PMC Links for GEO Profiles (Select 132647355) - PMC

Select item 98614601.

CHAC1 as a Novel Contributor of Ferroptosis in Retinal Pigment Epithelial Cells with Oxidative Damage

Ye Liu, Di Wu, Qiuli Fu, Shengjie Hao, Yuzhou Gu, Wei Zhao, Shuying Chen, Feiyin Sheng, Yili Xu, Zhiqing Chen, Ke Yao

Int J Mol Sci. 2023 Jan; 24(2): 1582. Published online 2023 Jan 13. doi: 10.3390/ijms24021582

PMCID:: PMC9861460

Select item 83529642.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80344644.

Deng Li, Shiwei Liu, Jie Xu, Lei Chen, Chaoliang Xu, Feiteng Chen, Zijie Xu, Yu Zhang, Shujie Xia, Yi Shao, Yi Wang

J Cell Mol Med. 2021 Apr; 25(7): 3610–3621. Published online 2021 Mar 16. doi: 10.1111/jcmm.16458

Correction in:: J Cell Mol Med. 2022 Sep; 26(18): 4874–4875.

PMCID:: PMC8034464

Abstract Article PDF–2.8M

Select item 66180685.

CHAC1 overexpression in human gastric parietal cells with Helicobacter pylori infection in the secretory canaliculi

Tomohisa Ogawa, Yuriko Wada, Kosuke Takemura, Philip G. Board, Keisuke Uchida, Keisuke Kitagaki, Tomoki Tamura, Takashige Suzuki, Yutaka Tokairin, Yasuaki Nakajima, Yoshinobu Eishi

Helicobacter. 2019 Aug; 24(4): e12598. Published online 2019 May 20. doi: 10.1111/hel.12598

PMCID:: PMC6618068

Abstract Article PDF–2.6M

Select item 62820096.

CHAC1 Is Differentially Expressed in Normal and Cystic Fibrosis Bronchial Epithelial Cells and Regulates the Inflammatory Response Induced by Pseudomonas aeruginosa

Léa Perra, Viviane Balloy, Tobias Foussignière, Didier Moissenet, Hortense Petat, Imran N. Mungrue, Lhousseine Touqui, Harriet Corvol, Michel Chignard, Loic Guillot

Front Immunol. 2018; 9: 2823. Published online 2018 Nov 29. doi: 10.3389/fimmu.2018.02823

PMCID:: PMC6282009

Abstract Article PDF–1.1M

Select item 52417387.

ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione

Amandeep Kaur, Ruchi Gautam, Ritika Srivastava, Avinash Chandel, Akhilesh Kumar, Subramanian Karthikeyan, Anand Kumar Bachhawat

J Biol Chem. 2017 Jan 13; 292(2): 638–651. Published online 2016 Dec 2. doi: 10.1074/jbc.M116.727479

PMCID:: PMC5241738

Abstract Article PDF–2.4M

Select item 45054948.

Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element

Rebecca R. Crawford, Eugenia T. Prescott, Charity F. Sylvester, Ashlee N. Higdon, Jixiu Shan, Michael S. Kilberg, Imran N. Mungrue

J Biol Chem. 2015 Jun 19; 290(25): 15878–15891. Published online 2015 Apr 30. doi: 10.1074/jbc.M114.635144

PMCID:: PMC4505494

Abstract Article PDF–2.8M

Select item 40316499.

Botch is a γ-glutamyl Cyclotransferase that Deglycinates and Antagonizes Notch

Zhikai Chi, Sean T. Byrne, Andrew Dolinko, Maged M. Harraz, Min-Sik Kim, George Umanah, Jun Zhong, Rong Chen, Jianmin Zhang, Jinchong Xu, Li Chen, Akhilesh Pandey, Ted M. Dawson, Valina L. Dawson

Cell Rep. Author manuscript; available in PMC 2014 May 23.

Published in final edited form as: Cell Rep. 2014 May 8; 7(3): 681–688. Published online 2014 Apr 24. doi: 10.1016/j.celrep.2014.03.048

PMCID:: PMC4031649

Abstract Article PDF–1.1M

Select item 354446510.

Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1

Nam E Joo, Kathryn Ritchie, Pachiyappan Kamarajan, Di Miao, Yvonne L Kapila

Cancer Med. 2012 Dec; 1(3): 295–305. Published online 2012 Oct 2. doi: 10.1002/cam4.35

PMCID:: PMC3544465

Abstract Article PDF–432K

Select item 351240111.

Mammalian proapoptotic factor ChaC1 and its homologues function as γ-glutamyl cyclotransferases acting specifically on glutathione

Akhilesh Kumar, Shweta Tikoo, Shuvadeep Maity, Shantanu Sengupta, Sagar Sengupta, Amandeep Kaur, Anand Kumar Bachhawat

EMBO Rep. 2012 Dec; 13(12): 1095–1101. Published online 2012 Oct 16. doi: 10.1038/embor.2012.156

PMCID:: PMC3512401

Abstract Article PDF–703K

Select item 334973412.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695

PMCID:: PMC3349734

Abstract Article PDF–377K

Select item 333193513.

Botch (NPG7) Promotes Neurogenesis by Antagonizing Notch

Zhikai Chi, Jianmin Zhang, Akinori Tokunaga, Maged M. Harraz, Sean T. Byrne, Andrew Dolinko, Jing Xu, Seth Blackshaw, Nicholas Gaiano, Ted M. Dawson, Valina L. Dawson

Dev Cell. Author manuscript; available in PMC 2013 Apr 17.

Published in final edited form as: Dev Cell. 2012 Apr 17; 22(4): 707–720. Published online 2012 Mar 22. doi: 10.1016/j.devcel.2012.02.011