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Select item 101193151.

AGGF1 therapy inhibits thoracic aortic aneurysms by enhancing integrin α7-mediated inhibition of TGF-β1 maturation and ERK1/2 signaling

Xingwen Da, Ziyan Li, Xiaofan Huang, Zuhan He, Yubing Yu, Tongtong Tian, Chengqi Xu, Yufeng Yao, Qing K. Wang

Nat Commun. 2023; 14: 2265. Published online 2023 Apr 20. doi: 10.1038/s41467-023-37809-x

PMCID:: PMC10119315

Abstract Article PDF–11M

Select item 89686442.

Angiogenic factor AGGF1 blocks neointimal formation after vascular injury via interaction with integrin α7 on vascular smooth muscle cells

Yubing Yu, Yong Li, Huixin Peng, Qixue Song, Xingwen Da, Hui Li, Zuhan He, Xiang Ren, Chengqi Xu, Yufeng Yao, Qing K. Wang

J Biol Chem. 2022 Apr; 298(4): 101759. Published online 2022 Feb 22. doi: 10.1016/j.jbc.2022.101759

PMCID:: PMC8968644

Abstract Article PDF–4.3M

Select item 85805773.

Receptor and molecular mechanism of AGGF1 signaling in endothelial cell functions and angiogenesis

Jingjing Wang, Huixin Peng, Ayse Anil Timur, Vinay Pasupuleti, Yufeng Yao, Teng Zhang, Sun-Ah You, Chun Fan, Yubing Yu, Xinzhen Jia, Jing Chen, Chengqi Xu, Qiuyun Chen, Qing Wang

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Nov; 41(11): 2756–2769. Published online 2021 Sep 23. doi: 10.1161/ATVBAHA.121.316867

PMCID:: PMC8580577

Abstract Article PDF–1.4M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 71327946.

The 3′ Untranslated Region Protects the Heart from Angiotensin II-Induced Cardiac Dysfunction via AGGF1 Expression

Lexi Ding, Shan Lu, Yu Zhou, Dayin Lyu, Changhan Ouyang, Zejun Ma, Qiulun Lu

Mol Ther. 2020 Apr 8; 28(4): 1119–1132. Published online 2020 Feb 5. doi: 10.1016/j.ymthe.2020.02.002

PMCID:: PMC7132794

Abstract Article PDF–3.3M

Select item 69054887.

Angiogenic Factor AGGF1-Primed Endothelial Progenitor Cells Repair Vascular Defect in Diabetic Mice

Yufeng Yao, Yong Li, Qixue Song, Changqin Hu, Wen Xie, Chengqi Xu, Qiuyun Chen, Qing K. Wang

Diabetes. 2019 Aug; 68(8): 1635–1648. Published online 2019 May 15. doi: 10.2337/db18-1178

PMCID:: PMC6905488

Abstract Article PDF–2.7M

Select item 61031738.

Angiotensin II increases angiogenesis by NF-κB–mediated transcriptional activation of angiogenic factor AGGF1

Wenxia Si, Wen Xie, Wenbing Deng, Yi Xiao, Sadashiva S. Karnik, Chengqi Xu, Qiuyun Chen, Qing Kenneth Wang

FASEB J. 2018 Sep; 32(9): 5051–5062. Published online 2018 Apr 11. doi: 10.1096/fj.201701543RR

PMCID:: PMC6103173

Abstract Article

Select item 60786409.

Haploinsufficiency of Klippel-Trenaunay syndrome gene Aggf1 inhibits developmental and pathological angiogenesis by inactivating PI3K and AKT and disrupts vascular integrity by activating VE-cadherin

Teng Zhang, Yufeng Yao, Jingjing Wang, Yong Li, Ping He, Vinay Pasupuleti, Zhengkun Hu, Xinzhen Jia, Qixue Song, Xiao-Li Tian, Changqing Hu, Qiuyun Chen, Qing Kenneth Wang

Hum Mol Genet. 2016 Dec 1; 25(23): 5094–5110. Published online 2016 Aug 13. doi: 10.1093/hmg/ddw273

PMCID:: PMC6078640

Abstract Article PDF–1.4M

Select item 566918810.

Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury

Yufeng Yao, Zhenkun Hu, Jian Ye, Changqing Hu, Qixue Song, Xingwen Da, Yubin Yu, Hui Li, Chengqi Xu, Qiuyun Chen, Qing Kenneth Wang

J Am Heart Assoc. 2017 Jun; 6(6): e005889. Published online 2017 Jun 25. doi: 10.1161/JAHA.117.005889

PMCID:: PMC5669188

Abstract Article PDF–2.2M

Select item 552710711.

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure

Yufeng Yao, Qiulun Lu, Zhenkun Hu, Yubin Yu, Qiuyun Chen, Qing K. Wang

Nat Commun. 2017; 8: 133. Published online 2017 Jul 25. doi: 10.1038/s41467-017-00171-w

PMCID:: PMC5527107

Abstract Article PDF–3.3M

Select item 498137512.

Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart Disease

Qiulun Lu, Yufeng Yao, Zhenkun Hu, Changqing Hu, Qixue Song, Jian Ye, Chengqi Xu, Annabel Z. Wang, Qiuyun Chen, Qing Kenneth Wang

PLoS Biol. 2016 Aug; 14(8): e1002529. Published online 2016 Aug 11. doi: 10.1371/journal.pbio.1002529

PMCID:: PMC4981375

Abstract Article PDF–11M

Select item 347910213.

Angiogenic Factor AGGF1 Promotes Therapeutic Angiogenesis in a Mouse Limb Ischemia Model

Qiulun Lu, Yihong Yao, Yufeng Yao, Shizhi Liu, Yuan Huang, Shan Lu, Ying Bai, Bisheng Zhou, Yan Xu, Lei Li, Nan Wang, Li Wang, Jie Zhang, Xiang Cheng, Gangjian Qin, Wei Ma, Chengqi Xu, Xin Tu, Qing Wang

PLoS One. 2012; 7(10): e46998. Published online 2012 Oct 23. doi: 10.1371/journal.pone.0046998

PMCID:: PMC3479102

Abstract Article PDF–817K

Select item 343984514.

A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract

Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith

Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130

PMCID:: PMC3439845

Abstract Article PDF–1.4M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 315221016.

Sphingolipid modulation of angiogenic factor expression in neuroblastoma

Mei-Hong Li, Timothy Hla, Fernando Ferrer

Cancer Prev Res (Phila) Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Cancer Prev Res (Phila). 2011 Aug; 4(8): 1325–1332. Published online 2011 May 16. doi: 10.1158/1940-6207.CAPR-11-0017

PMCID:: PMC3152210

Abstract Article PDF–1.0M

Select item 161887317.

Identification of an angiogenic factor that when mutated causes susceptibility to Klippel–Trenaunay syndrome

Xiao-Li Tian, Rajkumar Kadaba, Sun-Ah You, Mugen Liu, Ayse Anil Timur, Lin Yang, Qiuyun Chen, Przemyslaw Szafranski, Shaoqi Rao, Ling Wu, David E. Housman, Paul E. DiCorleto, David J. Driscoll, Julian Borrow, Qing Wang

Nature. Author manuscript; available in PMC 2006 Oct 23.

Published in final edited form as: Nature. 2004 Feb 12; 427(6975): 640–645. doi: 10.1038/nature02320.

PMCID:: PMC1618873

Abstract Article PDF–1.2M

Select item 119959118.

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain

Adrienne E McKee, Emmanuel Minet, Charlene Stern, Shervin Riahi, Charles D Stiles, Pamela A Silver

BMC Dev Biol. 2005; 5: 14. Published online 2005 Jul 20. doi: 10.1186/1471-213X-5-14

PMCID:: PMC1199591

Abstract Article PDF–2.0M

Select item 52892819.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 40380320.

Characterizing Embryonic Gene Expression Patterns in the Mouse Using Nonredundant Sequence-Based Selection

Rita Sousa-Nunes, Amer Ahmed Rana, Ross Kettleborough, Joshua M. Brickman, Melanie Clements, Alistair Forrest, Sean Grimmond, Philip Avner, James C. Smith, Sally L. Dunwoodie, Rosa S.P. Beddington

Genome Res. 2003 Dec; 13(12): 2609–2620. doi: 10.1101/gr.1362303

PMCID:: PMC403803

Abstract Article PDF–908K

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