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Items: 1 to 20 of 278

1.
Usp14 down-regulation corrects sleep and circadian dysfunction of a Drosophila model of Parkinson’s disease
Mariavittoria Favaro, Sofia Mauri, Greta Bernardo, Mauro A. Zordan, Gabriella M. Mazzotta, Elena Ziviani
Front Neurosci. 2024; 18: 1410139. Published online 2024 Aug 5. doi: 10.3389/fnins.2024.1410139
PMCID:
PMC11330830
AbstractArticlePDF–7.6M
2.
CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca2+ homeostasis
Aya Ikeda, Hongrui Meng, Daisuke Taniguchi, Muneyo Mio, Manabu Funayama, Kenya Nishioka, Mari Yoshida, Yuanzhe Li, Hiroyo Yoshino, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Yohei Okubo, Takashi Sakurai, Taku Amo, Ikuko Aiba, Yufuko Saito, Yuko Saito, Shigeo Murayama, Naoki Atsuta, Ryoichi Nakamura, Genki Tohnai, Yuishin Izumi, Mitsuya Morita, Asako Tamura, Osamu Kano, Masaya Oda, Satoshi Kuwabara, Toru Yamashita, Jun Sone, Ryuji Kaji, Gen Sobue, Yuzuru Imai, Nobutaka Hattori
PNAS Nexus. 2024 Aug; 3(8): pgae319. Published online 2024 Jul 30. doi: 10.1093/pnasnexus/pgae319
PMCID:
PMC11316225
AbstractArticlePDF–1.4M
3.
Dysfunction of Mitochondrial Dynamics Induces Endocytosis Defect and Cell Damage in Drosophila Nephrocytes
Jun-yi Zhu, Jianli Duan, Joyce van de Leemput, Zhe Han
Cells. 2024 Aug; 13(15): 1253. Published online 2024 Jul 25. doi: 10.3390/cells13151253
PMCID:
PMC11312102
AbstractArticlePDF–9.1M
4.
Modeling neurodegenerative and neurodevelopmental disorders in the Drosophila mushroom body
Aaron Stahl, Seth M. Tomchik
Learn Mem. 2024 May; 31(5): a053816. Published online 2024 May. doi: 10.1101/lm.053816.123
PMCID:
PMC11199955
AbstractArticlePDF–937K
5.
Senescent glia link mitochondrial dysfunction and lipid accumulation
China N. Byrns, Alexandra E. Perlegos, Karl N. Miller, Zhecheng Jin, Faith R. Carranza, Palak Manchandra, Connor H. Beveridge, Caitlin E. Randolph, V. Sai Chaluvadi, Shirley L. Zhang, Ananth R. Srinivasan, F. C. Bennett, Amita Sehgal, Peter D. Adams, Gaurav Chopra, Nancy M. Bonini
Nature. 2024; 630(8016): 475–483. Published online 2024 Jun 5. doi: 10.1038/s41586-024-07516-8
Correction in:
Nature. 2024; 632(8026): E8.
PMCID:
PMC11168935
AbstractArticlePDF–17M
6.
Restricting bioenergetic efficiency enhances longevity and mitochondrial redox capacity in Drosophila melanogaster
Analisa L. Taylor, Olga Dubuisson, Pritika Pandey, Elizabeth R. M. Zunica, Bolormaa Vandanmagsar, Wagner S. Dantas, Alyssa Johnson, Christopher L. Axelrod, John P. Kirwan
Aging Cell. 2024 May; 23(5): e14107. Published online 2024 Feb 11. doi: 10.1111/acel.14107
PMCID:
PMC11113268
AbstractArticlePDF–655K
7.
Promoting mitochondrial dynamics by inhibiting the PINK1–PRKN pathway to relieve diabetic nephropathy
Jun-yi Zhu, Joyce van de Leemput, Zhe Han
Dis Model Mech. 2024 Apr 1; 17(4): dmm050471. Published online 2024 May 1. doi: 10.1242/dmm.050471
PMCID:
PMC11095637
AbstractArticle
8.
Fly for ALS: Drosophila modeling on the route to amyotrophic lateral sclerosis modifiers
Francesco Liguori, Susanna Amadio, Cinzia Volonté
Cell Mol Life Sci. 2021 Sep; 78(17-18): 6143–6160. Published online 2021 Jul 28. doi: 10.1007/s00018-021-03905-8
PMCID:
PMC11072332
AbstractArticlePDF–1.2M
9.
Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila
Jenny Zhe Liao, Hyung-lok Chung, Claire Shih, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C. Marcogliese, Katherine Sew, Hugo J. Bellen, Esther M. Verheyen
Nat Commun. 2024; 15: 3326. Published online 2024 Apr 18. doi: 10.1038/s41467-024-47623-8
PMCID:
PMC11026413
AbstractArticlePDF–18M
10.
Mitochondrial Differentiation during Spermatogenesis: Lessons from Drosophila melanogaster
Viktor Vedelek, Ferenc Jankovics, János Zádori, Rita Sinka
Int J Mol Sci. 2024 Apr; 25(7): 3980. Published online 2024 Apr 3. doi: 10.3390/ijms25073980
PMCID:
PMC11012351
AbstractArticlePDF–7.4M
11.
A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis
Paula R. Haynes, Elana S. Pyfrom, Yongjun Li, Carly Stein, Vishnu Anand Cuddapah, Jack A. Jacobs, Zhifeng Yue, Amita Sehgal
Nat Neurosci. 2024; 27(4): 666–678. Published online 2024 Feb 15. doi: 10.1038/s41593-023-01568-1
PMCID:
PMC11001586
AbstractArticlePDF–5.6M
12.
Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis
Ji Geng, Shuangxi Li, Yu Li, Zhihao Wu, Sunil Bhurtel, Suman Rimal, Danish Khan, Rani Ohja, Onn Brandman, Bingwei Lu
Nat Commun. 2024; 15: 1637. Published online 2024 Feb 22. doi: 10.1038/s41467-024-45525-3
PMCID:
PMC10883933
AbstractArticlePDF–3.9M
13.
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies
Elena Marchesan, Alice Nardin, Sofia Mauri, Greta Bernardo, Vivek Chander, Simone Di Paola, Monica Chinellato, Sophia von Stockum, Joy Chakraborty, Stephanie Herkenne, Valentina Basso, Emilie Schrepfer, Oriano Marin, Laura Cendron, Diego L. Medina, Luca Scorrano, Elena Ziviani
Cell Death Differ. 2024 Feb; 31(2): 217–238. Published online 2024 Jan 18. doi: 10.1038/s41418-023-01251-9
PMCID:
PMC10850161
AbstractArticlePDF–19M
14.
mtDNA extramitochondrial replication mediates mitochondrial defect effects
Zhaoliang Shan, Shengnan Li, Yuxue Gao, Chunhua Jian, Xiuxiu Ti, Hui Zuo, Ying Wang, Guochun Zhao, Yan Wang, Qing Zhang
iScience. 2024 Feb 16; 27(2): 108970. Published online 2024 Jan 19. doi: 10.1016/j.isci.2024.108970
PMCID:
PMC10844862
AbstractArticlePDF–8.0M
15.
Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
Aitor Martinez, Alvaro Sanchez-Martinez, Jake T. Pickering, Madeleine J. Twyning, Ana Terriente-Felix, Po-Lin Chen, Chun-Hong Chen, Alexander J. Whitworth
Mol Neurodegener. 2024; 19: 12. Published online 2024 Jan 25. doi: 10.1186/s13024-024-00701-3
PMCID:
PMC10811860
AbstractArticlePDF–13M
16.
Mass isolation of staged Drosophila pupal intestines for analysis of protein ubiquitylation
Ruoxi Wang, Panagiotis D. Velentzas, Eric H. Baehrecke
STAR Protoc. 2023 Dec 15; 4(4): 102713. Published online 2023 Nov 11. doi: 10.1016/j.xpro.2023.102713
PMCID:
PMC10682243
AbstractArticlePDF–4.2M
17.
Protein modification regulated autophagy in Bombyx mori and Drosophila melanogaster
Wenmei Wu, Luobin Lin, Yuntao Zhao, Huaqin Li, Rongxin Zhang
Front Physiol. 2023; 14: 1281555. Published online 2023 Nov 9. doi: 10.3389/fphys.2023.1281555
PMCID:
PMC10665574
AbstractArticlePDF–1.1M
18.
Structure and molecular basis of spermatid elongation in the Drosophila testis
Qiuru Huang, Xia Chen, Hao Yu, Li Ji, Yi Shi, Xinmeng Cheng, Hao Chen, Jun Yu
Open Biol. 2023 Nov; 13(11): 230136. Published online November 8, 2023. doi: 10.1098/rsob.230136
PMCID:
PMC10645079
AbstractArticlePDF–1.0M
19.
Senolytic and senomorphic secondary metabolites as therapeutic agents in Drosophila melanogaster models of Parkinson’s disease
Sean J. Miller, Rayyan Y. Darji, Sami Walaieh, Jhemerial A. Lewis, Robert Logan
Front Neurol. 2023; 14: 1271941. Published online 2023 Sep 28. doi: 10.3389/fneur.2023.1271941
PMCID:
PMC10568035
AbstractArticlePDF–2.2M
20.
PINK1, Keap1 and Rtnl1 regulate selective clearance of endoplasmic reticulum during development
Ruoxi Wang, Tina M. Fortier, Fei Chai, Guangyan Miao, James L. Shen, Lucas J. Restrepo, Jeromy J. DiGiacomo, Panagiotis D. Velentzas, Eric H. Baehrecke
Cell. Author manuscript; available in PMC 2024 Sep 14.
Published in final edited form as: Cell. 2023 Sep 14; 186(19): 4172–4188.e18. Published online 2023 Aug 25. doi: 10.1016/j.cell.2023.08.008
PMCID:
PMC10530463
AbstractArticlePDF–5.1M

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