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Select item 106224161.

Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy

Yuhao Min, Xue Wang, Özkan İş, Tulsi A. Patel, Junli Gao, Joseph S. Reddy, Zachary S. Quicksall, Thuy Nguyen, Shu Lin, Frederick Q. Tutor-New, Jessica L. Chalk, Adriana O. Mitchell, Julia E. Crook, Peter T. Nelson, Linda J. Van Eldik, Todd E. Golde, Minerva M. Carrasquillo, Dennis W. Dickson, Ke Zhang, Mariet Allen, Nilüfer Ertekin-Taner

Nat Commun. 2023; 14: 6801. Published online 2023 Nov 2. doi: 10.1038/s41467-023-42626-3

PMCID:: PMC10622416

Abstract Article PDF–2.8M

Select item 105847552.

Insights into human kidney function from the study of Drosophila

Sybille Koehler, Tobias B. Huber

Pediatr Nephrol. 2023; 38(12): 3875–3887. Published online 2023 May 12. doi: 10.1007/s00467-023-05996-w

PMCID:: PMC10584755

Abstract Article PDF–1.2M

Select item 102992783.

The Landscape of the DNA Transposons in the Genome of the Horezu_LaPeri Strain of Drosophila melanogaster

Alexandru Marian Bologa, Ileana Stoica, Nicoleta Denisa Constantin, Alexandru Al. Ecovoiu

Insects. 2023 Jun; 14(6): 494. Published online 2023 May 25. doi: 10.3390/insects14060494

PMCID:: PMC10299278

Abstract Article PDF–3.2M

Select item 102380944.

Shared enhancer gene regulatory networks between wound and oncogenic programs

Swann Floc'hlay, Ramya Balaji, Dimitrije Stanković, Valerie M Christiaens, Carmen Bravo González-Blas, Seppe De Winter, Gert J Hulselmans, Maxime De Waegeneer, Xiaojiang Quan, Duygu Koldere, Mardelle Atkins, Georg Halder, Mirka Uhlirova, Anne-Kathrin Classen, Stein Aerts

eLife. 2023; 12: e81173. Published online 2023 May 3. doi: 10.7554/eLife.81173

PMCID:: PMC10238094

Abstract Article PDF–8.8M

Select item 102126045.

Developmental regulation of epithelial cell cuboidal-to-squamous transition in Drosophila follicle cells

Dongyu Jia, Allison Jevitt, Yi-Chun Huang, Belen Ramos, Wu-Min Deng

Dev Biol. Author manuscript; available in PMC 2023 May 25.

Published in final edited form as: Dev Biol. 2022 Nov; 491: 113–125. Published online 2022 Sep 12. doi: 10.1016/j.ydbio.2022.09.001

PMCID:: PMC10212604

Abstract Article PDF–2.7M

Select item 88989026.

Using Drosophila Nephrocytes to Understand the Formation and Maintenance of the Podocyte Slit Diaphragm

Joyce van de Leemput, Pei Wen, Zhe Han

Front Cell Dev Biol. 2022; 10: 837828. Published online 2022 Feb 21. doi: 10.3389/fcell.2022.837828

PMCID:: PMC8898902

Abstract Article PDF–1018K

Select item 84867857.

Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP–PKA signaling

Pedro Machado Almeida, Blanca Lago Solis, Luca Stickley, Alexis Feidler, Emi Nagoshi

Nat Commun. 2021; 12: 5758. Published online 2021 Oct 1. doi: 10.1038/s41467-021-26031-2

PMCID:: PMC8486785

Abstract Article PDF–3.2M

Select item 69615788.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 66756089.

Gene expression atlas of a developing tissue by single cell expression correlation analysis

Josephine Bageritz, Philipp Willnow, Erica Valentini, Svenja Leible, Michael Boutros, Aurelio A. Teleman

Nat Methods. Author manuscript; available in PMC 2020 Jan 29.

Published in final edited form as: Nat Methods. 2019 Jun 17; 16(8): 750–756. Published online 2019 Jul 29. doi: 10.1038/s41592-019-0492-x

PMCID:: PMC6675608

Abstract Article PDF–1.6M

Select item 607479210.

A Drosophila model system to assess the function of human monogenic podocyte mutations that cause nephrotic syndrome

Yulong Fu, Jun-yi Zhu, Adam Richman, Zhanzheng Zhao, Fujian Zhang, Patricio E. Ray, Zhe Han

Hum Mol Genet. 2017 Feb 15; 26(4): 768–780. Published online 2017 Feb 6. doi: 10.1093/hmg/ddw428

PMCID:: PMC6074792

Abstract Article PDF–1.4M

Select item 570780511.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900212.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 540772213.

Modeling Monogenic Human Nephrotic Syndrome in the Drosophila Garland Cell Nephrocyte

Tobias Hermle, Daniela A. Braun, Martin Helmstädter, Tobias B. Huber, Friedhelm Hildebrandt

J Am Soc Nephrol. 2017 May; 28(5): 1521–1533. Published online 2016 Dec 8. doi: 10.1681/ASN.2016050517

PMCID:: PMC5407722

Abstract Article

Select item 532507714.

Genome-wide measurement of spatial expression in patterning mutants of Drosophila melanogaster

Peter A. Combs, Michael B. Eisen

Version 1. F1000Res. 2017; 6: 41. Published online 2017 Jan 12. doi: 10.12688/f1000research.9720.1

PMCID:: PMC5325077

Abstract Article PDF–10M

Select item 493746615.

Buffering of Genetic Regulatory Networks in Drosophila melanogaster

Justin M. Fear, Luis G. León-Novelo, Alison M. Morse, Alison R. Gerken, Kjong Van Lehmann, John Tower, Sergey V. Nuzhdin, Lauren M. McIntyre

Genetics. 2016 Jul; 203(3): 1177–1190. Published online 2016 May 18. doi: 10.1534/genetics.116.188797

PMCID:: PMC4937466

Abstract Article PDF–2.4M

Select item 452833016.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832917.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 449775518.

KANK deficiency leads to podocyte dysfunction and nephrotic syndrome

Heon Yung Gee, Fujian Zhang, Shazia Ashraf, Stefan Kohl, Carolin E. Sadowski, Virginia Vega-Warner, Weibin Zhou, Svjetlana Lovric, Humphrey Fang, Margaret Nettleton, Jun-yi Zhu, Julia Hoefele, Lutz T. Weber, Ludmila Podracka, Andrej Boor, Henry Fehrenbach, Jeffrey W. Innis, Joseph Washburn, Shawn Levy, Richard P. Lifton, Edgar A. Otto, Zhe Han, Friedhelm Hildebrandt

J Clin Invest. 2015 Jun 1; 125(6): 2375–2384. Published online 2015 May 11. doi: 10.1172/JCI79504

PMCID:: PMC4497755

Abstract Article PDF–3.5M

Select item 439805019.

The Genetic Basis for Variation in Olfactory Behavior in Drosophila melanogaster

Gunjan H. Arya, Michael M. Magwire, Wen Huang, Yazmin L. Serrano-Negron, Trudy F.C. Mackay, Robert R.H. Anholt

Chem Senses. 2015 May; 40(4): 233–243. Published online 2015 Feb 15. doi: 10.1093/chemse/bjv001

PMCID:: PMC4398050

Abstract Article PDF–8.9M

Select item 435288720.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

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