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Items: 1 to 20 of 55

1.
Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19
Maximilian Peter Götz, Mikkel-Ole Skjoedt, Rafael Bayarri-Olmos, Cecilie Bo Hansen, Laura Pérez-Alós, Ida Jarlhelt, Thomas Benfield, Anne Rosbjerg, Peter Garred
J Innate Immun. 2023 Jan-Dec; 15(1): 122–135. Published online 2022 Jul 11. doi: 10.1159/000525508
PMCID:
PMC10643890
AbstractArticlePDF–577K
2.
MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence
Sonia Elhadad, David Redmond, Jenny Huang, Adrian Tan, Jeffrey Laurence
Clin Exp Immunol. 2023 Aug; 213(2): 252–264. Published online 2023 May 16. doi: 10.1093/cei/uxad055
PMCID:
PMC10361744
AbstractArticlePDF–999K
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Mannose-binding lectin gene 2 variant DD (rs 5030737) is associated with susceptibility to COVID-19 infection in the urban population of Patna City (India)
Sadhana Sharma, Bandana Kumari, Asgar Ali, Pankaj Kumar Patel, Abhay Kumar Sharma, Rathish Nair, Prabhat Kumar Singh, Krishnan Hajela
Mol Genet Genomics. 2023; 298(4): 955–963. Published online 2023 May 18. doi: 10.1007/s00438-023-02030-4
PMCID:
PMC10196310
AbstractArticlePDF–839K
5.
Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel
Rikke Zachar, Steffen Thiel, Søren Hansen, Maiken Lumby Henriksen, Mikkel-Ole Skjoedt, Karsten Skjodt, Zohra Hamzaei, Kirsten Madsen, Lars Lund, Edith Hummler, Per Svenningsen, Boye Lagerbon Jensen
Sci Rep. 2022; 12: 15955. Published online 2022 Sep 24. doi: 10.1038/s41598-022-20213-8
PMCID:
PMC9509361
AbstractArticlePDF–2.0M
6.
Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation
Ting Gao, Lin Zhu, Hainan Liu, Xiaopeng Zhang, Tingting Wang, Yangbo Fu, Hongzhen Li, Qincai Dong, Yong Hu, Zhang Zhang, Jing Jin, Zijing Liu, Weihong Yang, Yaoning Liu, Yanwen Jin, Kaitong Li, Yongjiu Xiao, Junli Liu, Huailong Zhao, Yue Liu, Ping Li, Jibo Song, Lu Zhang, Yuwei Gao, Sisi Kang, Shoudeng Chen, Qingjun Ma, Xiuwu Bian, Wei Chen, Xuan Liu, Qing Mao, Cheng Cao
Signal Transduct Target Ther. 2022; 7: 318. Published online 2022 Sep 14. doi: 10.1038/s41392-022-01133-5
PMCID:
PMC9470675
AbstractArticlePDF–6.1M
7.
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation
Zoltán Attila Nagy, Dávid Héja, Dániel Bencze, Bence Kiss, Eszter Boros, Dávid Szakács, Krisztián Fodor, Matthias Wilmanns, Andrea Kocsis, József Dobó, Péter Gál, Veronika Harmat, Gábor Pál
J Biol Chem. 2022 Jun; 298(6): 101985. Published online 2022 Apr 25. doi: 10.1016/j.jbc.2022.101985
Correction in:
J Biol Chem. 2023 Jan; 299(1): 102807.
PMCID:
PMC9136129
AbstractArticlePDF–3.1M
8.
Impact of MASP2 gene polymorphism and gene-tea drinking interaction on susceptibility to tuberculosis
Zihao Li, Mian Wang, Hua Zhong, Xin Huang, Xinyin Wu, Xian Zhang, Jing Wang, Jing Deng, Mengshi Chen, Lizhang Chen, Hongzhuan Tan
Sci Rep. 2021; 11: 6544. Published online 2021 Mar 22. doi: 10.1038/s41598-021-86129-x
PMCID:
PMC7985323
AbstractArticlePDF–948K
9.
Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu
NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3
PMCID:
PMC7979705
AbstractArticlePDF–6.8M
10.
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele
PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975
PMCID:
PMC7758050
AbstractArticlePDF–4.2M
11.
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus
Wang‐Dong Xu, Xiao‐Yan Liu, Lin‐Chong Su, An‐Fang Huang
J Cell Mol Med. 2020 Sep; 24(18): 10432–10443. Published online 2020 Jul 17. doi: 10.1111/jcmm.15656
PMCID:
PMC7521335
AbstractArticlePDF–560K
12.
MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti‐MASP2 antibody narsoplimab
S. Elhadad, J. Chapin, D. Copertino, K. Van Besien, J. Ahamed, J. Laurence
Clin Exp Immunol. 2021 Jan; 203(1): 96–104. Published online 2020 Aug 5. doi: 10.1111/cei.13497
PMCID:
PMC7405159
AbstractArticlePDF–326K
13.
Should MASP-2 Deficiency Be Considered a Primary Immunodeficiency? Relevance of the Lectin Pathway
M. Isabel García-Laorden, Elisa Hernández-Brito, Carmen Muñoz-Almagro, Svetlana Pavlovic-Nesic, Iñigo Rúa-Figueroa, M. Luisa Briones, Olga Rajas, Luis Borderías, Antoni Payeras, Leonardo Lorente, Jordi Freixinet, Jose Ferreres, Ignacio Obando, Nereida González-Quevedo, Felipe Rodríguez de Castro, Jordi Solé-Violán, Carlos Rodríguez-Gallego
J Clin Immunol. 2020; 40(1): 203–210. Published online 2019 Dec 11. doi: 10.1007/s10875-019-00714-4
PMCID:
PMC7223972
AbstractArticlePDF–409K
14.
MASP2 gene polymorphism is associated with susceptibility to hepatitis C virus infection
Siumara Tulio, Fabio R. Faucz, Renata I. Werneck, Márcia Olandoski, Rodrigo B. Alexandre, Angélica B.W. Boldt, Maria Lucia Pedroso, Iara J. de Messias-Reason
Hum Immunol. 2011 Oct; 72(10): 912–915. Published online 2011 Jul 31. doi: 10.1016/j.humimm.2011.06.016
PMCID:
PMC7115369
AbstractArticlePDF–249K
15.
MBL-associated serine proteases (MASPs) and infectious diseases
Marcia H. Beltrame, Angelica B.W. Boldt, Sandra J. Catarino, Hellen C. Mendes, Stefanie E. Boschmann, Isabela Goeldner, Iara Messias-Reason
Mol Immunol. 2015 Sep; 67(1): 85–100. Published online 2015 Apr 8. doi: 10.1016/j.molimm.2015.03.245
PMCID:
PMC7112674
AbstractArticlePDF–1.1M
16.
MAp19, the alternative splice product of the MASP2 gene
Søren E. Degn, Steffen Thiel, Ole Nielsen, Annette G. Hansen, Rudi Steffensen, Jens C. Jensenius
J Immunol Methods. 2011 Oct 28; 373(1): 89–101. Published online 2011 Aug 17. doi: 10.1016/j.jim.2011.08.006
PMCID:
PMC7099877
AbstractArticlePDF–1.2M
17.
Herpes simplex encephalitis in adult patients with MASP-2 deficiency
Stéphanie Bibert, Jocelyne Piret, Mathieu Quinodoz, Emilie Collinet, Vincent Zoete, Olivier Michielin, Rafik Menasria, Pascal Meylan, Titus Bihl, Véronique Erard, Florence Fellmann, Carlo Rivolta, Guy Boivin, Pierre-Yves Bochud
PLoS Pathog. 2019 Dec; 15(12): e1008168. Published online 2019 Dec 23. doi: 10.1371/journal.ppat.1008168
PMCID:
PMC6944389
AbstractArticlePDF–2.4M
18.
Mannose-Binding Lectin and Mannose-Binding Lectin-Associated Serine Protease-2 Genotypes and Serum Levels in Patients with Sporotrichosis
Fangfang Bao, Xi’an Fu, Gongqi Yu, Zhenzhen Wang, Hong Liu, Furen Zhang
Am J Trop Med Hyg. 2019 Dec; 101(6): 1322–1324. Published online 2019 Sep 23. doi: 10.4269/ajtmh.19-0470
PMCID:
PMC6896860
AbstractArticlePDF–212K
19.
Collectin-11/MASP Complex Formation Triggers Activation of the Lectin Complement Pathway - The Fifth Lectin Pathway Initiation Complex
Ying Jie Ma, Mikkel-Ole Skjoedt, Peter Garred
J Innate Immun. 2013 Apr; 5(3): 242–250. Published online 2012 Dec 4. doi: 10.1159/000345356
PMCID:
PMC6741501
AbstractArticlePDF–378K
20.
Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors
Dávid Szakács, Andrea Kocsis, Róbert Szász, Péter Gál, Gábor Pál
J Biol Chem. 2019 May 17; 294(20): 8227–8237. Published online 2019 Apr 5. doi: 10.1074/jbc.RA119.008315
PMCID:
PMC6527154
AbstractArticlePDF–1.3M

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