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Select item 114472561.

Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer

Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y

PMCID:: PMC11447256

Abstract Article PDF–2.8M

Select item 111381022.

EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis

Annika Glotzbach, Katharina Rohlf, Anastasia Gonscharow, Simon Lüke, Özlem Demirci, Brigitte Begher-Tibbe, Nina Overbeck, Jörg Reinders, Cristina Cadenas, Jan G. Hengstler, Karolina Edlund, Rosemarie Marchan

Breast Cancer Res. 2024; 26: 87. Published online 2024 May 30. doi: 10.1186/s13058-024-01849-y

PMCID:: PMC11138102

Abstract Article PDF–2.2M

Select item 103927323.

Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1

Ying Liu, Hanwen Zhang, Yiwei Liu, Siyue Zhang, Peng Su, Lijuan Wang, Yaming Li, Yiran Liang, Xiaolong Wang, Weijing Zhao, Bing Chen, Dan Luo, Ning Zhang, Qifeng Yang

Autophagy. 2023; 19(9): 2443–2463. Published online 2023 Mar 1. doi: 10.1080/15548627.2023.2182482

PMCID:: PMC10392732

Abstract Article PDF–10M

Select item 98540784.

Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth

Magdalena Keller, Katharina Rohlf, Annika Glotzbach, Gregor Leonhardt, Simon Lüke, Katharina Derksen, Özlem Demirci, Defne Göçener, Mohammad AlWahsh, Jörg Lambert, Cecilia Lindskog, Marcus Schmidt, Walburgis Brenner, Matthias Baumann, Eldar Zent, Mia-Lisa Zischinsky, Birte Hellwig, Katrin Madjar, Jörg Rahnenführer, Nina Overbeck, Jörg Reinders, Cristina Cadenas, Jan G. Hengstler, Karolina Edlund, Rosemarie Marchan

J Exp Clin Cancer Res. 2023; 42: 25. Published online 2023 Jan 20. doi: 10.1186/s13046-022-02578-w

PMCID:: PMC9854078

Abstract Article PDF–4.3M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81343136.

Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle

Megan A. Palmer, Eleanor Smart, Iain S. Haslam

Histochem Cell Biol. 2021; 155(5): 529–545. Published online 2021 Jan 6. doi: 10.1007/s00418-020-01957-8

PMCID:: PMC8134313

Abstract Article PDF–4.2M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 49101508.

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ

Kyeong Won Lee, Soo Heon Kwak, Young Do Koo, Yun-Kyung Cho, Hak Mo Lee, Hye Seung Jung, Young Min Cho, Young Joo Park, Sung Soo Chung, Kyong Soo Park

Exp Mol Med. 2016 May; 48(5): e234. Published online 2016 May 20. doi: 10.1038/emm.2016.31

PMCID:: PMC4910150

Abstract Article PDF–1.1M

Select item 45945379.

EDI3 links choline metabolism to integrin expression, cell adhesion and spreading

Michaela S Lesjak, Rosemarie Marchan, Joanna D Stewart, Eugen Rempel, Jörg Rahnenführer, Jan G Hengstler

Cell Adh Migr. 2014 Sep-Oct; 8(5): 499–508. Published online 2014 Oct 31. doi: 10.4161/cam.29284

PMCID:: PMC4594537

Abstract Article PDF–779K

Select item 402246310.

Mutations in the Cholesterol Transporter Gene ABCA5 Are Associated with Excessive Hair Overgrowth

Gina M. DeStefano, Mazen Kurban, Kwame Anyane-Yeboa, Claudia Dall'Armi, Gilbert Di Paolo, Heather Feenstra, Nanette Silverberg, Luis Rohena, Larissa D. López-Cepeda, Vaidehi Jobanputra, Katherine A. Fantauzzo, Maija Kiuru, Marija Tadin-Strapps, Antonio Sobrino, Anna Vitebsky, Dorothy Warburton, Brynn Levy, Julio C. Salas-Alanis, Angela M. Christiano

PLoS Genet. 2014 May; 10(5): e1004333. Published online 2014 May 15. doi: 10.1371/journal.pgen.1004333

PMCID:: PMC4022463

Abstract Article PDF–6.7M

Select item 341170011.

Identification of CBX3 and ABCA5 as Putative Biomarkers for Tumor Stem Cells in Osteosarcoma

Vaibhav Saini, Curtis D. Hose, Anne Monks, Kunio Nagashima, Bingnan Han, Dianne L. Newton, Angelena Millione, Jalpa Shah, Melinda G. Hollingshead, Karen M. Hite, Mark W. Burkett, Rene M. Delosh, Thomas E. Silvers, Dominic A. Scudiero, Robert H. Shoemaker

PLoS One. 2012; 7(8): e41401. Published online 2012 Aug 3. doi: 10.1371/journal.pone.0041401

Correction in:: PLoS One. 2012; 7(11): 10.1371/annotation/8c74aaee-897d-4682-b62d-d95a3506c210.

PMCID:: PMC3411700

Abstract Article PDF–1.5M

Select item 336140912.

Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis

Joanna D. Stewart, Rosemarie Marchan, Michaela S. Lesjak, Joerg Lambert, Roland Hergenroeder, James K. Ellis, Chung-Ho Lau, Hector C. Keun, Gerd Schmitz, Juergen Schiller, Mandy Eibisch, Christian Hedberg, Herbert Waldmann, Ekkehart Lausch, Berno Tanner, Jalid Sehouli, Jens Sagemueller, Hagen Staude, Eric Steiner, Jan G. Hengstler

Proc Natl Acad Sci U S A. 2012 May 22; 109(21): 8155–8160. Published online 2012 May 8. doi: 10.1073/pnas.1117654109

PMCID:: PMC3361409

Abstract Article PDF–618K

Select item 331091113.

Global landscape of HIV–human protein complexes

Stefanie Jäger, Peter Cimermancic, Natali Gulbahce, Jeffrey R. Johnson, Kathryn E. McGovern, Starlynn C. Clarke, Michael Shales, Gaelle Mercenne, Lars Pache, Kathy Li, Hilda Hernandez, Gwendolyn M. Jang, Shoshannah L. Roth, Eyal Akiva, John Marlett, Melanie Stephens, Ivan D’Orso, Jason Fernandes, Marie Fahey, Cathal Mahon, Anthony J. O’Donoghue, Aleksandar Todorovic, John H. Morris, David A. Maltby, Tom Alber, Gerard Cagney, Frederic D. Bushman, John A. Young, Sumit K. Chanda, Wesley I. Sundquist, Tanja Kortemme, Ryan D. Hernandez, Charles S. Craik, Alma Burlingame, Andrej Sali, Alan D. Frankel, Nevan J. Krogan

Nature. Author manuscript; available in PMC 2013 Jan 19.

Published in final edited form as: Nature. 2011 Dec 21; 481(7381): 365–370. Published online 2011 Dec 21. doi: 10.1038/nature10719

PMCID:: PMC3310911

Abstract Article PDF–1.8M

Select item 330976214.

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

Trygve E. Bakken, J. Cooper Roddey, Srdjan Djurovic, Natacha Akshoomoff, David G. Amaral, Cinnamon S. Bloss, B. J. Casey, Linda Chang, Thomas M. Ernst, Jeffrey R. Gruen, Terry L. Jernigan, Walter E. Kaufmann, Tal Kenet, David N. Kennedy, Joshua M. Kuperman, Sarah S. Murray, Elizabeth R. Sowell, Lars M. Rimol, Morten Mattingsdal, Ingrid Melle, Ingrid Agartz, Ole A. Andreassen, Nicholas J. Schork, Anders M. Dale, for the Alzheimer's Disease Neuroimaging Initiative, Pediatric Imaging, Neurocognition, and Genetics Study

Proc Natl Acad Sci U S A. 2012 Mar 6; 109(10): 3985–3990. Published online 2012 Feb 16. doi: 10.1073/pnas.1105829109

PMCID:: PMC3309762

Abstract Article PDF–421K

Select item 326170815.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 322018616.

Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes

Lin T. Guey, Montserrat García-Closas, Cristiane Murta-Nascimento, Josep Lloreta, Laia Palencia, Manolis Kogevinas, Nathaniel Rothman, Gemma Vellalta, Malu Calle, Gaëlle Marenne, Adonina Tardón, Alfredo Carrato, Reina García-Closas, Consol Serra, Debra T Silverman, Stephen Chanock, Francisco X. Real, Núria Malats

Eur Urol. Author manuscript; available in PMC 2011 Nov 18.

Published in final edited form as: Eur Urol. 2010 Feb; 57(2): 283–292. Published online 2009 Aug 12. doi: 10.1016/j.eururo.2009.08.001

PMCID:: PMC3220186

Abstract Article PDF–595K

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 293463318.

A Novel Glycerophosphodiester Phosphodiesterase, GDE5, Controls Skeletal Muscle Development via a Non-enzymatic Mechanism

Yuri Okazaki, Noriyasu Ohshima, Ikumi Yoshizawa, Yasutomi Kamei, Stefania Mariggiò, Keiko Okamoto, Masahiro Maeda, Yoshihito Nogusa, Yuichiro Fujioka, Takashi Izumi, Yoshihiro Ogawa, Yoshitsugu Shiro, Masanobu Wada, Norihisa Kato, Daniela Corda, Noriyuki Yanaka

J Biol Chem. 2010 Sep 3; 285(36): 27652–27663. Published online 2010 Jun 24. doi: 10.1074/jbc.M110.106708

PMCID:: PMC2934633

Abstract Article PDF–1.8M

Select item 278379919.

PTEN IDENTIFIED AS IMPORTANT RISK FACTOR OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

H Dean Hosgood, III, Idan Menashe, Xingzhou He, Stephen Chanock, Qing Lan

Respir Med. Author manuscript; available in PMC 2010 Dec 1.

Published in final edited form as: Respir Med. 2009 Dec; 103(12): 1866–1870. Published online 2009 Jul 21. doi: 10.1016/j.rmed.2009.06.016

PMCID:: PMC2783799

Abstract Article PDF–315K

Select item 272285720.

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway

H.Dean Hosgood, III, Idan Menashe, Min Shen, Meredith Yeager, Jeff Yuenger, Preetha Rajaraman, Xingzhou He, Nilanjan Chatterjee, Neil E. Caporaso, Yong Zhu, Stephen J. Chanock, Tongzhang Zheng, Qing Lan

Carcinogenesis. 2008 Oct; 29(10): 1938–1943. Published online 2008 Aug 1. doi: 10.1093/carcin/bgn178

PMCID:: PMC2722857

Abstract Article PDF–181K

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