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Items: 1 to 20 of 147

1.
Involvement of thioredoxin‐binding protein 2 in the antitumor activity of CD437
Saori Matsuoka, Hiroyuki Tsuchiya, Tomohiko Sakabe, Yumi Watanabe, Yoshiko Hoshikawa, Akihiro Kurimasa, Hiroaki Itamochi, Tasuku Harada, Naoki Terakawa, Hiroshi Masutani, Junji Yodoi, Goshi Shiota
Cancer Sci. 2008 Dec; 99(12): 2485–2490. Published online 2008 Nov 19. doi: 10.1111/j.1349-7006.2008.00979.x
PMCID:
PMC11159347
AbstractArticlePDF–237K
2.
Apoptosis signal-regulating kinase-1 regulates thrombin-induced endothelial permeability
Hemant Giri, Amit K. Srivastava, Ulhas P. Naik
Vascul Pharmacol. Author manuscript; available in PMC 2023 Jun 18.
Published in final edited form as: Vascul Pharmacol. 2022 Aug; 145: 107088. Published online 2022 Jul 4. doi: 10.1016/j.vph.2022.107088
PMCID:
PMC10276900
AbstractArticlePDF–2.0M
3.
Ubiquitin-specific protease 29 attenuates hepatic ischemia-reperfusion injury by mediating TGF-β-activated kinase 1 deubiquitination
Zhongbao Chen, Fengjiao Hu, Yalong Zhang, Long Zhang, Tianyu Wang, Chenyang Kong, Haochong Hu, Jiayu Guo, Qi Chen, Bo Yu, Yiting Liu, Jilin Zou, Jiangqiao Zhou, Tao Qiu
Front Immunol. 2023; 14: 1167667. Published online 2023 May 26. doi: 10.3389/fimmu.2023.1167667
PMCID:
PMC10250730
AbstractArticlePDF–10M
4.
Phosphoproteomics identifies pathways underlying the role of receptor‐interaction protein kinase 3 in alcohol‐associated liver disease and uncovers apoptosis signal‐regulating kinase 1 as a target
Vaibhav Singh, Emily Huang, Vai Pathak, Belinda B. Willard, Daniela S. Allende, Laura E. Nagy
Hepatol Commun. 2022 Aug; 6(8): 2022–2041. Published online 2022 Apr 19. doi: 10.1002/hep4.1956
PMCID:
PMC9315126
AbstractArticlePDF–11M
5.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
6.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
7.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
8.
Structural Insights Support Targeting ASK1 Kinase for Therapeutic Interventions
Veronika Obsilova, Karolina Honzejkova, Tomas Obsil
Int J Mol Sci. 2021 Dec; 22(24): 13395. Published online 2021 Dec 13. doi: 10.3390/ijms222413395
PMCID:
PMC8705584
AbstractArticlePDF–1.8M
9.
MEKK5 Interacts with and Negatively Regulates the E3 Ubiquitin Ligase NEDD4 for Mediating Lung Cancer Cell Migration
Aiqin Sun, Jun Zhu, Song Xia, Yanling Li, Tiantian Wu, Genbao Shao, Wannian Yang, Qiong Lin
Life (Basel) 2021 Nov; 11(11): 1153. Published online 2021 Oct 29. doi: 10.3390/life11111153
PMCID:
PMC8620495
AbstractArticlePDF–2.4M
10.
Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibition Reduces Endothelial Cytokine Production without Improving Permeability after Toll-like Receptor 4 (TLR4) Challenge
Michael R. Miller, Stephen R. Koch, Hyehun Choi, Fred S. Lamb, Ryan J. Stark
Transl Res. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Transl Res. 2021 Sep; 235: 115–128. Published online 2021 Apr 20. doi: 10.1016/j.trsl.2021.04.001
PMCID:
PMC8328918
AbstractArticlePDF–2.0M
11.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
12.
Lifespan extension conferred by mitogen-activated protein kinase kinase kinase 5 (MAP3K5) longevity-associated gene variation is confined to at-risk men with a cardiometabolic disease
Brian J. Morris, Randi Chen, Timothy A. Donlon, Kamal H. Masaki, D. Craig Willcox, Richard C. Allsopp, Bradley J. Willcox
Aging (Albany NY) 2021 Mar 31; 13(6): 7953–7974. Published online 2021 Mar 19. doi: 10.18632/aging.202844
PMCID:
PMC8034933
AbstractArticlePDF–1.3M
13.
Mechanisms of Trx2/ASK1-Mediated Mitochondrial Injury in Pemphigus Vulgaris
Bin Wei, Fenghe Li
Biomed Res Int. 2021; 2021: 2471518. Published online 2021 Feb 23. doi: 10.1155/2021/2471518
PMCID:
PMC7946479
AbstractArticlePDF–2.9M
14.
ASK1 Enhances Angiotensin II-Induced Liver Fibrosis In Vitro by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes
Pei-pei Fang, Chen-wei Pan, Wei Lin, Jie Li, Shan-shan Huang, Guang-yao Zhou, Wen-jun Du, Qiang Li
Mediators Inflamm. 2020; 2020: 8183713. Published online 2020 Nov 7. doi: 10.1155/2020/8183713
PMCID:
PMC7669360
AbstractArticlePDF–3.5M
15.
Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation
M Won, KA Park, HS Byun, K-C Sohn, Y-R Kim, J Jeon, JH Hong, J Park, JH Seok, JM Kim, W-H Yoon, I-S Jang, HM Shen, ZG Liu, GM Hur
Cell Death Differ. Author manuscript; available in PMC 2020 Jul 28.
Published in final edited form as: Cell Death Differ. 2010 Dec; 17(12): 1830–1841. Published online 2010 May 7. doi: 10.1038/cdd.2010.47
PMCID:
PMC7386326
AbstractArticlePDF–4.3M
16.
ARRB1 ameliorates liver ischaemia/reperfusion injury via antagonizing TRAF6‐mediated Lysine 6‐linked polyubiquitination of ASK1 in hepatocytes
Xiaoliang Xu, Zechuan Zhang, Yijun Lu, Qikai Sun, Yang Liu, Qiaoyu Liu, Wenfang Tian, Yin Yin, Hailong Yu, Beicheng Sun
J Cell Mol Med. 2020 Jul; 24(14): 7814–7828. Published online 2020 May 23. doi: 10.1111/jcmm.15412
PMCID:
PMC7348167
AbstractArticlePDF–2.5M
17.
Large tumor suppressor 2, LATS2, activates JNK in a kinase-independent mechanism through ASK1
Lauren Rusnak, Cong Tang, Qi Qi, Xiulei Mo, Haian Fu
J Mol Cell Biol. 2018 Dec; 10(6): 549–558. Published online 2018 Nov 29. doi: 10.1093/jmcb/mjy061
PMCID:
PMC7191879
AbstractArticlePDF–544K
18.
Calcium-induced dissociation of CIB1 from ASK1 regulates agonist-induced activation of the p38 MAPK pathway in platelets
Pravin Patel, Meghna U. Naik, Kalyan Golla, Noor F. Shaik, Ulhas P. Naik
Biochem J. Author manuscript; available in PMC 2020 Oct 15.
Published in final edited form as: Biochem J. 2019 Oct 15; 476(19): 2835–2850. doi: 10.1042/BCJ20190410
PMCID:
PMC7071732
AbstractArticlePDF–1.6M
19.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
20.
Liver ASK1 protects from non‐alcoholic fatty liver disease and fibrosis
Tenagne D Challa, Stephan Wueest, Fabrizio C Lucchini, Mara Dedual, Salvatore Modica, Marcela Borsigova, Christian Wolfrum, Matthias Blüher, Daniel Konrad
EMBO Mol Med. 2019 Oct; 11(10): e10124. Published online 2019 Jun 6. doi: 10.15252/emmm.201810124
PMCID:
PMC6783644
AbstractArticlePDF–1.7M

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