PMC Links for GEO Profiles (Select 13560575) - PMC

Select item 110324541.

IL-6/gp130 signaling in CD4⁺ T cells drives the pathogenesis of pulmonary hypertension

Tomohiko Ishibashi, Tadakatsu Inagaki, Makoto Okazawa, Akiko Yamagishi, Keiko Ohta-Ogo, Ryotaro Asano, Takeshi Masaki, Yui Kotani, Xin Ding, Tomomi Chikaishi-Kirino, Noriko Maedera, Manabu Shirai, Kinta Hatakeyama, Yoshiaki Kubota, Tadamitsu Kishimoto, Yoshikazu Nakaoka

Proc Natl Acad Sci U S A. 2024 Apr 16; 121(16): e2315123121. Published online 2024 Apr 11. doi: 10.1073/pnas.2315123121

PMCID:: PMC11032454

Abstract Article PDF–7.6M

Select item 70034502.

Activating the interleukin-6-Gp130-STAT3 pathway ameliorates ventricular electrical stability in myocardial infarction rats by modulating neurotransmitters in the paraventricular nucleus

Meng Gao, Dechun Yin, Jugang Chen, Xiufen Qu

BMC Cardiovasc Disord. 2020; 20: 60. Published online 2020 Feb 5. doi: 10.1186/s12872-020-01363-x

PMCID:: PMC7003450

Abstract Article PDF–1.4M

Select item 67419773.

Glycoprotein 130 Signaling Regulates Notch1Expression and Activation in the Self-Renewal of Mammalian Forebrain Neural Stem Cells

Andrew Chojnacki, Takuya Shimazaki, Christopher Gregg, Gerry Weinmaster, Samuel Weiss

J Neurosci. 2003 Mar 1; 23(5): 1730–1741. doi: 10.1523/JNEUROSCI.23-05-01730.2003

PMCID:: PMC6741977

Abstract Article PDF–1.0M

Select item 59198304.

Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension

Yuichi Tamura, Carole Phan, Ly Tu, Morane Le Hiress, Raphaël Thuillet, Etienne-Marie Jutant, Elie Fadel, Laurent Savale, Alice Huertas, Marc Humbert, Christophe Guignabert

J Clin Invest. 2018 May 1; 128(5): 1956–1970. Published online 2018 Apr 9. doi: 10.1172/JCI96462

PMCID:: PMC5919830

Abstract Article PDF–16M

Select item 47190505.

Pulmonary instillation of MWCNT increases lung permeability, decreases gp130 expression in the lungs, and initiates cardiovascular IL-6 transsignaling

Leslie C. Thompson, Nathan A. Holland, Ryan J. Snyder, Bin Luo, Daniel P. Becak, Jillian T. Odom, Benjamin S. Harrison, Jared M. Brown, Kymberly M. Gowdy, Christopher J. Wingard

Am J Physiol Lung Cell Mol Physiol. 2016 Jan 15; 310(2): L142–L154. Published online 2015 Nov 20. doi: 10.1152/ajplung.00384.2014

PMCID:: PMC4719050

Abstract Article

Select item 45192896.

Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat

Sylvie Bradesi, Iordanes Karagiannides, Kyriaki Bakirtzi, Swapna Mahurkar Joshi, Georgios Koukos, Dimitrios Iliopoulos, Charalabos Pothoulakis, Emeran A. Mayer

PLoS One. 2015; 10(7): e0130938. Published online 2015 Jul 29. doi: 10.1371/journal.pone.0130938

PMCID:: PMC4519289

Abstract Article PDF–2.9M

Select item 42077917.

The Inhibition of N-Glycosylation of Glycoprotein 130 Molecule Abolishes STAT3 Activation by IL-6 Family Cytokines in Cultured Cardiac Myocytes

Reo Matsuo, Hirofumi Morihara, Tomomi Mohri, Shiho Murasawa, Kana Takewaki, Hiroyuki Nakayama, Makiko Maeda, Yasushi Fujio

PLoS One. 2014; 9(10): e111097. Published online 2014 Oct 23. doi: 10.1371/journal.pone.0111097

Correction in:: PLoS One. 2015; 10(3): e0122930.

PMCID:: PMC4207791

Abstract Article PDF–1.5M

Select item 39136898.

Biochemical and functional analyses of gp130 mutants unveil JAK1 as a novel therapeutic target in human inflammatory hepatocellular adenoma

Karine Poussin, Camilla Pilati, Gabrielle Couchy, Julien Calderaro, Paulette Bioulac-Sage, Yannick Bacq, Valérie Paradis, Emmanuelle Leteurtre, Nathalie Sturm, Jeanne Ramos, Catherine Guettier, Armelle Bardier-Dupas, Anais Boulai, Dominique Wendum, Janick Selves, Tina Izard, Jean-Charles Nault, Jessica Zucman-Rossi

Oncoimmunology. 2013 Dec 1; 2(12): e27090. Published online 2014 Jan 3. doi: 10.4161/onci.27090

PMCID:: PMC3913689

Abstract Article PDF–771K

Select item 37735059.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 373206810.

SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway

Antonio Cittadini, Maria Gaia Monti, Guido Iaccarino, Maria Carmina Castiello, Alfonso Baldi, Eduardo Bossone, Salvatore Longobardi, Alberto Maria Marra, Valentina Petrillo, Lavinia Saldamarco, Matthew John During, Luigi Saccà, Gianluigi Condorelli

Cardiovasc Res. 2012 Dec 1; 96(3): 381–390. Published online 2012 Aug 8. doi: 10.1093/cvr/cvs261

PMCID:: PMC3732068

Abstract Article PDF–585K

Select item 350040811.

Rat Mcs1b is concordant to the genome wide association identified breast cancer risk locus at human 5q11.2 and Mier3 is a candidate cancer susceptibility gene

Aaron D. denDekker, Xin Xu, M. Derek Vaughn, Aaron H. Puckett, Louis L. Gardner, Courtney J. Lambring, Lucas Deschenes, David J. Samuelson

Cancer Res. Author manuscript; available in PMC 2013 Nov 15.

Published in final edited form as: Cancer Res. 2012 Nov 15; 72(22): 6002–6012. Published online 2012 Sep 19. doi: 10.1158/0008-5472.CAN-12-0748

PMCID:: PMC3500408

Abstract Article PDF–763K

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316396213.

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

Simon A. Jones, Jürgen Scheller, Stefan Rose-John

J Clin Invest. 2011 Sep 1; 121(9): 3375–3383. Published online 2011 Sep 1. doi: 10.1172/JCI57158

PMCID:: PMC3163962

Abstract Article PDF–460K

Select item 294503114.

Differential effects of locally and systemically administered soluble glycoprotein 130 on pain and inflammation in experimental arthritis

Michael K Boettger, Johannes Leuchtweis, Diana Kümmel, Mieczyslaw Gajda, Rolf Bräuer, Hans-Georg Schaible

Arthritis Res Ther. 2010; 12(4): R140. Published online 2010 Jul 13. doi: 10.1186/ar3079

PMCID:: PMC2945031

Abstract Article PDF–1.3M

Select item 278572215.

Preconditioning-induced protection of photoreceptors requires activation of the signal-transducing receptor gp130 in photoreceptors

Yumi Ueki, Yun-Zheng Le, Srinivas Chollangi, Werner Muller, John D. Ash

Proc Natl Acad Sci U S A. 2009 Dec 15; 106(50): 21389–21394. Published online 2009 Nov 30. doi: 10.1073/pnas.0906156106

PMCID:: PMC2785722

Abstract Article PDF–2.2M

Select item 233610716.

Role of IL-6 in Chronic Muscle Hyperalgesic Priming

Olayinka A. Dina, Paul G. Green, Jon D. Levine

Neuroscience. Author manuscript; available in PMC 2008 Apr 25.

Published in final edited form as: Neuroscience. 2008 Mar 18; 152(2): 521–525. Published online 2008 Jan 12. doi: 10.1016/j.neuroscience.2008.01.006

PMCID:: PMC2336107

Abstract Article PDF–288K

Select item 211868117.

Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man

Maren Luchtefeld, Heribert Schunkert, Monika Stoll, Tina Selle, Rachel Lorier, Karsten Grote, Christian Sagebiel, Kumaravelu Jagavelu, Uwe J.F. Tietge, Ulrike Assmus, Konrad Streetz, Christian Hengstenberg, Marcus Fischer, Björn Mayer, Karen Maresso, Nour Eddine El Mokhtari, Stefan Schreiber, Werner Müller, Udo Bavendiek, Christina Grothusen, Helmut Drexler, Christian Trautwein, Ulrich Broeckel, Bernhard Schieffer

J Exp Med. 2007 Aug 6; 204(8): 1935–1944. doi: 10.1084/jem.20070120

PMCID:: PMC2118681

Abstract Article PDF–2.3M

Select item 117129718.

Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer.

A Kamiya, T Kinoshita, Y Ito, T Matsui, Y Morikawa, E Senba, K Nakashima, T Taga, K Yoshida, T Kishimoto, A Miyajima

EMBO J. 1999 Apr 15; 18(8): 2127–2136. doi: 10.1093/emboj/18.8.2127

PMCID:: PMC1171297

Summary PDF–498K

Select item 39541519.

Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction.

D J Hilton, A A Hilton, A Raicevic, S Rakar, M Harrison-Smith, N M Gough, C G Begley, D Metcalf, N A Nicola, T A Willson

EMBO J. 1994 Oct 17; 13(20): 4765–4775. doi: 10.1002/j.1460-2075.1994.tb06802.x

PMCID:: PMC395415

Summary Page Browse PDF–1.8M

Select item 38733320.

Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor

Damien Derouet, François Rousseau, Fabienne Alfonsi, Josy Froger, Jacques Hermann, Fabien Barbier, David Perret, Caroline Diveu, Catherine Guillet, Laurence Preisser, Agnès Dumont, Maud Barbado, Alain Morel, Odile deLapeyrière, Hugues Gascan, Sylvie Chevalier

Proc Natl Acad Sci U S A. 2004 Apr 6; 101(14): 4827–4832. Published online 2004 Mar 29. doi: 10.1073/pnas.0306178101

PMCID:: PMC387333

Abstract Article PDF–710K

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