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Select item 107034191.

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves

Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J. Cockell, Maureen A. Kane, Steven Lisgo, Deborah J. Henderson

PLoS Genet. 2023 Nov; 19(11): e1010777. Published online 2023 Nov 27. doi: 10.1371/journal.pgen.1010777

PMCID:: PMC10703419

Abstract Article PDF–9.6M

Select item 105925092.

Transcriptional dynamics of delaminating neuroblasts in the mouse otic vesicle

Maggie S. Matern, Robert Durruthy-Durruthy, Onur Birol, Spyros Darmanis, Mirko Scheibinger, Andrew K. Groves, Stefan Heller

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112545. Published online 2023 May 23. doi: 10.1016/j.celrep.2023.112545

PMCID:: PMC10592509

Abstract Article PDF–3.8M

Select item 84412033.

Retinoic acid exerts sexually dimorphic effects on muscle energy metabolism and function

Yaxin Zhao, Marta Vuckovic, Hong Sik Yoo, Nina Fox, Adrienne Rodriguez, Kyler McKessy, Joseph L. Napoli

J Biol Chem. 2021 Sep; 297(3): 101101. Published online 2021 Aug 19. doi: 10.1016/j.jbc.2021.101101

PMCID:: PMC8441203

Abstract Article PDF–4.1M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82994185.

Branchiomeric Muscle Development Requires Proper Retinoic Acid Signaling

Qi Wang, Lin Xu, Jiro Miura, Mithun Kumar Saha, Yume Uemura, Lisa L. Sandell, Paul A. Trainor, Takashi Yamashiro, Hiroshi Kurosaka

Front Cell Dev Biol. 2021; 9: 596838. Published online 2021 Jul 9. doi: 10.3389/fcell.2021.596838

PMCID:: PMC8299418

Abstract Article PDF–7.0M

Select item 79491016.

Changes in retinoid metabolism and signaling associated with metabolic remodeling during fasting and in type I diabetes

Alla V. Klyuyeva, Olga V. Belyaeva, Kelli R. Goggans, Wojciech Krezel, Kirill M. Popov, Natalia Y. Kedishvili

J Biol Chem. 2021 Jan-Jun; 296: 100323. Published online 2021 Jan 22. doi: 10.1016/j.jbc.2021.100323

PMCID:: PMC7949101

Abstract Article PDF–2.9M

Select item 77078517.

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit

Glenda Evangelina Comai, Markéta Tesařová, Valérie Dupé, Muriel Rhinn, Pedro Vallecillo-García, Fabio da Silva, Betty Feret, Katherine Exelby, Pascal Dollé, Leif Carlsson, Brian Pryce, François Spitz, Sigmar Stricker, Tomáš Zikmund, Jozef Kaiser, James Briscoe, Andreas Schedl, Norbert B. Ghyselinck, Ronen Schweitzer, Shahragim Tajbakhsh

PLoS Biol. 2020 Nov; 18(11): e3000902. Published online 2020 Nov 17. doi: 10.1371/journal.pbio.3000902

PMCID:: PMC7707851

Abstract Article PDF–5.0M

Select item 74208398.

Retinoic acid synthesis and autoregulation mediate zonal patterning of vestibular organs and inner ear morphogenesis

Kazuya Ono, Lisa L. Sandell, Paul A. Trainor, Doris K. Wu

Development. 2020 Aug 1; 147(15): dev192070. Published online 2020 Aug 7. doi: 10.1242/dev.192070

PMCID:: PMC7420839

Abstract Article

Select item 68512909.

Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands

Lizhi Wu, Olga V. Belyaeva, Mark K. Adams, Alla V. Klyuyeva, Seung-Ah Lee, Kelli R. Goggans, Robert A. Kesterson, Kirill M. Popov, Natalia Y. Kedishvili

J Biol Chem. 2019 Nov 8; 294(45): 17060–17074. Published online 2019 Sep 27. doi: 10.1074/jbc.RA119.010835

PMCID:: PMC6851290

Abstract Article PDF–3.5M

Select item 667938310.

RDH10 function is necessary for spontaneous fetal mouth movement that facilitates palate shelf elevation

Regina M. Friedl, Swetha Raja, Melissa A. Metzler, Niti D. Patel, Kenneth R. Brittian, Steven P. Jones, Lisa L. Sandell

Dis Model Mech. 2019 Jul 1; 12(7): dmm039073. Published online 2019 Jul 3. doi: 10.1242/dmm.039073

PMCID:: PMC6679383

Abstract Article

Select item 662924011.

Tie2 regulates endocardial sprouting and myocardial trabeculation

Xianghu Qu, Cristina Harmelink, H. Scott Baldwin

JCI Insight. 2019 Jul 11; 4(13): e96002. Published online 2019 Jul 11. doi: 10.1172/jci.insight.96002

PMCID:: PMC6629240

Abstract Article PDF–60M

Select item 653133512.

RDH1 suppresses adiposity by promoting brown adipose adaptation to fasting and re-feeding

Charles R. Krois, Marta G. Vuckovic, Priscilla Huang, Claire Zaversnik, Conan S. Liu, Candice E. Gibson, Madelyn R. Wheeler, Kristin M. Obrochta, Jin H. Min, Candice B. Herber, Airlia C. Thompson, Ishan D. Shah, Sean P. Gordon, Marc K. Hellerstein, Joseph L. Napoli

Cell Mol Life Sci. 2019 Jun; 76(12): 2425–2447. Published online 2019 Feb 20. doi: 10.1007/s00018-019-03046-z

PMCID:: PMC6531335

Abstract Article PDF–10M

Select item 629007913.

Retinoic Acid Regulates Endothelial β-catenin Expression and Pericyte Numbers in the Developing Brain Vasculature

Stephanie Bonney, Brenna J. C. Dennison, Megan Wendlandt, Julie A. Siegenthaler

Front Cell Neurosci. 2018; 12: 476. Published online 2018 Dec 5. doi: 10.3389/fncel.2018.00476

PMCID:: PMC6290079

Abstract Article PDF–9.1M

Select item 614177114.

Correction: RDH10-mediated retinol metabolism and RARα-mediated retinoic acid signaling are required for submandibular salivary gland initiation (doi: 10.1242/dev.164822)

Melissa A. Metzler, Swetha Raja, Kelsey H. Elliott, Regina M. Friedl, Nhut Quang Huy Tran, Samantha A. Brugmann, Melinda Larsen, Lisa L. Sandell

Development. 2018 Sep 1; 145(17): dev170795. Published online 2018 Aug 30. doi: 10.1242/dev.170795

Corrects:: Development. 2018 Aug 1; 145(15): dev164822.

PMCID:: PMC6141771

Correction

Select item 611014415.

RDH10-mediated retinol metabolism and RARα-mediated retinoic acid signaling are required for submandibular salivary gland initiation

Melissa A. Metzler, Swetha Raja, Kelsey H. Elliott, Regina M. Friedl, Nhut Quang Huy Tran, Samantha A. Brugmann, Melinda Larsen, Lisa L. Sandell

Development. 2018 Aug 1; 145(15): dev164822. Published online 2018 Aug 2. doi: 10.1242/dev.164822

Correction in:: Development. 2018 Sep 1; 145(17): dev170795.

PMCID:: PMC6110144

Abstract Article

Select item 599898216.

Retinoic acid signaling promotes the cytoskeletal rearrangement of embryonic epicardial cells

Suya Wang, Jianshi Yu, Jace W. Jones, Keely Pierzchalski, Maureen A. Kane, Paul A. Trainor, José Xavier-Neto, Alexander R. Moise

FASEB J. 2018 Jul; 32(7): 3765–3781. Published online 2018 Feb 15. doi: 10.1096/fj.201701038R

PMCID:: PMC5998982

Abstract Article

Select item 586085817.

Modest Decreases in Endogenous All-trans-Retinoic Acid Produced by a Mouse Rdh10 Heterozygote Provoke Major Abnormalities in Adipogenesis and Lipid Metabolism

Di Yang, Marta G. Vuckovic, Carolyn P. Smullin, Myeongcheol Kim, Christabel Pui-See Lo, Emily Devericks, Hong Sik Yoo, Milena Tintcheva, Yinghua Deng, Joseph L. Napoli

Diabetes. 2018 Apr; 67(4): 662–673. Published online 2018 Jan 10. doi: 10.2337/db17-0946

PMCID:: PMC5860858

Abstract Article PDF–3.0M

Select item 544649018.

Differential Effects of Retinoic Acid Concentrations in Regulating Blood–Brain Barrier Properties

Stephanie Bonney, Julie A. Siegenthaler

eNeuro. 2017 May-Jun; 4(3): ENEURO.0378-16.2017. Prepublished online 2017 May 16. Published online 2017 May 26. doi: 10.1523/ENEURO.0378-16.2017

PMCID:: PMC5446490

Abstract Article PDF–5.2M

Select item 544384319.

The role of retinol dehydrogenase 10 in the cone visual cycle

Yunlu Xue, Shinya Sato, David Razafsky, Bhubanananda Sahu, Susan Q. Shen, Chloe Potter, Lisa L. Sandell, Joseph C. Corbo, Krzysztof Palczewski, Akiko Maeda, Didier Hodzic, Vladimir J. Kefalov

Sci Rep. 2017; 7: 2390. Published online 2017 May 24. doi: 10.1038/s41598-017-02549-8