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Items: 1 to 20 of 21

1.
ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration
Jennifer Kosinski, Antonio Sechi, Johanna Hain, Sophia Villwock, Stefanie Anh Ha, Maximilian Hauschulz, Michael Rose, Florian Steib, Nadina Ortiz‐Brüchle, Lara Heij, Sanne L. Maas, Emiel P. C. van der Vorst, Thomas Knoesel, Annelore Altendorf‐Hofmann, Ronald Simon, Guido Sauter, Jan Bednarsch, Danny Jonigk, Edgar Dahl
Mol Oncol. 2024 Jun; 18(6): 1486–1509. Published online 2024 Feb 20. doi: 10.1002/1878-0261.13609
PMCID:
PMC11161730
AbstractArticlePDF–5.1M
2.
The ECM Modulator ITIH5 Affects Cell Adhesion, Motility and Chemotherapeutic Response of Basal/Squamous-Like (BASQ) Bladder Cancer Cells
Michael Rose, Erik Noetzel, Jennifer Kistermann, Julian Eschenbruch, Sandra Rushrush, Lin Gan, Ruth Knüchel, Nadine T. Gaisa, Edgar Dahl
Cells. 2021 May; 10(5): 1038. Published online 2021 Apr 28. doi: 10.3390/cells10051038
PMCID:
PMC8146567
AbstractArticlePDF–5.3M
3.
ITIH5, a p53-responsive gene, inhibits the growth and metastasis of melanoma cells by downregulating the transcriptional activity of KLF4
Jia Liu, Feng Cao, Xiaojie Li, Li Zhang, Zhengrong Liu, Xiaodong Li, Jingrong Lin, Chuanchun Han
Cell Death Dis. 2021 May; 12(5): 438. Published online 2021 May 2. doi: 10.1038/s41419-021-03707-7
PMCID:
PMC8089095
AbstractArticlePDF–4.8M
4.
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics
Alexandra Naba, Oliver M. T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes
J Proteome Res. Author manuscript; available in PMC 2021 Apr 27.
Published in final edited form as: J Proteome Res. 2017 Aug 4; 16(8): 3083–3091. Published online 2017 Jul 19. doi: 10.1021/acs.jproteome.7b00191
PMCID:
PMC8078728
AbstractArticlePDF–2.1M
5.
Suppression of pancreatic cancer liver metastasis by secretion-deficient ITIH5
Eric D. Young, Sharon J. Manley, Thomas C. Beadnell, Alexander E. Shearin, Ken Sasaki, Rosalyn Zimmerman, Evan Kauffman, Carolyn J. Vivian, Aishwarya Parasuram, Tomoo Iwakuma, Paul M. Grandgenett, Michael A. Hollingsworth, Maura O’Neil, Danny R. Welch
Br J Cancer. 2021 Jan 5; 124(1): 166–175. Published online 2020 Oct 7. doi: 10.1038/s41416-020-01093-z
PMCID:
PMC7782545
AbstractArticlePDF–3.3M
6.
Genome-wide in vivo RNAi screen identifies ITIH5 as a metastasis suppressor in pancreatic cancer
Ken Sasaki, Hiroshi Kurahara, Eric D. Young, Shoji Natsugoe, Asami Ijichi, Tomoo Iwakuma, Danny R Welch
Clin Exp Metastasis. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: Clin Exp Metastasis. 2017 Apr; 34(3-4): 229–239. Published online 2017 Mar 13. doi: 10.1007/s10585-017-9840-3
PMCID:
PMC5450640
AbstractArticlePDF–756K
7.
ITIH5 mediates epigenetic reprogramming of breast cancer cells
Michael Rose, Vera Kloten, Erik Noetzel, Lukas Gola, Josef Ehling, Timon Heide, Steffen K. Meurer, Aljona Gaiko-Shcherbak, Antonio S. Sechi, Sebastian Huth, Ralf Weiskirchen, Oliver Klaas, Wiebke Antonopoulos, Qiong Lin, Wolfgang Wagner, Jürgen Veeck, Felix Gremse, Julia Steitz, Ruth Knüchel, Edgar Dahl
Mol Cancer. 2017; 16: 44. Published online 2017 Feb 23. doi: 10.1186/s12943-017-0610-2
PMCID:
PMC5322623
AbstractArticlePDF–7.6M
8.
Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-α-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor β1 (TGFβ1)-dependent Fibroblast to Myofibroblast Differentiation
John Martin, Adam Midgley, Soma Meran, Emma Woods, Timothy Bowen, Aled O. Phillips, Robert Steadman
J Biol Chem. 2016 Jun 24; 291(26): 13789–13801. Published online 2016 May 3. doi: 10.1074/jbc.M115.670521
PMCID:
PMC4919461
AbstractArticlePDF–2.8M
9.
Low expression of ITIH5 in adenocarcinoma of the lung is associated with unfavorable patients' outcome
Magnus Mathias Dötsch, Vera Kloten, Martin Schlensog, Timon Heide, Till Braunschweig, Jürgen Veeck, Iver Petersen, Ruth Knüchel, Edgar Dahl
Epigenetics. 2015 Oct; 10(10): 903–912. Published online 2015 Aug 7. doi: 10.1080/15592294.2015.1078049
PMCID:
PMC4844218
AbstractArticlePDF–1006K
10.
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver
Alexandra Naba, Karl R Clauser, Charles A Whittaker, Steven A Carr, Kenneth K Tanabe, Richard O Hynes
BMC Cancer. 2014; 14: 518. Published online 2014 Jul 18. doi: 10.1186/1471-2407-14-518
PMCID:
PMC4223627
AbstractArticlePDF–1.5M
11.
Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator phenotype
Vera Kloten, Michael Rose, Sophie Kaspar, Saskia von Stillfried, Ruth Knüchel, Edgar Dahl
Epigenetics. 2014 Sep 1; 9(9): 1290–1301. Published online 2014 Aug 4. doi: 10.4161/epi.32089
PMCID:
PMC4169021
AbstractArticlePDF–2.1M
12.
Charting the Landscape of Tandem BRCT Domain-Mediated Protein Interactions
Nicholas T. Woods, Rafael D. Mesquita, Michael Sweet, Marcelo A. Carvalho, Xueli Li, Yun Liu, Huey Nguyen, C. Eric Thomas, Edwin S. Iversen, Jr., Sylvia Marsillac, Rachel Karchin, John Koomen, Alvaro N.A. Monteiro
Sci Signal. Author manuscript; available in PMC 2014 Jun 20.
Published in final edited form as: Sci Signal. 2012; 5(242): rs6. Published online 2012 Sep 18. doi: 10.1126/scisignal.2002255
PMCID:
PMC4064718
AbstractArticlePDF–2.1M
13.
Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening
Vera Kloten, Birte Becker, Kirsten Winner, Michael G Schrauder, Peter A Fasching, Tobias Anzeneder, Jürgen Veeck, Arndt Hartmann, Ruth Knüchel, Edgar Dahl
Breast Cancer Res. 2013; 15(1): R4. Published online 2013 Jan 15. doi: 10.1186/bcr3375
PMCID:
PMC3672828
AbstractArticlePDF–687K
14.
Genome-Wide Pleiotropy of Osteoporosis-Related Phenotypes: The Framingham Study
David Karasik, Yi-Hsiang Hsu, Yanhua Zhou, L Adrienne Cupples, Douglas P Kiel, Serkalem Demissie
J Bone Miner Res. 2010 Jul; 25(7): 1555–1563. Published online 2010 Jan 29. doi: 10.1002/jbmr.38
PMCID:
PMC3153998
AbstractArticlePDF–158K
15.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
16.
Gene expression profiling associated with the progression to poorly differentiated thyroid carcinomas
J M Pita, A Banito, B M Cavaco, V Leite
Br J Cancer. 2009 Nov 17; 101(10): 1782–1791. Published online 2009 Oct 6. doi: 10.1038/sj.bjc.6605340
PMCID:
PMC2778548
AbstractArticlePDF–533K
17.
Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: A systematic expression analysis
Alexander Hamm, Juergen Veeck, Nuran Bektas, Peter J Wild, Arndt Hartmann, Uwe Heindrichs, Glen Kristiansen, Tamra Werbowetski-Ogilvie, Rolando Del Maestro, Ruth Knuechel, Edgar Dahl
BMC Cancer. 2008; 8: 25. Published online 2008 Jan 28. doi: 10.1186/1471-2407-8-25
PMCID:
PMC2268946
AbstractArticlePDF–1.0M
18.
A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease
Andrew Grupe, Yonghong Li, Charles Rowland, Petra Nowotny, Anthony L. Hinrichs, Scott Smemo, John S. K. Kauwe, Taylor J. Maxwell, Sara Cherny, Lisa Doil, Kristina Tacey, Ryan van Luchene, Amanda Myers, Fabienne Wavrant-De Vrièze, Mona Kaleem, Paul Hollingworth, Luke Jehu, Catherine Foy, Nicola Archer, Gillian Hamilton, Peter Holmans, Chris M. Morris, Joseph Catanese, John Sninsky, Thomas J. White, John Powell, John Hardy, Michael O’Donovan, Simon Lovestone, Lesley Jones, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate
Am J Hum Genet. 2006 Jan; 78(1): 78–88. Published online 2005 Nov 15. doi: 10.1086/498851
PMCID:
PMC1380225
AbstractArticlePDF–329K
19.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
20.
The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment
Hilary F. Clark, Austin L. Gurney, Evangeline Abaya, Kevin Baker, Daryl Baldwin, Jennifer Brush, Jian Chen, Bernard Chow, Clarissa Chui, Craig Crowley, Bridget Currell, Bethanne Deuel, Patrick Dowd, Dan Eaton, Jessica Foster, Christopher Grimaldi, Qimin Gu, Philip E. Hass, Sherry Heldens, Arthur Huang, Hok Seon Kim, Laura Klimowski, Yisheng Jin, Stephanie Johnson, James Lee, Lhney Lewis, Dongzhou Liao, Melanie Mark, Edward Robbie, Celina Sanchez, Jill Schoenfeld, Somasekar Seshagiri, Laura Simmons, Jennifer Singh, Victoria Smith, Jeremy Stinson, Alicia Vagts, Richard Vandlen, Colin Watanabe, David Wieand, Kathryn Woods, Ming-Hong Xie, Daniel Yansura, Sothy Yi, Guoying Yu, Jean Yuan, Min Zhang, Zemin Zhang, Audrey Goddard, William I. Wood, Paul Godowski
Genome Res. 2003 Oct; 13(10): 2265–2270. doi: 10.1101/gr.1293003
Correction in:
Genome Res. 2003 Dec; 13(12): 2759.
PMCID:
PMC403697
AbstractArticlePDF–120K

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