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Select item 106510921.

A Drosophila model targets Eiger/TNFα to alleviate obesity-related insulin resistance and macrophage infiltration

Zhasmine Mirzoyan, Alice Valenza, Sheri Zola, Carola Bonfanti, Lorenzo Arnaboldi, Nicholas Ferrari, John Pollard, Valeria Lupi, Matteo Cassinelli, Matteo Frattaroli, Mehtap Sahin, Maria Enrica Pasini, Paola Bellosta

Dis Model Mech. 2023 Nov 1; 16(11): dmm050388. Published online 2023 Nov 6. doi: 10.1242/dmm.050388

PMCID:: PMC10651092

Abstract Article

Select item 97894022.

Reduction of nucleolar NOC1 leads to the accumulation of pre-rRNAs and induces Xrp1, affecting growth and resulting in cell competition

Francesca Destefanis, Valeria Manara, Stefania Santarelli, Sheri Zola, Marco Brambilla, Giacomo Viola, Paola Maragno, Ilaria Signoria, Gabriella Viero, Maria Enrica Pasini, Marianna Penzo, Paola Bellosta

J Cell Sci. 2022 Dec 1; 135(23): jcs260110. Published online 2022 Dec 7. doi: 10.1242/jcs.260110

PMCID:: PMC9789402

Abstract Article

Select item 86644863.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 86293954.

A large-scale transgenic RNAi screen identifies transcription factors that modulate myofiber size in Drosophila

Flavia A. Graca, Natalie Sheffield, Melissa Puppa, David Finkelstein, Liam C. Hunt, Fabio Demontis

PLoS Genet. 2021 Nov; 17(11): e1009926. Published online 2021 Nov 15. doi: 10.1371/journal.pgen.1009926

PMCID:: PMC8629395

Abstract Article PDF–2.3M

Select item 70624665.

A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

Fillip Port, Claudia Strein, Mona Stricker, Benedikt Rauscher, Florian Heigwer, Jun Zhou, Celine Beyersdörffer, Jana Frei, Amy Hess, Katharina Kern, Laura Lange, Nora Langner, Roberta Malamud, Bojana Pavlović, Kristin Rädecke, Lukas Schmitt, Lukas Voos, Erica Valentini, Michael Boutros

eLife. 2020; 9: e53865. Published online 2020 Feb 13. doi: 10.7554/eLife.53865

PMCID:: PMC7062466

Abstract Article PDF–3.4M

Select item 69615786.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 64859567.

A Comprehensive Drosophila melanogaster Transcription Factor Interactome

Leila Shokri, Sachi Inukai, Antonina Hafner, Kathryn Weinand, Korneel Hens, Anastasia Vedenko, Stephen S. Gisselbrecht, Riccardo Dainese, Johannes Bischof, Edy Furger, Jean-Daniel Feuz, Konrad Basler, Bart Deplancke, Martha L. Bulyk

Cell Rep. Author manuscript; available in PMC 2019 Apr 26.

Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 955–970.e7. doi: 10.1016/j.celrep.2019.03.071

PMCID:: PMC6485956

Abstract Article PDF–1.6M

Select item 58676048.

Anthocyanins Function as Anti-Inflammatory Agents in a Drosophila Model for Adipose Tissue Macrophage Infiltration

Alice Valenza, Carola Bonfanti, Maria Enrica Pasini, Paola Bellosta

Biomed Res Int. 2018; 2018: 6413172. Published online 2018 Mar 12. doi: 10.1155/2018/6413172

PMCID:: PMC5867604

Abstract Article PDF–2.0M

Select item 57078059.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900210.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 512686411.

Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster

Punita Juneja, Andrew Quinn, Francis M. Jiggins

BMC Genomics. 2016; 17: 981. Published online 2016 Nov 28. doi: 10.1186/s12864-016-3333-7

PMCID:: PMC5126864

Abstract Article PDF–1.1M

Select item 488965812.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 478811613.

Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, Halyna R. Shcherbata

Genetics. 2016 Mar; 202(3): 1167–1183. Published online 2016 Jan 22. doi: 10.1534/genetics.115.185371

PMCID:: PMC4788116

Abstract Article PDF–4.7M

Select item 473800514.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 468210115.

The genetic basis of natural variation in mushroom body size in Drosophila melanogaster

Liesbeth Zwarts, Lies Vanden Broeck, Elisa Cappuyns, Julien F. Ayroles, Michael M. Magwire, Veerle Vulsteke, Jason Clements, Trudy F. C. Mackay, Patrick Callaerts

Nat Commun. 2015; 6: 10115. Published online 2015 Dec 11. doi: 10.1038/ncomms10115

PMCID:: PMC4682101

Abstract Article PDF–2.0M

Select item 452833016.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832917.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 441435418.

The Pentameric Nucleoplasmin Fold Is Present in Drosophila FKBP39 and a Large Number of Chromatin-Related Proteins

Christian Edlich-Muth, Jean-Baptiste Artero, Phil Callow, Marcin R. Przewloka, Aleksandra A. Watson, Wei Zhang, David M. Glover, Janusz Debski, Michal Dadlez, Adam R. Round, V. Trevor Forsyth, Ernest D. Laue

J Mol Biol. 2015 May 22; 427(10): 1949–1963. doi: 10.1016/j.jmb.2015.03.010

PMCID:: PMC4414354

Abstract Article PDF–2.8M

Select item 438453019.

A map of directional genetic interactions in a metazoan cell

Bernd Fischer, Thomas Sandmann, Thomas Horn, Maximilian Billmann, Varun Chaudhary, Wolfgang Huber, Michael Boutros

eLife. 2015; 4: e05464. Published online 2015 Mar 6. doi: 10.7554/eLife.05464

PMCID:: PMC4384530

Abstract Article PDF–9.2M

Select item 438152320.

A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development

Claus Schertel, Monica Albarca, Claudia Rockel-Bauer, Nicholas W. Kelley, Johannes Bischof, Korneel Hens, Erik van Nimwegen, Konrad Basler, Bart Deplancke

Genome Res. 2015 Apr; 25(4): 514–523. doi: 10.1101/gr.181305.114

PMCID:: PMC4381523

Abstract Article PDF–700K

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