PMC Links for GEO Profiles (Select 1747711) - PMC

Mar Puigdellívol, Stefan Milde, Anna Vilalta, Tom O.J. Cockram, David H. Allendorf, Jeffrey Y. Lee, Jacob M. Dundee, Katryna Pampuščenko, Vilmante Borutaite, Hugh N. Nuthall, Jack H. Brelstaff, Maria Grazia Spillantini, Guy C. Brown

Cell Rep. 2021 Dec 28; 37(13): 110148. Published online 2021 Dec 28. doi: 10.1016/j.celrep.2021.110148

PMCID:: PMC8733854

Abstract Article

Select item 85040614.

Inflammatory neuronal loss in the substantia nigra induced by systemic lipopolysaccharide is prevented by knockout of the P2Y₆ receptor in mice

Stefan Milde, Francesca W. van Tartwijk, Anna Vilalta, Tamara C. Hornik, Jacob M. Dundee, Mar Puigdellívol, Guy C. Brown

J Neuroinflammation. 2021; 18: 225. Published online 2021 Oct 11. doi: 10.1186/s12974-021-02280-2

PMCID:: PMC8504061

Abstract Article PDF–7.4M

Select item 81644755.

Microglia provide structural resolution to injured dendrites after severe seizures

Ukpong B. Eyo, Koichiro Haruwaka, Mingshu Mo, Antony Brayan Campos-Salazar, Lingxiao Wang, Xenophon S. Speros, IV, Sruchika Sabu, Pingyi Xu, Long-Jun Wu

Cell Rep. Author manuscript; available in PMC 2021 May 29.

Published in final edited form as: Cell Rep. 2021 May 4; 35(5): 109080. doi: 10.1016/j.celrep.2021.109080

PMCID:: PMC8164475

Abstract Article PDF–3.5M

Select item 77848456.

The UDP/P2y6 axis promotes lung metastasis of melanoma by remodeling the premetastatic niche

Juliang Qin, Zhen Zhang, Zhixiang Fu, Hua Ren, Mingyao Liu, Min Qian, Bing Du

Cell Mol Immunol. 2020 Dec; 17(12): 1269–1271. Published online 2020 Mar 6. doi: 10.1038/s41423-020-0392-0

PMCID:: PMC7784845

Article PDF–1.1M

Select item 77202047.

Lack of adipocyte purinergic P2Y₆ receptor greatly improves whole body glucose homeostasis

Shanu Jain, Sai P. Pydi, Kiran S. Toti, Bernard Robaye, Marco Idzko, Oksana Gavrilova, Jürgen Wess, Kenneth A. Jacobson

Proc Natl Acad Sci U S A. 2020 Dec 1; 117(48): 30763–30774. Published online 2020 Nov 16. doi: 10.1073/pnas.2006578117

PMCID:: PMC7720204

Abstract Article PDF–2.0M

Select item 74348758.

Modulation of P2Y₆R expression exacerbates pressure overload-induced cardiac remodeling in mice

Kakeru Shimoda, Akiyuki Nishimura, Caroline Sunggip, Tomoya Ito, Kazuhiro Nishiyama, Yuri Kato, Tomohiro Tanaka, Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Motohiro Nishida

Sci Rep. 2020; 10: 13926. Published online 2020 Aug 18. doi: 10.1038/s41598-020-70956-5

PMCID:: PMC7434875

Abstract Article PDF–3.1M

Select item 74159919.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 708043610.

P2Y6 receptor inhibition aggravates ischemic brain injury by reducing microglial phagocytosis

Ruo‐Xue Wen, Hui Shen, Shu‐Xian Huang, Li‐Ping Wang, Zong‐Wei Li, Peng Peng, Muyassar Mamtilahun, Yao‐Hui Tang, Fan‐Xia Shen, Heng‐Li Tian, Guo‐Yuan Yang, Zhi‐Jun Zhang

CNS Neurosci Ther. 2020 Apr; 26(4): 416–429. Published online 2020 Mar 10. doi: 10.1111/cns.13296

PMCID:: PMC7080436

Abstract Article PDF–3.1M

Select item 687731511.

P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation

Jun Nagai, Barbara Balestrieri, Laura B. Fanning, Timothy Kyin, Haley Cirka, Junrui Lin, Marco Idzko, Andreas Zech, Edy Y. Kim, Patrick J. Brennan, Joshua A. Boyce

J Clin Invest. 2019 Dec 2; 129(12): 5169–5186. Published online 2019 Oct 22. doi: 10.1172/JCI129761

PMCID:: PMC6877315

Abstract Article PDF–9.5M

Select item 583551312.

P2Y₆ Receptors Regulate CXCL10 Expression and Secretion in Mouse Intestinal Epithelial Cells

Mabrouka Salem, Alain Tremblay, Julie Pelletier, Bernard Robaye, Jean Sévigny

Front Pharmacol. 2018; 9: 149. Published online 2018 Feb 28. doi: 10.3389/fphar.2018.00149

PMCID:: PMC5835513

Abstract Article PDF–1.8M

Select item 544378313.

Prostaglandin E₂ glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y₆

Antje Brüser, Anne Zimmermann, Brenda C. Crews, Gregory Sliwoski, Jens Meiler, Gabriele M. König, Evi Kostenis, Vera Lede, Lawrence J. Marnett, Torsten Schöneberg

Sci Rep. 2017; 7: 2380. Published online 2017 May 24. doi: 10.1038/s41598-017-02414-8

PMCID:: PMC5443783

Abstract Article PDF–3.7M

Select item 542970614.

P2Y₆-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice

Satoru Kira, Mitsuharu Yoshiyama, Sachiko Tsuchiya, Eiji Shigetomi, Tatsuya Miyamoto, Hiroshi Nakagomi, Keisuke Shibata, Tsutomu Mochizuki, Masayuki Takeda, Schuichi Koizumi

Sci Rep. 2017; 7: 771. Published online 2017 Apr 10. doi: 10.1038/s41598-017-00824-2

PMCID:: PMC5429706

Abstract Article PDF–2.1M

Select item 535007315.

Central Role of P2Y₆ UDP Receptor in Arteriolar Myogenic Tone

Gilles Kauffenstein, Sophie Tamareille, Fabrice Prunier, Charlotte Roy, Audrey Ayer, Bertrand Toutain, Marie Billaud, Brant E. Isakson, Linda Grimaud, Laurent Loufrani, Pascal Rousseau, Pierre Abraham, Vincent Procaccio, Hannah Monyer, Cor de Wit, Jean-Marie Boeynaems, Bernard Robaye, Brenda R. Kwak, Daniel Henrion

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Aug; 36(8): 1598–1606. Published online 2016 Jun 2. doi: 10.1161/ATVBAHA.116.307739

PMCID:: PMC5350073

Abstract Article PDF–1.2M

Select item 530862516.

P2Y₆ contributes to ovalbumin-induced allergic asthma by enhancing mast cell function in mice

Jue-ping Shi, Shao-ying Wang, Li-li Chen, Xiao-yu Zhang, Yi-han Zhao, Bing Du, Wen-zheng Jiang, Min Qian, Hua Ren

Oncotarget. 2016 Sep 20; 7(38): 60906–60918. Published online 2016 Aug 31. doi: 10.18632/oncotarget.11758

PMCID:: PMC5308625

Abstract Article PDF–2.4M

Select item 495706517.

Loss of Mouse P2Y₆ Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy

Sophie Clouet, Larissa Di Pietrantonio, Evangelos-Panagiotis Daskalopoulos, Hrag Esfahani, Michael Horckmans, Marion Vanorlé, Anne Lemaire, Jean-Luc Balligand, Christophe Beauloye, Jean-Marie Boeynaems, Didier Communi

J Biol Chem. 2016 Jul 22; 291(30): 15841–15852. Published online 2016 May 26. doi: 10.1074/jbc.M115.684118

PMCID:: PMC4957065

Abstract Article PDF–3.3M

Select item 493710118.

P2Y6 Receptor-Mediated Microglial Phagocytosis in Radiation-Induced Brain Injury

Yongteng Xu, Weihan Hu, Yimin Liu, Pengfei Xu, Zichen Li, Rong Wu, Xiaolei Shi, Yamei Tang

Mol Neurobiol. 2016; 53(6): 3552–3564. Published online 2015 Jun 23. doi: 10.1007/s12035-015-9282-3

PMCID:: PMC4937101

Abstract Article PDF–1.8M

Select item 428020619.

Enhancement of Glucose Uptake in Mouse Skeletal Muscle Cells and Adipocytes by P2Y₆ Receptor Agonists

Ramachandran Balasubramanian, Bernard Robaye, Jean-Marie Boeynaems, Kenneth A. Jacobson

PLoS One. 2014; 9(12): e116203. Published online 2014 Dec 30. doi: 10.1371/journal.pone.0116203

PMCID:: PMC4280206

Abstract Article PDF–1001K

Select item 421608120.

P2Y₆ Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development

Ricardo A. Garcia, Mujing Yan, Debra Search, Rongan Zhang, Nancy L. Carson, Carol S. Ryan, Constance Smith-Monroy, Joanna Zheng, Jian Chen, Yan Kong, Huaping Tang, Samuel E. Hellings, Judith Wardwell-Swanson, Joseph E. Dinchuk, George C. Psaltis, David A. Gordon, Peter W. Glunz, Peter S. Gargalovic

PLoS One. 2014; 9(10): e111385. Published online 2014 Oct 31. doi: 10.1371/journal.pone.0111385

PMCID:: PMC4216081

Abstract Article PDF–1.9M

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