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Select item 114845081.

KDM6A/UTX promotes spermatogenic gene expression across generations and is not required for male fertility

Benjamin W Walters, Shannon R Rainsford, Rachel A Heuer, Nicolas Dias, Xiaofang Huang, Dirk de Rooij, Bluma J Lesch

Biol Reprod. 2024 Feb; 110(2): 391–407. Published online 2023 Oct 20. doi: 10.1093/biolre/ioad141

PMCID:: PMC11484508

Abstract Article PDF–2.5M

Select item 113881822.

Control of epigenomic landscape and development of fetal male germ cells through L-serine metabolism

Yohei Hayashi, Jintaro Kaneko, Yumi Ito-Matsuoka, Asuka Takehara, Mayuka Funakoshi, So Maezawa, Kenjiro Shirane, Shigeki Furuya, Yasuhisa Matsui

iScience. 2024 Sep 20; 27(9): 110702. Published online 2024 Aug 9. doi: 10.1016/j.isci.2024.110702

PMCID:: PMC11388182

Abstract Article PDF–6.4M

Select item 113815323.

Protein phosphatase 4 maintains the survival of primordial follicles by regulating autophagy in oocytes

Ming-Zhe Dong, Ying-Chun Ouyang, Shi-Cai Gao, Lin-Jian Gu, Jia-Ni Guo, Si-Min Sun, Zhen-Bo Wang, Qing-Yuan Sun

Cell Death Dis. 2024 Sep; 15(9): 658. Published online 2024 Sep 8. doi: 10.1038/s41419-024-07051-4

PMCID:: PMC11381532

Abstract Article PDF–6.1M

Select item 113461814.

Casein kinase 1α mediates estradiol secretion via CYP19A1 expression in mouse ovarian granulosa cells

Xuan Luo, Di Zhang, Jiaming Zheng, Hui Liu, Longjie Sun, Hongzhou Guo, Lei Wang, Sheng Cui

BMC Biol. 2024; 22: 176. Published online 2024 Aug 26. doi: 10.1186/s12915-024-01957-3

PMCID:: PMC11346181

Abstract Article PDF–2.9M

Select item 112511675.

MCM8 interacts with DDX5 to promote R-loop resolution

Canxin Wen, Lili Cao, Shuhan Wang, Weiwei Xu, Yongze Yu, Simin Zhao, Fan Yang, Zi-Jiang Chen, Shidou Zhao, Yajuan Yang, Yingying Qin

EMBO J. 2024 Jul; 43(14): 3044–3071. Published online 2024 Jun 10. doi: 10.1038/s44318-024-00134-0

PMCID:: PMC11251167

Abstract Article PDF–8.7M

Select item 110729796.

Dissecting the initiation of female meiosis in the mouse at single-cell resolution

Wei Ge, Jun-Jie Wang, Rui-Qian Zhang, Shao-Jing Tan, Fa-Li Zhang, Wen-Xiang Liu, Lan Li, Xiao-Feng Sun, Shun-Feng Cheng, Paul W. Dyce, Massimo De Felici, Wei Shen

Cell Mol Life Sci. 2021 Jan; 78(2): 695–713. Published online 2020 May 4. doi: 10.1007/s00018-020-03533-8

PMCID:: PMC11072979

Abstract Article PDF–16M

Select item 109594157.

FOXL2 interaction with different binding partners regulates the dynamics of ovarian development

Roberta Migale, Michelle Neumann, Richard Mitter, Mahmoud-Reza Rafiee, Sophie Wood, Jessica Olsen, Robin Lovell-Badge

Sci Adv. 2024 Mar 22; 10(12): eadl0788. Published online 2024 Mar 22. doi: 10.1126/sciadv.adl0788

PMCID:: PMC10959415

Abstract Article PDF–4.4M

Select item 109098938.

MAX controls meiotic entry in sexually undifferentiated germ cells

Ayumu Suzuki, Kousuke Uranishi, Masazumi Nishimoto, Yosuke Mizuno, Seiya Mizuno, Satoru Takahashi, Robert N. Eisenman, Akihiko Okuda

Sci Rep. 2024; 14: 5236. Published online 2024 Mar 4. doi: 10.1038/s41598-024-55506-7

PMCID:: PMC10909893

Abstract Article PDF–7.0M

Select item 108540489.

Loss of Calponin 2 causes premature ovarian insufficiency in mice

Tzu-Bou Hsieh, Jian-Ping Jin

J Ovarian Res. 2024; 17: 37. Published online 2024 Feb 9. doi: 10.1186/s13048-024-01346-y

PMCID:: PMC10854048

Abstract Article PDF–4.8M

Select item 1075358710.

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis

Sirine Souali-Crespo, Diana Condrea, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Erwan Grandgirard, Violaine Alunni, Marie Cerciat, Matthieu Jung, Chloé Mayere, Serge Nef, Manuel Mark, Frédéric Chalmel, Norbert B. Ghyselinck

Development. 2023 Dec 15; 150(24): dev201710. Published online 2023 Dec 11. doi: 10.1242/dev.201710

PMCID:: PMC10753587

Abstract Article

Select item 1065410111.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 1062644312.

Nutritional and metabolic control of germ cell fate through O‐GlcNAc regulation

Yohei Hayashi, Yukiko Tando, Yumi Ito‐Matsuoka, Kaho Ikuta, Asuka Takehara, Katsutaro Morino, Hiroshi Maegawa, Yasuhisa Matsui

EMBO Rep. 2023 Nov; 24(11): e56845. Published online 2023 Oct 16. doi: 10.15252/embr.202356845

PMCID:: PMC10626443

Abstract Article PDF–2.9M

Select item 1057727813.

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice

Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II

Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077

PMCID:: PMC10577278

Abstract Article PDF–1.9M

Select item 1052063714.

NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition

Tie‐Gang Meng, Jia‐Ni Guo, Liu Zhu, Yike Yin, Feng Wang, Zhi‐Ming Han, Lei Lei, Xue‐Shan Ma, Yue Xue, Wei Yue, Xiao‐Qing Nie, Zheng‐Hui Zhao, Hong‐Yong Zhang, Si‐Min Sun, Ying‐Chun Ouyang, Yi Hou, Heide Schatten, Zhenyu Ju, Xiang‐Hong Ou, Zhen‐Bo Wang, Catherine C. L. Wong, Zhonghan Li, Qing‐Yuan Sun

Adv Sci (Weinh) 2023 Sep; 10(27): 2301940. Published online 2023 Jul 26. doi: 10.1002/advs.202301940

PMCID:: PMC10520637

Abstract Article PDF–6.6M

Select item 1050573215.

Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure

Penny A. F. Whiley, Michael C. M. Luu, Liza O’Donnell, David J. Handelsman, Kate L. Loveland

Front Endocrinol (Lausanne) 2023; 14: 1234712. Published online 2023 Sep 1. doi: 10.3389/fendo.2023.1234712

PMCID:: PMC10505732

Abstract Article PDF–9.9M

Select item 1042615416.

FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells

Weiwei Xu, Yajuan Yang, Yongze Yu, Canxin Wen, Simin Zhao, Lili Cao, Shidou Zhao, Yingying Qin, Zi-Jiang Chen

BMC Biol. 2023; 21: 174. Published online 2023 Aug 15. doi: 10.1186/s12915-023-01676-1

PMCID:: PMC10426154

Abstract Article PDF–6.6M

Select item 1041512817.

ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development

Adda-Lee Graham-Paquin, Deepak Saini, Jacinthe Sirois, Ishtiaque Hossain, Megan S Katz, Qinwei Kim-Wee Zhuang, Sin Young Kwon, Yojiro Yamanaka, Guillaume Bourque, Maxime Bouchard, William A Pastor

Nucleic Acids Res. 2023 Aug 11; 51(14): 7314–7329. Published online 2023 Jul 3. doi: 10.1093/nar/gkad540

PMCID:: PMC10415128

Abstract Article PDF–2.6M

Select item 1039049218.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1025966019.

DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement

Aushaq B. Malla, Shannon R. Rainsford, Zachary D. Smith, Bluma J. Lesch

Development. 2023 May 1; 150(9): dev201497. Published online 2023 May 12. doi: 10.1242/dev.201497

PMCID:: PMC10259660

Abstract Article

Select item 1016458220.

SPIDR is required for homologous recombination during mammalian meiosis

Tao Huang, Xinyue Wu, Shiyu Wang, Ziyou Bao, Yanling Wan, Ziqi Wang, Mengjing Li, Xiaochen Yu, Yue Lv, Zhaojian Liu, Xiangfeng Chen, Wai-Yee Chan, Fei Gao, Gang Lu, Zi-Jiang Chen, Hongbin Liu

Nucleic Acids Res. 2023 May 8; 51(8): 3855–3868. Published online 2023 Mar 20. doi: 10.1093/nar/gkad154