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Select item 112177831.

Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner

Davy Vanhoutte, Tobias G. Schips, Rachel A. Minerath, Jiuzhou Huo, Naga Swathi Sree Kavuri, Vikram Prasad, Suh-Chin Lin, Michael J. Bround, Michelle A. Sargent, Christopher M. Adams, Jeffery D. Molkentin

Cell Rep. Author manuscript; available in PMC 2024 Jul 2.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114149. Published online 2024 Apr 26. doi: 10.1016/j.celrep.2024.114149

PMCID:: PMC11217783

Abstract Article PDF–3.2M

Select item 106559182.

The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFβ signaling pathways to drive tongue organogenesis

Jingyue Xu, Han Liu, Yu Lan, Rulang Jiang

Development. 2022 Nov 1; 149(21): dev200667. Published online 2022 Oct 28. doi: 10.1242/dev.200667

PMCID:: PMC10655918

Abstract Article

Select item 106541013.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 101191214.

Topologically associating domain boundaries are required for normal genome function

Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li, Ana Alcaina Caro, Yoko Fukuda-Yuzawa, Guy Kelman, Adyam Akeza, Matthew J. Blow, Quan Pham, Anne N. Harrington, Janeth Godoy, Eman M. Meky, Kianna von Maydell, Riana D. Hunter, Jennifer A. Akiyama, Catherine S. Novak, Ingrid Plajzer-Frick, Veena Afzal, Stella Tran, Javier Lopez-Rios, Michael E. Talkowski, K. C. Kent Lloyd, Bing Ren, Diane E. Dickel, Axel Visel, Len A. Pennacchio

Commun Biol. 2023; 6: 435. Published online 2023 Apr 20. doi: 10.1038/s42003-023-04819-w

PMCID:: PMC10119121

Abstract Article PDF–3.2M

Select item 99515945.

Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation

Georgia Zarkada, Joel P. Howard, Xue Xiao, Hyojin Park, Mathilde Bizou, Severine Leclerc, Steffen E. Künzel, Blanche Boisseau, Jinyu Li, Gael Cagnone, Jean Sebastien Joyal, Gregor Andelfinger, Anne Eichmann, Alexandre Dubrac

Dev Cell. Author manuscript; available in PMC 2023 Feb 24.

Published in final edited form as: Dev Cell. 2021 Aug 9; 56(15): 2237–2251.e6. Published online 2021 Jul 16. doi: 10.1016/j.devcel.2021.06.021

PMCID:: PMC9951594

Abstract Article PDF–3.9M

Select item 98700896.

ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis

Sudhir Kumar, Xueping Fan, Hila Milo Rasouly, Richa Sharma, David J. Salant, Weining Lu

JCI Insight. 2023 Jan 10; 8(1): e158418. Published online 2023 Jan 10. doi: 10.1172/jci.insight.158418

PMCID:: PMC9870089

Abstract Article PDF–8.1M

Select item 97713657.

TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

Jifan Feng, Xia Han, Yuan Yuan, Courtney Kyeong Cho, Eva Janečková, Tingwei Guo, Siddhika Pareek, Md Shaifur Rahman, Banghong Zheng, Jing Bi, Junjun Jing, Mingyi Zhang, Jian Xu, Thach-Vu Ho, Yang Chai

eLife. 2022; 11: e80405. Published online 2022 Dec 21. doi: 10.7554/eLife.80405

PMCID:: PMC9771365

Abstract Article PDF–17M

Select item 97416288.

Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas

Haifeng Zhang, Busu Li, Qunhua Huang, Francesc López-Giráldez, Yoshiaki Tanaka, Qun Lin, Sameet Mehta, Guilin Wang, Morven Graham, Xinran Liu, In-Hyun Park, Anne Eichmann, Wang Min, Jenny Huanjiao Zhou

Nat Commun. 2022; 13: 7637. Published online 2022 Dec 10. doi: 10.1038/s41467-022-35262-w

PMCID:: PMC9741628

Abstract Article PDF–16M

Select item 97137169.

Maternal immune activation leads to defective brain–blood vessels and intracerebral hemorrhages in male offspring

Marco Rasile, Eliana Lauranzano, Elisa Faggiani, Margherita M Ravanelli, Federico S Colombo, Filippo Mirabella, Irene Corradini, Maria L Malosio, Antonella Borreca, Elisa Focchi, Davide Pozzi, Toni Giorgino, Isabella Barajon, Michela Matteoli

EMBO J. 2022 Dec; 41(23): e111192. Published online 2022 Oct 31. doi: 10.15252/embj.2022111192

Correction in:: EMBO J. 2023 May; 42(10): e113890.

PMCID:: PMC9713716

Abstract Article PDF–3.2M

Select item 970123710.

Creb5 coordinates synovial joint formation with the genesis of articular cartilage

Cheng-Hai Zhang, Yao Gao, Han-Hwa Hung, Zhu Zhuo, Alan J. Grodzinsky, Andrew B. Lassar

Nat Commun. 2022; 13: 7295. Published online 2022 Nov 26. doi: 10.1038/s41467-022-35010-0

PMCID:: PMC9701237

Abstract Article PDF–10M

Select item 962426211.

Endothelial loss of ETS1 impairs coronary vascular development and leads to ventricular non-compaction

Lu Wang, Lizhu Lin, Hui Qi, Ju Chen, Paul Grossfeld

Circ Res. Author manuscript; available in PMC 2023 Aug 19.

Published in final edited form as: Circ Res. 2022 Aug 19; 131(5): 371–387. Published online 2022 Jul 27. doi: 10.1161/CIRCRESAHA.121.319955

PMCID:: PMC9624262

Abstract Article PDF–4.5M

Select item 960672212.

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development

Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener

Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.

Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002

PMCID:: PMC9606722

Abstract Article PDF–6.7M

Select item 943705913.

Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition

Anna Ruiz-Mitjana, Raúl Navaridas, Maria Vidal-Sabanés, Aida Perramon-Güell, Andree Yeramian, Isidre Felip, Núria Eritja, Joaquim Egea, Mario Encinas, Xavier Matias-Guiu, Xavier Dolcet

Sci Rep. 2022; 12: 14821. Published online 2022 Sep 1. doi: 10.1038/s41598-022-18976-1

PMCID:: PMC9437059

Abstract Article PDF–7.1M

Select item 932868014.

SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8⁺ T cell cytotoxic function

Xinwei Liu, Jing Hao, Peng Wei, Xiaohong Zhao, Qiuyan Lan, Lu Ni, Yongzhen Chen, Xue Bai, Ling Ni, Chen Dong

Sci Adv. 2022 Jul; 8(30): eabo4577. Published online 2022 Jul 27. doi: 10.1126/sciadv.abo4577

PMCID:: PMC9328680

Abstract Article PDF–3.4M

Select item 923958015.

Bcar1/p130Cas is essential for ventricular development and neural crest cell remodelling of the cardiac outflow tract

Marwa Mahmoud, Ian Evans, Laura Wisniewski, Yuen Tam, Claire Walsh, Simon Walker-Samuel, Paul Frankel, Peter Scambler, Ian Zachary

Cardiovasc Res. 2022 May; 118(8): 1993–2005. Published online 2021 Jul 16. doi: 10.1093/cvr/cvab242

PMCID:: PMC9239580

Abstract Article PDF–1.9M

Select item 923587516.

Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis

Sabrina Shameen Alam, Shruti Kumar, Marie-Claude Beauchamp, Eric Bareke, Alexia Boucher, Nadine Nzirorera, Yanchen Dong, Reinnier Padilla, Si Jing Zhang, Jacek Majewski, Loydie A. Jerome-Majewska

Dis Model Mech. 2022 Jun 1; 15(6): dmm049544. Published online 2022 Jun 23. doi: 10.1242/dmm.049544

PMCID:: PMC9235875

Abstract Article

Select item 910554417.

Loss of Smad4 in the Scleraxis Cell Lineage Results in Postnatal Joint Contracture

Saundra Schlesinger, Seongkyung Seo, Brian Pryce, Sara F. Tufa, Douglas R. Keene, Alice H. Huang, Ronen Schweitzer

Dev Biol. Author manuscript; available in PMC 2022 May 13.

Published in final edited form as: Dev Biol. 2021 Feb; 470: 108–120. Published online 2020 Nov 25. doi: 10.1016/j.ydbio.2020.11.006

PMCID:: PMC9105544

Abstract Article PDF–2.4M

Select item 906430518.

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development

Timothy J Mead, Daniel R Martin, Lauren W Wang, Stuart A Cain, Cagri Gulec, Elisabeth Cahill, Joseph Mauch, Dieter Reinhardt, Cecilia Lo, Clair Baldock, Suneel S Apte

eLife. 2022; 11: e71142. Published online 2022 May 3. doi: 10.7554/eLife.71142

PMCID:: PMC9064305

Abstract Article PDF–25M

Select item 902827219.

miR-152-3p Represses the Proliferation of the Thymic Epithelial Cells by Targeting Smad2

Ying Li, Xintong Wang, Qingru Wu, Fenfen Liu, Lin Yang, Bishuang Gong, Kaizhao Zhang, Yongjiang Ma, Yugu Li

Genes (Basel) 2022 Apr; 13(4): 576. Published online 2022 Mar 24. doi: 10.3390/genes13040576

PMCID:: PMC9028272

Abstract Article PDF–2.3M

Select item 898800820.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Abstract Article PDF–6.1M

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