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Items: 15

1.
Structure of phospholipase Cε reveals an integrated RA1 domain and previously unidentified regulatory elements
Ngango Y. Rugema, Elisabeth E. Garland-Kuntz, Monita Sieng, Kaushik Muralidharan, Michelle M. Van Camp, Hannah O’Neill, William Mbongo, Arielle F. Selvia, Andrea T. Marti, Amanda Everly, Emmanda McKenzie, Angeline M. Lyon
Commun Biol. 2020; 3: 445. Published online 2020 Aug 14. doi: 10.1038/s42003-020-01178-8
PMCID:
PMC7427993
AbstractArticlePDF–1.2M
2.
Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy
Craig A Nash, Wenhui Wei, Roshanak Irannejad, Alan V Smrcka
eLife. 2019; 8: e48167. Published online 2019 Aug 21. doi: 10.7554/eLife.48167
PMCID:
PMC6726460
AbstractArticlePDF–2.9M
3.
PLCE1 promotes myocardial ischemia–reperfusion injury in H/R H9c2 cells and I/R rats by promoting inflammation
WenHua Li, Yong Li, Ying Chu, WeiMin Wu, QiuHua Yu, XiaoBo Zhu, Qiang Wang
Biosci Rep. 2019 Jul 31; 39(7): BSR20181613. Prepublished online 2019 Jun 19. Published online 2019 Jul 5. doi: 10.1042/BSR20181613
PMCID:
PMC6609553
AbstractArticlePDF–1.2M
4.
Compartmentalized Cyclic Nucleotides Have Opposing Effects on Regulation of Hypertrophic Phospholipase Cε Signaling in Cardiac Myocytes
Craig A. Nash, Loren M. Brown, Sundeep Malik, Xiaodong Cheng, Alan V. Smrcka
J Mol Cell Cardiol. Author manuscript; available in PMC 2019 Aug 1.
Published in final edited form as: J Mol Cell Cardiol. 2018 Aug; 121: 51–59. Published online 2018 Jun 7. doi: 10.1016/j.yjmcc.2018.06.002
PMCID:
PMC6373484
AbstractArticlePDF–1.3M
5.
FMRP recruitment of β‐catenin to the translation pre‐initiation complex represses translation
Saviz Ehyai, Tetsuaki Miyake, Declan Williams, Jyotsna Vinayak, Mark A Bayfield, John C McDermott
EMBO Rep. 2018 Dec; 19(12): e45536. Published online 2018 Oct 25. doi: 10.15252/embr.201745536
PMCID:
PMC6280795
AbstractArticlePDF–3.4M
6.
G protein βγ subunits directly interact with and activate phospholipase Cϵ
Jerry C. Madukwe, Elisabeth E. Garland-Kuntz, Angeline M. Lyon, Alan V. Smrcka
J Biol Chem. 2018 Apr 27; 293(17): 6387–6397. Published online 2018 Mar 13. doi: 10.1074/jbc.RA118.002354
PMCID:
PMC5925795
AbstractArticlePDF–2.6M
7.
Advillin acts upstream of phospholipase C ϵ1 in steroid-resistant nephrotic syndrome
Jia Rao, Shazia Ashraf, Weizhen Tan, Amelie T. van der Ven, Heon Yung Gee, Daniela A. Braun, Krisztina Fehér, Sudeep P. George, Amin Esmaeilniakooshkghazi, Won-Il Choi, Tilman Jobst-Schwan, Ronen Schneider, Johanna Magdalena Schmidt, Eugen Widmeier, Jillian K. Warejko, Tobias Hermle, David Schapiro, Svjetlana Lovric, Shirlee Shril, Ankana Daga, Ahmet Nayir, Mohan Shenoy, Yincent Tse, Martin Bald, Udo Helmchen, Sevgi Mir, Afig Berdeli, Jameela A. Kari, Sherif El Desoky, Neveen A. Soliman, Arvind Bagga, Shrikant Mane, Mohamad A. Jairajpuri, Richard P. Lifton, Seema Khurana, Jose C. Martins, Friedhelm Hildebrandt
J Clin Invest. 2017 Dec 1; 127(12): 4257–4269. Published online 2017 Oct 23. doi: 10.1172/JCI94138
PMCID:
PMC5707164
AbstractArticlePDF–11M
8.
Phospholipase Cε Modulates Rap1 Activity and the Endothelial Barrier
Peter V. DiStefano, Alan V. Smrcka, Angela J. Glading
PLoS One. 2016; 11(9): e0162338. Published online 2016 Sep 9. doi: 10.1371/journal.pone.0162338
PMCID:
PMC5017709
AbstractArticlePDF–6.0M
9.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
10.
Phospholipase Cϵ Scaffolds to Muscle-specific A Kinase Anchoring Protein (mAKAPβ) and Integrates Multiple Hypertrophic Stimuli in Cardiac Myocytes
Lianghui Zhang, Sundeep Malik, Grant G. Kelley, Michael S. Kapiloff, Alan V. Smrcka
J Biol Chem. 2011 Jul 1; 286(26): 23012–23021. Published online 2011 May 5. doi: 10.1074/jbc.M111.231993
PMCID:
PMC3123069
AbstractArticlePDF–2.4M
11.
Dual Activation of Phospholipase C-ε by Rho and Ras GTPases
Jason P. Seifert, Yixing Zhou, Stephanie N. Hicks, John Sondek, T. Kendall Harden
J Biol Chem. 2008 Oct 31; 283(44): 29690–29698. doi: 10.1074/jbc.M805038200
PMCID:
PMC2573092
AbstractArticlePDF–489K
12.
G-protein-coupled Receptor Agonists Activate Endogenous Phospholipase Cε and Phospholipase Cβ3 in a Temporally Distinct Manner
Grant G. Kelley, Katherine A. Kaproth-Joslin, Sarah E. Reks, Alan V. Smrcka, Richard J. H. Wojcikiewicz
J Biol Chem. Author manuscript; available in PMC 2006 Jun 28.
Published in final edited form as: J Biol Chem. 2006 Feb 3; 281(5): 2639–2648. Published online 2005 Nov 28. doi: 10.1074/jbc.M507681200
PMCID:
PMC1483126
AbstractArticlePDF–533K
13.
Identification of a novel cytosolic poly-phosphoinositide-specific phospholipase C (PLC-86) as the major G-protein-regulated enzyme.
G M Thomas, B Geny, S Cockcroft
EMBO J. 1991 Sep; 10(9): 2507–2512. doi: 10.1002/j.1460-2075.1991.tb07790.x
PMCID:
PMC452947
SummaryPage BrowsePDF–1.0M
14.
Activation of CD4 T cells by Raf-independent effectors of Ras
Jan Czyzyk, Jennifer L. Brogdon, Abdallah Badou, Octavian Henegariu, Paula Preston Hurlburt, Richard Flavell, Kim Bottomly
Proc Natl Acad Sci U S A. 2003 May 13; 100(10): 6003–6008. Published online 2003 Apr 29. doi: 10.1073/pnas.1031494100
PMCID:
PMC156316
AbstractArticlePDF–353K
15.
Phospholipase Cε: a novel Ras effector
Grant G. Kelley, Sarah E. Reks, Joanne M. Ondrako, Alan V. Smrcka
EMBO J. 2001 Feb 15; 20(4): 743–754. doi: 10.1093/emboj/20.4.743
PMCID:
PMC145421
AbstractArticlePDF–574K

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