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Items: 1 to 20 of 270

1.
ISG15 accelerates acute kidney injury and the subsequent AKI-to-CKD transition by promoting TGFβR1 ISGylation
Na Cui, Chengyu Liu, Xiang Tang, Liangliang Song, Zixuan Xiao, Chen Wang, Yancai Wu, Yihao Zhou, Chentai Peng, Yuxia Liu, Ling Zheng, Xinran Liu, Kun Huang, Hong Chen
Theranostics. 2024; 14(11): 4536–4553. Published online 2024 Jul 22. doi: 10.7150/thno.95796
PMCID:
PMC11303071
AbstractArticlePDF–15M
2.
LncRNA LITATS1 suppresses TGF‐β‐induced EMT and cancer cell plasticity by potentiating TβRI degradation
Chuannan Fan, Qian Wang, Thomas B Kuipers, Davy Cats, Prasanna Vasudevan Iyengar, Sophie C Hagenaars, Wilma E Mesker, Peter Devilee, Rob A E M Tollenaar, Hailiang Mei, Peter ten Dijke
EMBO J. 2023 May; 42(10): e112806. Published online 2023 Mar 30. doi: 10.15252/embj.2022112806
PMCID:
PMC10183827
AbstractArticlePDF–5.6M
3.
Truncating variants in the penultimate exon of TGFBR1 escaping nonsense-mediated mRNA decay cause Loeys-Dietz syndrome
Paola Fortugno, Rosanna Monetta, Valeria Cinquina, Chiara Rigon, Francesca Boaretto, Chiara De Luca, Nicoletta Zoppi, Luana Di Leandro, Emanuela De Domenico, Arianna Di Daniele, Rodolfo Ippoliti, Francesco Angelucci, Ernesto Di Cesare, Ruggero De Paulis, Leonardo Salviati, Marina Colombi, Francesco Brancati, Marco Ritelli
Eur J Hum Genet. 2023 May; 31(5): 596–601. Published online 2023 Jan 4. doi: 10.1038/s41431-022-01279-4
PMCID:
PMC10172188
AbstractArticlePDF–5.0M
4.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
5.
Clinical utility of TGFB1 and its receptors (TGFBR1 and TGFBR2) in thyroid nodules: evaluation based on single nucleotide polymorphisms and mRNA analysis
Karina Colombera Peres, Larissa Teodoro, Laís Helena Pereira Amaral, Elisângela Souza Teixeira, Icléia Siqueira Barreto, Leandro Luiz Lopes de Freitas, Valdemar Maximo, Lígia V. Montalli Assumpção, Natassia Elena Bufalo, Laura Sterian Ward
Arch Endocrinol Metab. 2021 Mar-Apr; 65(2): 172–184. Published online 2021 Feb 25. doi: 10.20945/2359-3997000000330
PMCID:
PMC10065325
AbstractArticlePDF–421K
6.
Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells
Xinyue Li, Navneet Kaur, Mustafa Albahrani, Adam R. Karpf, Adrian R. Black, Jennifer D. Black
J Biol Chem. 2023 Apr; 299(4): 103017. Published online 2023 Feb 13. doi: 10.1016/j.jbc.2023.103017
PMCID:
PMC10036670
AbstractArticlePDF–1.6M
7.
Therapeutic potency of compound RMY-205 for pulmonary fibrosis induced by SARS-CoV-2 nucleocapsid protein
Zhi-yuan Zhang, Cui-yu Ju, Liu-zheng Wu, Han Yan, Wen-bin Hong, Hang-zi Chen, Peng-bo Yang, Bao-Rui Wang, Tong Gou, Xiao-yan Chen, Zhi-hong Jiang, Wei-jia Wang, Tianwei Lin, Fu-nan Li, Qiao Wu
Cell Chem Biol. 2023 Mar 16; 30(3): 261–277.e8. Published online 2023 Mar 7. doi: 10.1016/j.chembiol.2023.02.004
PMCID:
PMC9990178
AbstractArticlePDF–6.9M
8.
Expanding the phenotypic spectrum of Mendelian connective tissue disorders to include prominent kidney phenotypes
Alanna Strong, Cara Skraban, Kevin Meyers, Sandra Amaral, Susan Furth, Stacey Drant, Wendy Hsiao, Lauren Galea, Jessica Gold, Nina B. Gold, Jacqueline Leonard, Sonya Lopez, Elaine H. Zackai, Reed E. Pyeritz
Am J Med Genet A. Author manuscript; available in PMC 2023 Jan 31.
Published in final edited form as: Am J Med Genet A. 2021 Dec; 185(12): 3762–3769. Published online 2021 Aug 6. doi: 10.1002/ajmg.a.62449
PMCID:
PMC9888756
AbstractArticlePDF–1.0M
9.
Opposing USP19 splice variants in TGF-β signaling and TGF-β-induced epithelial–mesenchymal transition of breast cancer cells
Jing Zhang, Maarten van Dinther, Midory Thorikay, Babak Mousavi Gourabi, Boudewijn P. T. Kruithof, Peter ten Dijke
Cell Mol Life Sci. 2023 Feb; 80(2): 43. Published online 2023 Jan 17. doi: 10.1007/s00018-022-04672-w
PMCID:
PMC9842591
AbstractArticlePDF–14M
10.
GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β‐catenin and ALK5/SMAD2/3 pathways
Jan Frohlich, Kristina Kovacovicova, Marco Raffaele, Tereza Virglova, Eliska Cizkova, Jan Kucera, Julie Bienertova‐Vasku, Martin Wabitsch, Marion Peyrou, Francesca Bonomini, Rita Rezzani, George N. Chaldakov, Anton B. Tonchev, Michelino Di Rosa, Nicolas Blavet, Vaclav Hejret, Manlio Vinciguerra
Cell Prolif. 2022 Oct; 55(10): e13310. Published online 2022 Aug 3. doi: 10.1111/cpr.13310
PMCID:
PMC9528760
AbstractArticlePDF–3.7M
11.
The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
Jie Song, Yang Zhou, Ihor Yakymovych, Alexej Schmidt, Chunyan Li, Carl-Henrik Heldin, Maréne Landström
eBioMedicine. 2022 Aug; 82: 104155. Published online 2022 Jul 16. doi: 10.1016/j.ebiom.2022.104155
PMCID:
PMC9386726
AbstractArticlePDF–5.3M
12.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
13.
Shenkang Injection for Treating Renal Fibrosis-Metabonomics and Regulation of E3 Ubiquitin Ligase Smurfs on TGF-β/Smads Signal Transduction
Junju Zou, Xiaotao Zhou, Xian Chen, Yuerong Ma, Rong Yu
Front Pharmacol. 2022; 13: 849832. Published online 2022 Jun 2. doi: 10.3389/fphar.2022.849832
PMCID:
PMC9201572
AbstractArticlePDF–7.1M
14.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
15.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
16.
Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration
Michèle MG Hillege, Andi Shi, Ricardo A Galli, Gang Wu, Philippe Bertolino, Willem MH Hoogaars, Richard T Jaspers
eLife. 2022; 11: e77610. Published online 2022 Mar 24. doi: 10.7554/eLife.77610
PMCID:
PMC9005187
AbstractArticlePDF–8.5M
17.
Role of TGF-Beta Signaling in Beta Cell Proliferation and Function in Diabetes
Hong-Lian Wang, Li Wang, Chang-Ying Zhao, Hui-Yao Lan
Biomolecules. 2022 Mar; 12(3): 373. Published online 2022 Feb 26. doi: 10.3390/biom12030373
PMCID:
PMC8945211
AbstractArticlePDF–1.2M
18.
Ameliorating role of microRNA-378 carried by umbilical cord mesenchymal stem cells-released extracellular vesicles in mesangial proliferative glomerulonephritis
Wenbiao Chen, Feng Zhang, Xianliang Hou, Huixuan Xu, Donge Tang
Cell Commun Signal. 2022; 20: 28. Published online 2022 Mar 9. doi: 10.1186/s12964-022-00835-1
PMCID:
PMC8905735
AbstractArticlePDF–11M
19.
Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network
Rebecca Elizabeth Kattan, Han Han, Gayoung Seo, Bing Yang, Yongqi Lin, Max Dotson, Stephanie Pham, Yahya Menely, Wenqi Wang
Mol Cell Proteomics. 2022 Feb; 21(2): 100195. Published online 2022 Jan 8. doi: 10.1016/j.mcpro.2022.100195
PMCID:
PMC8864472
AbstractArticlePDF–3.6M
20.
SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability
Manami Hiraiwa, Kazuya Fukasawa, Takashi Iezaki, Hemragul Sabit, Tetsuhiro Horie, Kazuya Tokumura, Sayuki Iwahashi, Misato Murata, Masaki Kobayashi, Akane Suzuki, Gyujin Park, Katsuyuki Kaneda, Tomoki Todo, Atsushi Hirao, Mitsutoshi Nakada, Eiichi Hinoi
Commun Biol. 2022; 5: 22. Published online 2022 Jan 11. doi: 10.1038/s42003-021-02950-0
PMCID:
PMC8752672
AbstractArticlePDF–3.3M

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