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Items: 1 to 20 of 29

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice
Sachiko Noda, Shigeto Sato, Takahiro Fukuda, Shinichi Ueno, Norihiro Tada, Nobutaka Hattori
Mol Brain. 2022; 15: 54. Published online 2022 Jun 14. doi: 10.1186/s13041-022-00936-5
PMCID:
PMC9199167
AbstractArticlePDF–1.3M
3.
Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells
Rebecca Harris, Ming Yang, Christina Schmidt, Chloe Royet, Sarbjit Singh, Amarnath Natarajan, May Morris, Christian Frezza, Heike Laman
J Cell Biol. 2022 Jul 4; 221(7): e202203095. Published online 2022 Jun 7. doi: 10.1083/jcb.202203095
PMCID:
PMC9178409
AbstractArticlePDF–4.3M
4.
FBXO7 triggers caspase 8-mediated proteolysis of the transcription factor FOXO4 and exacerbates neuronal cytotoxicity
Su Hyoun Lee, Sungyeon Jung, Yun Ju Lee, Minju Hyun, Kwang Chul Chung
J Biol Chem. 2021 Dec; 297(6): 101426. Published online 2021 Nov 17. doi: 10.1016/j.jbc.2021.101426
PMCID:
PMC8665361
AbstractArticlePDF–2.5M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Fbxo7 and Pink1 play a reciprocal role in regulating their protein levels
Tianwen Huang, Lijun Fang, Raoli He, Huidan Weng, Xiaochun Chen, Qinyong Ye, Dianbo Qu
Aging (Albany NY) 2021 Jan 15; 13(1): 77–88. Published online 2020 Dec 3. doi: 10.18632/aging.202236
PMCID:
PMC7835017
AbstractArticlePDF–2.7M
7.
Chemical inhibition of FBXO7 reduces inflammation and confers neuroprotection by stabilizing the mitochondrial kinase PINK1
Yuan Liu, Travis B. Lear, Manish Verma, Kent Z.Q. Wang, P. Anthony Otero, Alison C. McKelvey, Sarah R. Dunn, Erin Steer, Nicholas W. Bateman, Christine Wu, Yu Jiang, Nathaniel M. Weathington, Mauricio Rojas, Charleen T. Chu, Bill B. Chen, Rama K. Mallampalli
JCI Insight. 2020 Jun 4; 5(11): e131834. Published online 2020 Jun 4. doi: 10.1172/jci.insight.131834
PMCID:
PMC7308049
AbstractArticlePDF–16M
8.
A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation
Louise van der Weyden, Agnieszka Swiatkowska, Vivek Iyer, Anneliese O. Speak, David J. Adams
G3 (Bethesda) 2020 Jun; 10(6): 1869–1877. Published online 2020 Apr 3. doi: 10.1534/g3.120.401128
PMCID:
PMC7263671
AbstractArticlePDF–1.0M
9.
A Conserved Requirement for Fbxo7 During Male Germ Cell Cytoplasmic Remodeling
Claudia C. Rathje, Suzanne J. Randle, Sara Al Rawi, Benjamin M. Skinner, David E. Nelson, Antara Majumdar, Emma E. P. Johnson, Joanne Bacon, Myrto Vlazaki, Nabeel A. Affara, Peter J. Ellis, Heike Laman
Front Physiol. 2019; 10: 1278. Published online 2019 Oct 10. doi: 10.3389/fphys.2019.01278
PMCID:
PMC6795710
AbstractArticlePDF–6.1M
10.
Loss of FBXO7 results in a Parkinson's‐like dopaminergic degeneration via an RPL23–MDM2–TP53 pathway
Simon RW Stott, Suzanne J Randle, Sara Al Rawi, Paulina A Rowicka, Rebecca Harris, Bethany Mason, Jing Xia, Jeffrey W Dalley, Roger A Barker, Heike Laman
J Pathol. 2019 Oct; 249(2): 241–254. Published online 2019 Aug 6. doi: 10.1002/path.5312
PMCID:
PMC6790581
AbstractArticlePDF–7.7M
11.
Myelinating Glia-Specific Deletion of Fbxo7 in Mice Triggers Axonal Degeneration in the Central Nervous System Together with Peripheral Neuropathy
Sabitha Joseph, Siv Vingill, Olaf Jahn, Robert Fledrich, Hauke B. Werner, Istvan Katona, Wiebke Möbius, Mišo Mitkovski, Yuhao Huang, Joachim Weis, Michael W. Sereda, Jörg B. Schulz, Klaus-Armin Nave, Judith Stegmüller
J Neurosci. 2019 Jul 10; 39(28): 5606–5626. doi: 10.1523/JNEUROSCI.3094-18.2019
PMCID:
PMC6616290
AbstractArticlePDF–7.2M
12.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
13.
FBXO7 sensitivity of phenotypic traits elucidated by a hypomorphic allele
Carmen Ballesteros Reviriego, Simon Clare, Mark J. Arends, Emma L. Cambridge, Agnieszka Swiatkowska, Susana Caetano, Bushra Abu-Helil, Leanne Kane, Katherine Harcourt, David A. Goulding, Diane Gleeson, Edward Ryder, Brendan Doe, Jacqueline K. White, Louise van der Weyden, Gordon Dougan, David J. Adams, Anneliese O. Speak
PLoS One. 2019; 14(3): e0212481. Published online 2019 Mar 6. doi: 10.1371/journal.pone.0212481
PMCID:
PMC6402633
AbstractArticlePDF–4.0M
14.
Opposing effects on the cell cycle of T lymphocytes by Fbxo7 via Cdk6 and p27
Shachi P. Patel, Suzanne J. Randle, Sarah Gibbs, Anne Cooke, Heike Laman
Cell Mol Life Sci. 2017 Apr; 74(8): 1553–1566. Published online 2016 Dec 3. doi: 10.1007/s00018-016-2427-3
PMCID:
PMC5357273
AbstractArticlePDF–1018K
15.
Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism‐like phenotype in mice
Siv Vingill, David Brockelt, Camille Lancelin, Lars Tatenhorst, Guergana Dontcheva, Christian Preisinger, Nicola Schwedhelm‐Domeyer, Sabitha Joseph, Miso Mitkovski, Sandra Goebbels, Klaus‐Armin Nave, Jörg B Schulz, Till Marquardt, Paul Lingor, Judith Stegmüller
EMBO J. 2016 Sep 15; 35(18): 2008–2025. Published online 2016 Aug 6. doi: 10.15252/embj.201593585
PMCID:
PMC5282834
AbstractArticlePDF–3.1M
16.
Genomic Profiling of Patient-Derived Colon Cancer Xenograft Models
Won-Suk Lee, Hye-Youn Kim, Jae Yeon Seok, Ho Hee Jang, Yeon Ho Park, So-Young Kim, Dong Bok Shin, Suntaek Hong
Medicine (Baltimore) 2014 Dec; 93(28): e298. Published online 2014 Dec 2. doi: 10.1097/MD.0000000000000298
PMCID:
PMC4603094
AbstractArticlePDF–581K
17.
Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression
Suzanne J Randle, David E Nelson, Shachi P Patel, Heike Laman
J Pathol. 2015 Oct; 237(2): 263–272. Published online 2015 Jul 8. doi: 10.1002/path.4571
PMCID:
PMC4583784
AbstractArticlePDF–1.7M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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