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Select item 112583001.

Versatile nanobody-based approach to image, track and reconstitute functional Neurexin-1 in vivo

Rosario Vicidomini, Saumitra Dey Choudhury, Tae Hee Han, Tho Huu Nguyen, Peter Nguyen, Felipe Opazo, Mihaela Serpe

Nat Commun. 2024; 15: 6068. Published online 2024 Jul 18. doi: 10.1038/s41467-024-50462-2

PMCID:: PMC11258300

Abstract Article PDF–15M

Select item 111147342.

What model organisms and interactomics can reveal about the genetics of human obesity

Michael J. Williams, Markus S. Almén, Robert Fredriksson, Helgi B. Schiöth

Cell Mol Life Sci. 2012 Nov; 69(22): 3819–3834. Published online 2012 May 23. doi: 10.1007/s00018-012-1022-5

PMCID:: PMC11114734

Abstract Article PDF–614K

Select item 109319233.

The CHD Protein Kismet Restricts the Synaptic Localization of Cell Adhesion Molecules at the Drosophila Neuromuscular Junction

Ireland R. Smith, Emily L. Hendricks, Nina K. Latcheva, Daniel R. Marenda, Faith L. W. Liebl

Int J Mol Sci. 2024 Mar; 25(5): 3074. Published online 2024 Mar 6. doi: 10.3390/ijms25053074

PMCID:: PMC10931923

Abstract Article PDF–4.3M

Select item 107595164.

Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila

Gabrielle Lim-Kian-Siang, Arianna R. Izawa-Ishiguro, Yong Rao

Mol Brain. 2024; 17: 2. Published online 2024 Jan 2. doi: 10.1186/s13041-023-01073-3

PMCID:: PMC10759516

Abstract Article PDF–2.3M

Select item 106463375.

Neurexin and neuroligins jointly regulate synaptic degeneration at the Drosophila neuromuscular junction based on TEM studies

Gan Guangming, Chen Mei, Yu Qinfeng, Gao Xiang, Zhang Chenchen, Sheng Qingyuan, Xie Wei, Geng Junhua

Front Cell Neurosci. 2023; 17: 1257347. Published online 2023 Nov 1. doi: 10.3389/fncel.2023.1257347

PMCID:: PMC10646337

Abstract Article PDF–22M

Select item 105237616.

Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration

Marina L. Garcia-Vaquero, Marjorie Heim, Barbara Flix, Marcelo Pereira, Lucile Palin, Tânia M. Marques, Francisco R. Pinto, Javier de Las Rivas, Aaron Voigt, Florence Besse, Margarida Gama-Carvalho

BMC Genomics. 2023; 24: 576. Published online 2023 Sep 27. doi: 10.1186/s12864-023-09562-4

PMCID:: PMC10523761

Abstract Article PDF–3.2M

Select item 105020137.

Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster

Kristina Corthals, Vilma Andersson, Allison Churcher, Johan Reimegård, Anders Enjin

Sci Rep. 2023; 13: 15202. Published online 2023 Sep 14. doi: 10.1038/s41598-023-42506-2

PMCID:: PMC10502013

Abstract Article PDF–5.5M

Select item 104388408.

Growth deregulation and interaction with host hemocytes contribute to tumor progression in a Drosophila brain tumor model

Chrysanthi Voutyraki, Alexandros Choromidis, Anastasia Meligkounaki, Nikolaos Andreas Vlachopoulos, Vasiliki Theodorou, Sofia Grammenoudi, Emmanouil Athanasiadis, Sara Monticelli, Angela Giangrande, Christos Delidakis, Evanthia Zacharioudaki

Proc Natl Acad Sci U S A. 2023 Aug 15; 120(33): e2221601120. Published online 2023 Aug 7. doi: 10.1073/pnas.2221601120

PMCID:: PMC10438840

Abstract Article PDF–4.3M

Select item 104280719.

Neurofibromin 1 regulates early developmental sleep in Drosophila

Jaclyn Durkin, Amy R. Poe, Samuel J. Belfer, Anyara Rodriguez, Si Hao Tang, James A. Walker, Matthew S. Kayser

Neurobiol Sleep Circadian Rhythms. 2023 Nov; 15: 100101. Published online 2023 Aug 9. doi: 10.1016/j.nbscr.2023.100101

PMCID:: PMC10428071

Abstract Article PDF–8.8M

Select item 955883610.

Loss of neurexin-1 in Drosophila melanogaster results in altered energy metabolism and increased seizure susceptibility

Kyra A Levy, Eliana D Weisz, Thomas A Jongens

Hum Mol Genet. 2022 Oct 15; 31(20): 3422–3438. Published online 2022 May 25. doi: 10.1093/hmg/ddac115

PMCID:: PMC9558836

Abstract Article PDF–1.8M

Select item 948087711.

Drosophila Homolog of the Human Carpenter Syndrome Linked Gene, MEGF8, Is Required for Synapse Development and Function

Shuting Chen, Anand Venkatesan, Yong Qi Lin, Jing Xie, Gregory Neely, Swati Banerjee, Manzoor A. Bhat

J Neurosci. 2022 Sep 14; 42(37): 7016–7030. doi: 10.1523/JNEUROSCI.0442-22.2022

PMCID:: PMC9480877

Abstract Article PDF–5.3M

Select item 918842812.

A Quantitative Model of Sporadic Axonal Degeneration in the Drosophila Visual System

Mélisande Richard, Karolína Doubková, Yohei Nitta, Hiroki Kawai, Atsushi Sugie, Gaia Tavosanis

J Neurosci. 2022 Jun 15; 42(24): 4937–4952. doi: 10.1523/JNEUROSCI.2115-21.2022

PMCID:: PMC9188428

Abstract Article PDF–8.9M

Select item 906492913.

Synaptic Dysfunction Connects Autism Spectrum Disorder and Sleep Disturbances: A Perspective from Studies in Model Organisms

Fusun Doldur-Balli, Toshihiro Imamura, Olivia J. Veatch, Naihua N. Gong, Diane C. Lim, Michael P. Hart, Ted Abel, Matthew S. Kayser, Edward S. Brodkin, Allan I. Pack

Sleep Med Rev. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Sleep Med Rev. 2022 Apr; 62: 101595. Published online 2022 Jan 25. doi: 10.1016/j.smrv.2022.101595

PMCID:: PMC9064929

Abstract Article PDF–582K

Select item 863390314.

Neuroligin-1 Is a Mediator of Methylmercury Neuromuscular Toxicity

Jakob T Gunderson, Ashley E Peppriell, Ian N Krout, Daria Vorojeikina, Matthew D Rand

Toxicol Sci. 2021 Dec; 184(2): 236–251. Published online 2021 Sep 21. doi: 10.1093/toxsci/kfab114

PMCID:: PMC8633903

Abstract Article PDF–1.2M

Select item 852412915.

Genetic Transsynaptic Techniques for Mapping Neural Circuits in Drosophila

Lina Ni

Front Neural Circuits. 2021; 15: 749586. Published online 2021 Oct 4. doi: 10.3389/fncir.2021.749586

PMCID:: PMC8524129

Abstract Article PDF–1.4M

Select item 844244516.

The gut-microbiota-brain axis in autism: what Drosophila models can offer?

Safa Salim, Ayesha Banu, Amira Alwa, Swetha B. M. Gowda, Farhan Mohammad

J Neurodev Disord. 2021; 13: 37. Published online 2021 Sep 15. doi: 10.1186/s11689-021-09378-x

PMCID:: PMC8442445

Abstract Article PDF–1.9M

Select item 839183217.

Drosophila Models Rediscovered with Super-Resolution Microscopy

Szilárd Szikora, Péter Görög, Csaba Kozma, József Mihály

Cells. 2021 Aug; 10(8): 1924. Published online 2021 Jul 29. doi: 10.3390/cells10081924

PMCID:: PMC8391832

Abstract Article PDF–4.5M

Select item 824741318.

Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease

Young Won Kim, Ismael Al‐Ramahi, Amanda Koire, Stephen J. Wilson, Daniel M. Konecki, Samantha Mota, Shirin Soleimani, Juan Botas, Olivier Lichtarge

Alzheimers Dement. 2021 May; 17(5): 831–846. Published online 2020 Dec 7. doi: 10.1002/alz.12240

PMCID:: PMC8247413

Abstract Article PDF–1.9M

Select item 817789519.

Short and long sleeping mutants reveal links between sleep and macroautophagy

Joseph L Bedont, Hirofumi Toda, Mi Shi, Christine H Park, Christine Quake, Carly Stein, Anna Kolesnik, Amita Sehgal

eLife. 2021; 10: e64140. Published online 2021 Jun 4. doi: 10.7554/eLife.64140

PMCID:: PMC8177895

Abstract Article PDF–7.3M

Select item 814912520.

Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis

Tarik Seref Onur, Andrew Laitman, He Zhao, Ryan Keyho, Hyemin Kim, Jennifer Wang, Megan Mair, Huilan Wang, Lifang Li, Alma Perez, Maria de Haro, Ying-Wooi Wan, Genevera Allen, Boxun Lu, Ismael Al-Ramahi, Zhandong Liu, Juan Botas

eLife. 2021; 10: e64564. Published online 2021 Apr 19. doi: 10.7554/eLife.64564