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Items: 1 to 20 of 25

1.
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia
Yu-Han H. Hsu, Greta Pintacuda, Ruize Liu, Eugeniu Nacu, April Kim, Kalliopi Tsafou, Natalie Petrossian, William Crotty, Jung Min Suh, Jackson Riseman, Jacqueline M. Martin, Julia C. Biagini, Daya Mena, Joshua K.T. Ching, Edyta Malolepsza, Taibo Li, Tarjinder Singh, Tian Ge, Shawn B. Egri, Benjamin Tanenbaum, Caroline R. Stanclift, Annie M. Apffel, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Steven A. Carr, Monica Schenone, Jake Jaffe, Nadine Fornelos, Hailiang Huang, Kevin C. Eggan, Kasper Lage
iScience. 2023 May 19; 26(5): 106701. Published online 2023 Apr 18. doi: 10.1016/j.isci.2023.106701
PMCID:
PMC10189495
AbstractArticlePDF–5.3M
2.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
3.
RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy
Tomasz Radaszkiewicz, Michaela Nosková, Kristína Gömöryová, Olga Vondálová Blanářová, Katarzyna Anna Radaszkiewicz, Markéta Picková, Ráchel Víchová, Tomáš Gybeľ, Karol Kaiser, Lucia Demková, Lucia Kučerová, Tomáš Bárta, David Potěšil, Zbyněk Zdráhal, Karel Souček, Vítězslav Bryja
eLife. 2021; 10: e65759. Published online 2021 Oct 27. doi: 10.7554/eLife.65759
PMCID:
PMC8550759
AbstractArticlePDF–7.4M
4.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
5.
Retinal Proteomics of a Mouse Model of Dystroglycanopathies Reveals Molecular Alterations in Photoreceptors
Mary Luz Uribe, José Martín-Nieto, Cristina Quereda, Marcos Rubio-Fernández, Jesús Cruces, George M. C. Janssen, Arnoud H. de Ru, Peter A. van Veelen, Paul J. Hensbergen
J Proteome Res. 2021 Jun 4; 20(6): 3268–3277. Published online 2021 May 24. doi: 10.1021/acs.jproteome.1c00126
PMCID:
PMC8280732
AbstractArticlePDF–4.8M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
KIAA1549‐BRAF Fusions and IDH Mutations Can Coexist in Diffuse Gliomas of Adults
Manuela Badiali, Vincent Gleize, Sophie Paris, Loredana Moi, Selma Elhouadani, Antonietta Arcella, Roberta Morace, Manila Antonelli, Francesca Romana Buttarelli, Dominique Figarella‐ Branger, Young‐Ho Kim, Hiroko Ohgaki, Karima Mokhtari, Marc Sanson, Felice Giangaspero
Brain Pathol. 2012 Nov; 22(6): 841–847. Published online 2012 Jun 18. doi: 10.1111/j.1750-3639.2012.00603.x
PMCID:
PMC8057621
AbstractArticlePDF–905K
8.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
9.
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari
Mol Cell. Author manuscript; available in PMC 2020 Feb 21.
Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001
PMCID:
PMC6386588
AbstractArticlePDF–1.7M
10.
KIAA1549-BRAF Expression Establishes a Permissive Tumor Microenvironment Through NFκB-Mediated CCL2 Production
Ran Chen, Chanel Keoni, Christopher A. Waker, Robert M. Lober, David H. Gutmann
Neoplasia. 2019 Jan; 21(1): 52–60. Published online 2018 Nov 30. doi: 10.1016/j.neo.2018.11.007
Correction in:
Neoplasia. 2020 Mar; 22(3): e1.
PMCID:
PMC6277251
AbstractArticlePDF–1.6M
11.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
12.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
13.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
14.
A dynamic protein interaction landscape of the human centrosome-cilium interface
Gagan D. Gupta, Étienne Coyaud, João Gonçalves, Bahareh A. Mojarad, Yi Liu, Qianzhu Wu, Ladan Gheiratmand, David Comartin, Johnny M. Tkach, Sally W.T. Cheung, Mikhail Bashkurov, Monica Hasegan, James D. Knight, Zhen-Yuan Lin, Markus Schueler, Friedhelm Hildebrandt, Jason Moffat, Anne-Claude Gingras, Brian Raught, Laurence Pelletier
Cell. Author manuscript; available in PMC 2016 Dec 3.
Published in final edited form as: Cell. 2015 Dec 3; 163(6): 1484–1499. doi: 10.1016/j.cell.2015.10.065
PMCID:
PMC5089374
AbstractArticlePDF–1.5M
15.
Whole Chromosome 7 Gain Predicts Higher Risk of Recurrence in Pediatric Pilocytic Astrocytomas Independently From KIAA1549-BRAF Fusion Status
Jacquelyn J. Roth, Tamara M. Fierst, Angela J. Waanders, Li Yimei, Jaclyn A. Biegel, Mariarita Santi
J Neuropathol Exp Neurol. 2016 Apr; 75(4): 306–315. Published online 2016 Mar 1. doi: 10.1093/jnen/nlw001
PMCID:
PMC5009478
AbstractArticlePDF–1.3M
16.
BRAF Alterations in Primary Glial and Glioneuronal Neoplasms of the Central Nervous System With Identification of 2 Novel KIAA1549:BRAF Fusion Variants
Alex Lin, Fausto J. Rodriguez, Matthias A. Karajannis, Susan C. Williams, Genevieve Legault, David Zagzag, Peter C. Burger, Jeffrey C. Allen, Charles G. Eberhart, Eli E. Bar
J Neuropathol Exp Neurol. Author manuscript; available in PMC 2015 Nov 2.
Published in final edited form as: J Neuropathol Exp Neurol. 2012 Jan; 71(1): 66–72. doi: 10.1097/NEN.0b013e31823f2cb0
PMCID:
PMC4629834
AbstractArticlePDF–1.2M
17.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
18.
KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas
Aline Paixão Becker, Cristovam Scapulatempo-Neto, Adriana C. Carloni, Alessandra Paulino, Jamie Sheren, Dara L. Aisner, Evelyn Musselwhite, Carlos Clara, Hélio R. Machado, Ricardo S. Oliveira, Luciano Neder, Marileila Varella-Garcia, Rui M. Reis
J Neuropathol Exp Neurol. 2015 Jul; 74(7): 743–754. Published online 2015 Jun 16. doi: 10.1097/NEN.0000000000000213
PMCID:
PMC4470527
AbstractArticlePDF–3.2M
19.
Characterization of LGALS3 (galectin-3) as a player in DNA damage response
Renato S Carvalho, Vanessa C Fernandes, Thales C Nepomuceno, Deivid C Rodrigues, Nicholas T Woods, Guilherme Suarez-Kurtz, Roger Chammas, Alvaro N Monteiro, Marcelo A Carvalho
Cancer Biol Ther. 2014 Jul 1; 15(7): 840–850. Published online 2014 Apr 22. doi: 10.4161/cbt.28873
PMCID:
PMC4100985
AbstractArticlePDF–1.6M
20.
Posterior fossa and spinal gangliogliomas form two distinct clinicopathologic and molecular subgroups
Kirti Gupta, Wilda Orisme, Julie H Harreld, Ibrahim Qaddoumi, James D Dalton, Chandanamali Punchihewa, Racquel Collins-Underwood, Thomas Robertson, Ruth G Tatevossian, David W Ellison
Acta Neuropathol Commun. 2014; 2: 18. Published online 2014 Feb 14. doi: 10.1186/2051-5960-2-18
PMCID:
PMC3931494
AbstractArticlePDF–1.6M

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