sundrud
Nature. Author manuscript; available in PMC 2022 Feb 22.
Published in final edited form as: Nature. 2021 May; 593(7857): 147–151. Published online 2021 Apr 7. doi: 10.1038/s41586-021-03421-6
PMCID:
PMC8862117
AbstractArticlePDF–4.8M
5.
Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions
Alex Zaufel, Sandra M.W. van de Wiel, Lu Yin, Günter Fauler, Daphne Chien, Xinzhong Dong, John F. Gilmer, Jennifer K. Truong, Paul A. Dawson, Stan F. J. van de Graaf, Peter Fickert, Tarek Moustafa
Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2021 Aug 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2021 Aug 1; 1867(8): 166153. Published online 2021 Apr 22. doi: 10.1016/j.bbadis.2021.166153
PMCID:
PMC8177068
AbstractArticlePDF–1.5M
6.
Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration
Brian J. Pepe-Mooney, Michael T. Dill, Anna Alemany, Jose Ordovas-Montanes, Yuki Matsushita, Anuradha Rao, Anushna Sen, Makoto Miyazaki, Sayeepriyadarshini Anakk, Paul A. Dawson, Noriaki Ono, Alex K. Shalek, Alexander van Oudenaarden, Fernando D. Camargo
Cell Stem Cell. Author manuscript; available in PMC 2020 Jul 3.
Published in final edited form as: Cell Stem Cell. 2019 Jul 3; 25(1): 23–38.e8. Published online 2019 May 9. doi: 10.1016/j.stem.2019.04.004
PMCID:
PMC6814390
AbstractArticlePDF–5.7M
7.
Genetic determinants of gut microbiota composition and bile acid profiles in mice
Julia H. Kemis, Vanessa Linke, Kelsey L. Barrett, Frederick J. Boehm, Lindsay L. Traeger, Mark P. Keller, Mary E. Rabaglia, Kathryn L. Schueler, Donald S. Stapleton, Daniel M. Gatti, Gary A. Churchill, Daniel Amador-Noguez, Jason D. Russell, Brian S. Yandell, Karl W. Broman, Joshua J. Coon, Alan D. Attie, Federico E. Rey
PLoS Genet. 2019 Aug; 15(8): e1008073. Published online 2019 Aug 29. doi: 10.1371/journal.pgen.1008073
PMCID:
PMC6715156
AbstractArticlePDF–2.1M
8.
The xenobiotic transporter Mdr1 enforces T cell homeostasis in the presence of intestinal bile acids
Wei Cao, Hisako Kayama, Mei Lan Chen, Amber Delmas, Amy Sun, Sang Yong Kim, Erumbi S. Rangarajan, Kelly McKevitt, Amanda P. Beck, Cody B. Jackson, Gogce Crynen, Angelos Oikonomopoulos, Precious N. Lacey, Gustavo J. Martinez, Tina Izard, Robin G. Lorenz, Alex Rodriguez-Palacios, Fabio Cominelli, Maria T. Abreu, Daniel W. Hommes, Sergei B. Koralov, Kiyoshi Takeda, Mark S. Sundrud
Immunity. Author manuscript; available in PMC 2018 Dec 19.
Published in final edited form as: Immunity. 2017 Dec 19; 47(6): 1182–1196.e10. doi: 10.1016/j.immuni.2017.11.012
Correction in:
Immunity. 2020 Mar 17; 52(3): 571.
PMCID:
PMC5741099
AbstractArticlePDF–1.6M
9.
Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4
Carolien Out, Jay V. Patankar, Marcela Doktorova, Marije Boesjes, Trijnie Bos, Sanna de Boer, Rick Havinga, Henk Wolters, Renze Boverhof, Theo H. van Dijk, Anna Smoczek, André Bleich, Vinay Sachdev, Dagmar Kratky, Folkert Kuipers, Henkjan J. Verkade, Albert K. Groen
J Hepatol. Author manuscript; available in PMC 2017 Feb 6.
Published in final edited form as: J Hepatol. 2015 Sep; 63(3): 697–704. Published online 2015 May 27. doi: 10.1016/j.jhep.2015.04.030
PMCID:
PMC5293168
AbstractArticlePDF–1.0M
10.
Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders
Jessica M. Ferrell, Shannon Boehme, Feng Li, John Y. L. Chiang
J Lipid Res. 2016 Jul; 57(7): 1144–1154. doi: 10.1194/jlr.M064709
PMCID:
PMC4918844
AbstractArticlePDF–1.3M
11.
Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids
Jean-Pierre Raufman, Paul A. Dawson, Anuradha Rao, Cinthia B. Drachenberg, Jonathon Heath, Aaron C. Shang, Shien Hu, Min Zhan, James E. Polli, Kunrong Cheng
Carcinogenesis. 2015 Oct; 36(10): 1193–1200. Published online 2015 Jul 25. doi: 10.1093/carcin/bgv107
PMCID:
PMC4612337
AbstractArticlePDF–3.6M
12.
Maternal bile acid transporter deficiency promotes neonatal demise
Yuanyuan Zhang, Fei Li, Yao Wang, Aaron Pitre, Zhong-ze Fang, Matthew W. Frank, Christopher Calabrese, Kristopher W. Krausz, Geoffrey Neale, Sharon Frase, Peter Vogel, Charles O. Rock, Frank J. Gonzalez, John D. Schuetz
Nat Commun. 2015; 6: 8186. Published online 2015 Sep 29. doi: 10.1038/ncomms9186
PMCID:
PMC4598356
AbstractArticlePDF–1.5M
13.
Mapping the H+ (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation
Maria Merkulova, Teodor G. Păunescu, Anie Azroyan, Vladimir Marshansky, Sylvie Breton, Dennis Brown
Sci Rep. 2015; 5: 14827. Published online 2015 Oct 7. doi: 10.1038/srep14827
PMCID:
PMC4595830
AbstractArticlePDF–1.5M
14.
GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development
Emily M. Walker, Cayla A. Thompson, Michele A. Battle
Dev Biol. Author manuscript; available in PMC 2015 Aug 15.
Published in final edited form as: Dev Biol. 2014 Aug 15; 392(2): 283–294. Published online 2014 Jun 12. doi: 10.1016/j.ydbio.2014.05.017
PMCID:
PMC4149467
AbstractArticlePDF–2.0M
15.
Bile Acid Flux Is Necessary for Normal Liver Regeneration
Willscott E. Naugler
PLoS One. 2014; 9(5): e97426. Published online 2014 May 19. doi: 10.1371/journal.pone.0097426
PMCID:
PMC4026228
AbstractArticlePDF–4.7M
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels
Laurent Vergnes, Jessica M. Lee, Robert G. Chin, Johan Auwerx, Karen Reue
Cell Metab. Author manuscript; available in PMC 2014 Jun 4.
Published in final edited form as: Cell Metab. 2013 Jun 4; 17(6): 916–928. doi: 10.1016/j.cmet.2013.04.007
PMCID:
PMC3956443
AbstractArticlePDF–3.9M
18.
Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE−/− mice
Tian Lan, Jamie Haywood, Paul A. Dawson
Atherosclerosis. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: Atherosclerosis. 2013 Aug; 229(2): 374–380. Published online 2013 May 28. doi: 10.1016/j.atherosclerosis.2013.05.017
PMCID:
PMC3724224
AbstractArticlePDF–1.4M
19.
Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice
Inik Chang, Alexa N. Bramall, Amy Greenstein Baynash, Amir Rattner, Dinesh Rakheja, Martin Post, Stephen Joza, Colin McKerlie, Duncan J. Stewart, Roderick R. McInnes, Masashi Yanagisawa
J Clin Invest. 2013 Jun 3; 123(6): 2643–2653. Published online 2013 May 8. doi: 10.1172/JCI66735
PMCID:
PMC3668837
AbstractArticlePDF–2.1M
20.
Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism
Tian Lan, Anuradha Rao, Jamie Haywood, Nancy D. Kock, Paul A. Dawson
J Hepatol. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: J Hepatol. 2012 Aug; 57(2): 359–365. Published online 2012 Apr 25. doi: 10.1016/j.jhep.2012.03.025
PMCID:
PMC3575595
AbstractArticlePDF–1.7M

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