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Select item 106764251.

Modulation of insulin secretion by RBFOX2-mediated alternative splicing

Nicole D. Moss, Kristen L. Wells, Alexandra Theis, Yong-Kyung Kim, Aliya F. Spigelman, Xiong Liu, Patrick E. MacDonald, Lori Sussel

Nat Commun. 2023; 14: 7732. Published online 2023 Nov 25. doi: 10.1038/s41467-023-43605-4

PMCID:: PMC10676425

Abstract Article PDF–4.7M

Select item 98671192.

Suppression of RBFox2 by Multiple MiRNAs in Pressure Overload-Induced Heart Failure

Mingyao Gu, Yuying Zhao, Hong Wang, Wanwen Cheng, Jie Liu, Kunfu Ouyang, Chaoliang Wei

Int J Mol Sci. 2023 Jan; 24(2): 1283. Published online 2023 Jan 9. doi: 10.3390/ijms24021283

PMCID:: PMC9867119

Abstract Article PDF–2.7M

Select item 97718203.

Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice

Helen A. B. Paterson, Sijia Yu, Natalia Artigas, Miguel A. Prado, Nejc Haberman, Yi-Fang Wang, Andrew M. Jobbins, Elena Pahita, Joao Mokochinski, Zoe Hall, Maryse Guerin, Joao A. Paulo, Soon Seng Ng, Francesc Villarroya, Sheikh Tamir Rashid, Wilfried Le Goff, Boris Lenhard, Inês Cebola, Daniel Finley, Steven P. Gygi, Christopher R. Sibley, Santiago Vernia

Nat Metab. 2022; 4(12): 1812–1829. Published online 2022 Dec 19. doi: 10.1038/s42255-022-00681-y

PMCID:: PMC9771820

Abstract Article PDF–9.9M

Select item 88818024.

RBFOX2 is required for establishing RNA regulatory networks essential for heart development

Sunil K Verma, Vaibhav Deshmukh, Kaitlyn Thatcher, KarryAnne K Belanger, Alexander M Rhyner, Shu Meng, Richard Joshua Holcomb, Michael Bressan, James F Martin, John P Cooke, Joshua D Wythe, Steven G Widen, Joy Lincoln, Muge N Kuyumcu-Martinez

Nucleic Acids Res. 2022 Feb 28; 50(4): 2270–2286. Published online 2022 Feb 7. doi: 10.1093/nar/gkac055

PMCID:: PMC8881802

Abstract Article PDF–16M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76650167.

The effect of Rbfox2 modulation on retinal transcriptome and visual function

Lei Gu, Riki Kawaguchi, Joseph Caprioli, Natik Piri

Sci Rep. 2020; 10: 19683. Published online 2020 Nov 12. doi: 10.1038/s41598-020-76879-5

PMCID:: PMC7665016

Abstract Article PDF–3.3M

Select item 75541998.

Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity

Bridget E. Begg, Marvin Jens, Peter Y. Wang, Christine M. Minor, Christopher B. Burge

Nat Struct Mol Biol. Author manuscript; available in PMC 2021 Feb 17.

Published in final edited form as: Nat Struct Mol Biol. 2020 Oct; 27(10): 901–912. Published online 2020 Aug 17. doi: 10.1038/s41594-020-0475-8

PMCID:: PMC7554199

Abstract Article PDF–4.5M

Select item 70988529.

Aberrant expression of a non-muscle RBFOX2 isoform triggers cardiac conduction defects in myotonic dystrophy

Chaitali Misra, Sushant Bangru, Feikai Lin, Kin Lam, Sara N. Koenig, Ellen R. Lubbers, Jamila Hedhli, Nathaniel P. Murphy, Darren J. Parker, Lawrence W. Dobrucki, Thomas A. Cooper, Emad Tajkhorshid, Peter J. Mohler, Auinash Kalsotra

Dev Cell. Author manuscript; available in PMC 2021 Mar 23.

Published in final edited form as: Dev Cell. 2020 Mar 23; 52(6): 748–763.e6. Published online 2020 Feb 27. doi: 10.1016/j.devcel.2020.01.037

PMCID:: PMC7098852

Abstract Article PDF–3.4M

Select item 699424710.

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

Samudyata, Paulo P. Amaral, Pär G. Engström, Samuel C. Robson, Michael L. Nielsen, Tony Kouzarides, Gonçalo Castelo-Branco

Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 129–138. Published online 2019 May 9. doi: 10.1016/j.yexcr.2019.05.006

PMCID:: PMC6994247

Abstract Article PDF–1.6M

Select item 695496711.

Genes of the cGMP-PKG-Ca²⁺ signaling pathway are alternatively spliced in cardiomyopathy: Role of RBFOX2

Xianxiu Wan, KarryAnne Belanger, Steven G Widen, Muge N Kuyumcu-Martinez, Nisha J Garg

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1; 1866(3): 165620. Published online 2019 Nov 25. doi: 10.1016/j.bbadis.2019.165620

PMCID:: PMC6954967

Abstract Article PDF–2.5M

Select item 670483212.

Ric-8a, a Guanine Nucleotide Exchange Factor for Heterotrimeric G Proteins, Regulates Bergmann Glia-Basement Membrane Adhesion during Cerebellar Foliation

Shang Ma, Hyo Jun Kwon, Zhen Huang

J Neurosci. 2012 Oct 24; 32(43): 14979–14993. doi: 10.1523/JNEUROSCI.1282-12.2012

PMCID:: PMC6704832

Abstract Article PDF–3.5M

Select item 666329513.

Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate

Dasan Mary Cibi, Masum M Mia, Shamini Guna Shekeran, Lim Sze Yun, Reddemma Sandireddy, Priyanka Gupta, Monalisa Hota, Lei Sun, Sujoy Ghosh, Manvendra K Singh

eLife. 2019; 8: e45418. Published online 2019 Jun 26. doi: 10.7554/eLife.45418

PMCID:: PMC6663295

Abstract Article PDF–8.2M

Select item 660230014.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 644257515.

RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure

Jing Hu, Chen Gao, Chaoliang Wei, Yuanchao Xue, Changwei Shao, Yajing Hao, Lan-Tao Gou, Yu Zhou, Jianlin Zhang, Shuxun Ren, Ju Chen, Yibin Wang, Xiang-Dong Fu

Proc Natl Acad Sci U S A. 2019 Mar 26; 116(13): 6172–6180. Published online 2019 Mar 13. doi: 10.1073/pnas.1822176116

PMCID:: PMC6442575

Abstract Article PDF–1.7M

Select item 610571716.

Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis

Marissa A. Scavuzzo, Matthew C. Hill, Jolanta Chmielowiec, Diane Yang, Jessica Teaw, Kuanwei Sheng, Yuelin Kong, Maria Bettini, Chenghang Zong, James F. Martin, Malgorzata Borowiak

Nat Commun. 2018; 9: 3356. Published online 2018 Aug 22. doi: 10.1038/s41467-018-05740-1

PMCID:: PMC6105717

Abstract Article PDF–14M

Select item 607014717.

Rbfox-Splicing Factors Maintain Skeletal Muscle Mass by Regulating Calpain3 and Proteostasis

Ravi K. Singh, Arseniy M. Kolonin, Marta L. Fiorotto, Thomas A. Cooper

Cell Rep. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Cell Rep. 2018 Jul 3; 24(1): 197–208. doi: 10.1016/j.celrep.2018.06.017

PMCID:: PMC6070147

Abstract Article PDF–936K

Select item 604272218.

Downregulation of splicing regulator RBFOX1 compromises visual depth perception

Lei Gu, Dean Bok, Fei Yu, Joseph Caprioli, Natik Piri

PLoS One. 2018; 13(7): e0200417. Published online 2018 Jul 12. doi: 10.1371/journal.pone.0200417

PMCID:: PMC6042722

Abstract Article PDF–29M

Select item 598926519.

Precise temporal regulation of alternative splicing during neural development

Sebastien M. Weyn-Vanhentenryck, Huijuan Feng, Dmytro Ustianenko, Rachel Duffié, Qinghong Yan, Martin Jacko, Jose C. Martinez, Marianne Goodwin, Xuegong Zhang, Ulrich Hengst, Stavros Lomvardas, Maurice S. Swanson, Chaolin Zhang

Nat Commun. 2018; 9: 2189. Published online 2018 Jun 6. doi: 10.1038/s41467-018-04559-0

PMCID:: PMC5989265

Abstract Article PDF–2.6M

Select item 582376220.

Rbfox splicing factors promote neuronal maturation and axon initial segment assembly

Martin Jacko, Sebastien M. Weyn-Vanhentenryck, John W. Smerdon, Rui Yan, Huijuan Feng, Damian J. Williams, Joy Pai, Ke Xu, Hynek Wichterle, Chaolin Zhang

Neuron. Author manuscript; available in PMC 2019 Feb 21.

Published in final edited form as: Neuron. 2018 Feb 21; 97(4): 853–868.e6. Published online 2018 Feb 1. doi: 10.1016/j.neuron.2018.01.020

PMCID:: PMC5823762

Abstract Article PDF–2.7M

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