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Select item 111055861.

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Albert Lee, Stephanie L. Rayner, Serene S. L. Gwee, Alana De Luca, Hamideh Shahheydari, Vinod Sundaramoorthy, Audrey Ragagnin, Marco Morsch, Rowan Radford, Jasmin Galper, Sarah Freckleton, Bingyang Shi, Adam K. Walker, Emily K. Don, Nicholas J. Cole, Shu Yang, Kelly L. Williams, Justin J. Yerbury, Ian P. Blair, Julie D. Atkin, Mark P. Molloy, Roger S. Chung

Cell Mol Life Sci. 2018 Jan; 75(2): 335–354. Published online 2017 Aug 29. doi: 10.1007/s00018-017-2632-8

PMCID:: PMC11105586

Abstract Article PDF–1.8M

Select item 110396102.

Overexpression of cyclin F/CCNF as an independent prognostic factor for poor survival in clear cell renal cell carcinoma

Maciej Kwiatkowski, Adrian Krajewski, Justyna Durślewicz, Karolina Buchholz, Dariusz Grzanka, Maciej Gagat, Jan Zabrzyński, Anna Klimaszewska-Wiśniewska

Sci Rep. 2024; 14: 9280. Published online 2024 Apr 23. doi: 10.1038/s41598-024-59437-1

PMCID:: PMC11039610

Abstract Article PDF–5.3M

Select item 106654713.

ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation

Audrey M. G. Ragagnin, Vinod Sundaramoorthy, Fabiha Farzana, Shashi Gautam, Sayanthooran Saravanabavan, Zeinab Takalloo, Prachi Mehta, Dzung Do-Ha, Sonam Parakh, Sina Shadfar, Julie Hunter, Marta Vidal, Cyril J. Jagaraj, Mariana Brocardo, Anna Konopka, Shu Yang, Stephanie L. Rayner, Kelly L. Williams, Ian P. Blair, Roger S. Chung, Albert Lee, Lezanne Ooi, Julie D. Atkin

Sci Rep. 2023; 13: 20467. Published online 2023 Nov 22. doi: 10.1038/s41598-023-46802-9

PMCID:: PMC10665471

Abstract Article PDF–11M

Select item 106523314.

ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis

Natalie E Farrawell, Monique Bax, Luke McAlary, Jessie McKenna, Simon Maksour, Dzung Do-Ha, Stephanie L Rayner, Ian P Blair, Roger S Chung, Justin J Yerbury, Lezanne Ooi, Darren N Saunders

Hum Mol Genet. 2023 Jul 15; 32(14): 2386–2398. Published online 2023 May 23. doi: 10.1093/hmg/ddad063

PMCID:: PMC10652331

Abstract Article PDF–1.6M

Select item 104154465.

The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis

Jennilee M. Davidson, Sharlynn S. L. Wu, Stephanie L. Rayner, Flora Cheng, Kimberley Duncan, Carlo Russo, Michelle Newbery, Kunjie Ding, Natalie M. Scherer, Rachelle Balez, Alberto García-Redondo, Alberto Rábano, Livia Rosa-Fernandes, Lezanne Ooi, Kelly L. Williams, Marco Morsch, Ian P. Blair, Antonio Di Ieva, Shu Yang, Roger S. Chung, Albert Lee

Mol Neurobiol. 2023; 60(9): 5034–5054. Published online 2023 May 27. doi: 10.1007/s12035-023-03355-2

PMCID:: PMC10415446

Abstract Article PDF–4.2M

Select item 102248176.

Genetic and Phenotypic Spectrum of Amyotrophic Lateral Sclerosis Patients with CCNF Variants from a Large Chinese Cohort

Bi Zhao, Qirui Jiang, Junyu Lin, Qianqian Wei, Chunyu Li, Yanbing Hou, Bei Cao, Lingyu Zhang, Ruwei Ou, Kuncheng Liu, Tianmi Yang, Yi Xiao, Rui Huang, Huifang Shang

Mol Neurobiol. 2023; 60(7): 4150–4160. Published online 2023 May 12. doi: 10.1007/s12035-023-03380-1

PMCID:: PMC10224817

Abstract Article PDF–1.9M

Select item 101561757.

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman

Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035

Correction in:: Cell. 2023 May 25; 186(11): 2492.

PMCID:: PMC10156175

Abstract Article

Select item 100060928.

The Skp1-Cullin1-FBXO1 complex is a pleiotropic regulator required for the formation of gametes and motile forms in Plasmodium berghei

Ravish Rashpa, Natacha Klages, Domitille Schvartz, Carla Pasquarello, Mathieu Brochet

Nat Commun. 2023; 14: 1312. Published online 2023 Mar 10. doi: 10.1038/s41467-023-36999-8

PMCID:: PMC10006092

Abstract Article PDF–11M

Select item 96997509.

The deubiquitylase USP7 is a novel cyclin F-interacting protein and regulates cyclin F protein stability

Savitha S. Sharma, W. Jack Pledger, Paturu Kondaiah

Aging (Albany NY) 2022 Nov 15; 14(21): 8645–8660. Published online 2022 Nov 5. doi: 10.18632/aging.204372

PMCID:: PMC9699750

Abstract Article PDF–1.1M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 926085611.

FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability

Nikol Dibus, Vladimir Korinek, Lukas Cermak

Front Cell Dev Biol. 2022; 10: 929288. Published online 2022 Jun 23. doi: 10.3389/fcell.2022.929288

Correction in:: Front Cell Dev Biol. 2022; 10: 1000878.

PMCID:: PMC9260856

Abstract Article PDF–2.8M

Select item 834132712.

Increased expression of Cyclin F in liver cancer predicts poor prognosis: A study based on TCGA database

Yang Zelong, Yang Han, Guo Ting, Wang Yifei, He Kun, Hu Haoran, Chen Yong

Medicine (Baltimore) 2021 Aug 6; 100(31): e26623. Published online 2021 Aug 6. doi: 10.1097/MD.0000000000026623

PMCID:: PMC8341327

Abstract Article PDF–1.3M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 809348714.

Sirtuin 5 Is Regulated by the SCF^{Cyclin F} Ubiquitin Ligase and Is Involved in Cell Cycle Control

Christine A. Mills, Xianxi Wang, Dhaval P. Bhatt, Paul A. Grimsrud, Jacob Peter Matson, Debojyoti Lahiri, Daniel J. Burke, Jeanette Gowen Cook, Matthew D. Hirschey, Michael J. Emanuele

Mol Cell Biol. 2021 Feb; 41(2): e00269-20. Prepublished online 2020 Nov 9. Published online 2021 Jan 25. doi: 10.1128/MCB.00269-20

PMCID:: PMC8093487

Abstract Article PDF–4.3M

Select item 679201015.

Cyclin F‐dependent degradation of E2F7 is critical for DNA repair and G2‐phase progression

Ruixue Yuan, Qingwu Liu, Hendrika A Segeren, Laurensia Yuniati, Daniele Guardavaccaro, Robert J Lebbink, Bart Westendorp, Alain de Bruin

EMBO J. 2019 Oct 15; 38(20): e101430. Published online 2019 Sep 2. doi: 10.15252/embj.2018101430

PMCID:: PMC6792010

Abstract Article PDF–3.0M

Select item 658846616.

Cyclin F controls cell cycle transcriptional outputs by directing the degradation of the three activator E2Fs

Linda Clijsters, Claire Hoencamp, Jorg J. A. Calis, Antonio Marzio, Shanna M. Handgraaf, Maria C. Cuitino, Brad R. Rosenberg, Gustavo Leone, Michele Pagano

Mol Cell. Author manuscript; available in PMC 2020 Jun 20.

Published in final edited form as: Mol Cell. 2019 Jun 20; 74(6): 1264–1277.e7. Published online 2019 May 23. doi: 10.1016/j.molcel.2019.04.010

PMCID:: PMC6588466

Abstract Article PDF–2.7M

Select item 632887417.

Prognostic values of F-box members in breast cancer: an online database analysis and literature review

Xiaochen Wang, Tao Zhang, Shizhen Zhang, Jinlan Shan

Biosci Rep. 2019 Jan 31; 39(1): BSR20180949. Prepublished online 2018 Oct 19. Published online 2019 Jan 3. doi: 10.1042/BSR20180949

PMCID:: PMC6328874

Abstract Article PDF–819K

Select item 617269218.

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression

Ioanna Mavrommati, Roberta Faedda, Giovanni Galasso, Jie Li, Kamila Burdova, Roman Fischer, Benedikt M. Kessler, Zunamys I. Carrero, Daniele Guardavaccaro, Michele Pagano, Vincenzo D’Angiolella

Cell Rep. 2018 Sep 25; 24(13): 3404–3412. Published online 2018 Sep 25. doi: 10.1016/j.celrep.2018.08.076

PMCID:: PMC6172692

Abstract Article

Select item 605973619.

Potential role of cyclin F mRNA expression in the survival of skin melanoma patients: Comprehensive analysis of the pathways altered due to cyclin F upregulation

Maciej Gagat, Adrian Krajewski, Dariusz Grzanka, Alina Grzanka

Oncol Rep. 2018 Jul; 40(1): 123–144. Published online 2018 May 16. doi: 10.3892/or.2018.6435

PMCID:: PMC6059736

Abstract Article PDF–2.7M

Select item 571159520.

Composition and regulation of the cellular repertoire of SCF ubiquitin ligases

Justin M. Reitsma, Xing Liu, Kurt M. Reichermeier, Annie Moradian, Michael J. Sweredoski, Sonja Hess, Raymond J. Deshaies

Cell. Author manuscript; available in PMC 2018 Nov 30.

Published in final edited form as: Cell. 2017 Nov 30; 171(6): 1326–1339.e14. Published online 2017 Nov 2. doi: 10.1016/j.cell.2017.10.016

PMCID:: PMC5711595

Abstract Article PDF–2.4M

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