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Select item 112363201.

NAT1 inhibits liver metastasis of colorectal cancer by regulating EMT and glycolysis

Wang Gu, Chen Li, Tingting Shen, Li Tong, Wenkang Yuan, Xiaofei Zheng, Tianqi Wang, Siyu Wang, Benshuai Zhu, Chong Zhang, Chao Zhang

Aging (Albany NY) 2024 Jun 30; 16(12): 10546–10562. Published online 2024 Jun 24. doi: 10.18632/aging.205957

PMCID:: PMC11236320

Abstract Article PDF–1.8M

Select item 101935322.

Upregulation of cytidine deaminase in NAT1 knockout breast cancer cells

Kyung U. Hong, Afi H. Tagnedji, Mark A. Doll, Kennedy M. Walls, David W. Hein

J Cancer Res Clin Oncol. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: J Cancer Res Clin Oncol. 2023 Jul; 149(8): 5047–5060. Published online 2022 Nov 3. doi: 10.1007/s00432-022-04436-w

PMCID:: PMC10193532

Abstract Article PDF–1.2M

Select item 101880413.

Altered Arylamine N-acetyltransferase 1 and miR-1290 Levels in Childhood Acute Lymphoblastic Leukemia: A Pilot Study

OSWALDO HERNANDEZ-GONZALEZ, ROSA DEL CARMEN MILAN-SEGOVIA, DANIEL ZAVALA-REYES, DINORA MARGARITA ALVARADO-ZAMARRIPA, JUAN JOSE ORTIZ-ZAMUDIO, LOURDES CECILIA CORREA-GONZALEZ, JUAN MANUEL VARGAS-MORALES, EDITH ELENA URESTI-RIVERA, DIANA PATRICIA PORTALES-PEREZ

In Vivo. 2023 May-Jun; 37(3): 1129–1144. Published online 2023 May 3. doi: 10.21873/invivo.13188

PMCID:: PMC10188041

Abstract Article PDF–5.2M

Select item 94647504.

Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis

Courtney E. McAleese, Neville J. Butcher, Rodney F. Minchin

Breast Cancer Res Treat. 2022; 195(3): 223–236. Published online 2022 Aug 2. doi: 10.1007/s10549-022-06668-3

PMCID:: PMC9464750

Abstract Article PDF–2.1M

Select item 90185115.

Deletion of arylamine N-acetyltransferase 1 in MDA-MB-231 human breast cancer cells reduces primary and secondary tumor growth in vivo with no significant effects on metastasis

Mark A. Doll, Andrew R. Ray, Raúl A. Salazar-González, Parag P. Shah, Alexis A. Vega, Sophia M. Sears, Austin M. Krueger, Kyung U. Hong, Levi J. Beverly, David W. Hein

Mol Carcinog. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Mol Carcinog. 2022 May; 61(5): 481–493. Published online 2022 Feb 8. doi: 10.1002/mc.23392

PMCID:: PMC9018511

Abstract Article PDF–1.7M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 72999367.

CRISPR/Cas9 knockout of human arylamine N-acetyltransferase 1 in MDA-MB-231 breast cancer cells suggests a role in cellular metabolism

Samantha M. Carlisle, Patrick J. Trainor, Kyung U. Hong, Mark A. Doll, David W. Hein

Sci Rep. 2020; 10: 9804. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66863-4

PMCID:: PMC7299936

Abstract Article PDF–8.4M

Select item 72749078.

NAT1 Genetic Variation Increases Asthma Risk in Children with Secondhand Smoke Exposure

Cassandra C. Brooks, Lisa J. Martin, Valentina Pilipenko, Hua He, Grace K. LeMasters, James E. Lockey, David I. Bernstein, Patrick H. Ryan, Gurjit K. Khurana Hershey, Jocelyn M. Biagini Myers

J Asthma. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: J Asthma. 2021 Mar; 58(3): 284–292. Published online 2019 Dec 6. doi: 10.1080/02770903.2019.1694941

PMCID:: PMC7274907

Abstract Article PDF–624K

Select item 71428389.

MicroRNA-6744-5p promotes anoikis in breast cancer and directly targets NAT1 enzyme

Sharan Malagobadan, Chai San Ho, Noor Hasima Nagoor

Cancer Biol Med. 2020 Feb 15; 17(1): 101–111. Published online 2020 Feb 15. doi: 10.20892/j.issn.2095-3941.2019.0010

PMCID:: PMC7142838

Abstract Article PDF–523K

Select item 696168010.

Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV

Pengcheng Li, Neville J. Butcher, Rodney F. Minchin

Cell Adh Migr. 2020; 14(1): 1–11. Published online 2020 Jan 7. doi: 10.1080/19336918.2019.1710015

PMCID:: PMC6961680

Abstract Article PDF–2.0M

Select item 635366211.

Knockout of Human Arylamine N-Acetyltransferase 1 (NAT1) in MDA-MB-231 Breast Cancer Cells Leads to Increased Reserve Capacity, Maximum Mitochondrial Capacity, and Glycolytic Reserve Capacity

Samantha M. Carlisle, Patrick J. Trainor, Mark A. Doll, Marcus W. Stepp, Carolyn M. Klinge, David W. Hein

Mol Carcinog. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Mol Carcinog. 2018 Nov; 57(11): 1458–1466. Published online 2018 Jul 18. doi: 10.1002/mc.22869

PMCID:: PMC6353662

Abstract Article PDF–2.4M

Select item 629516512.

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression

Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee, Tomonori Hosoya, Qingqing Wu, Greggory Myers, Kim-Chew Lim, Ryo Kurita, Yukio Nakamura, Anne B. Vojtek, Jean-François Rual, James Douglas Engel

Genes Dev. 2018 Dec 1; 32(23-24): 1537–1549. doi: 10.1101/gad.318436.118

PMCID:: PMC6295165

Abstract Article PDF–3.5M

Select item 620814113.

Functional expression of human arylamine N-acetyltransferase NAT1*10 and NAT1*11 alleles: a minireview

David W. Hein, Giannoulis Fakis, Sotiria Boukouvala

Pharmacogenet Genomics. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: Pharmacogenet Genomics. 2018 Oct; 28(10): 238–244. doi: 10.1097/FPC.0000000000000350

PMCID:: PMC6208141

Abstract Article PDF–363K

Select item 607446314.

N-acetyltransferase 1 and 2 polymorphisms and risk of diabetes mellitus type 2 in a Saudi population

Waleed M. Al-Shaqha, Khalid M. Alkharfy, Nasser M. Al-Daghri, Abdul Khader Mohammed

Ann Saudi Med. 2015 May-Jun; 35(3): 214–221. doi: 10.5144/0256-4947.2015.214

PMCID:: PMC6074463

Abstract Article PDF–536K

Select item 602941815.

Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance

Rodney F. Minchin, Neville J. Butcher

BMC Genomics. 2018; 19: 513. Published online 2018 Jul 3. doi: 10.1186/s12864-018-4894-4

PMCID:: PMC6029418

Abstract Article PDF–1.5M

Select item 601724116.

Retrospective analysis of estrogen receptor 1 and N-acetyltransferase gene expression in normal breast tissue, primary breast tumors, and established breast cancer cell lines

Samantha M. Carlisle, David W. Hein

Int J Oncol. 2018 Aug; 53(2): 694–702. Published online 2018 Jun 11. doi: 10.3892/ijo.2018.4436

PMCID:: PMC6017241

Abstract Article PDF–1.0M

Select item 586072717.

Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas

Zahra Montazeri, Evropi Theodoratou, Christine Nyiraneza, Maria Timofeeva, Wanjing Chen, Victoria Svinti, Shanya Sivakumaran, Gillian Gresham, Laura Cubitt, Luis Carvajal-Carmona, Monica M Bertagnolli, Ann G Zauber, Ian Tomlinson, Susan M Farrington, Malcolm G Dunlop, Harry Campbell, Julian Little

Int J Epidemiol. 2016 Feb; 45(1): 186–205. Published online 2015 Oct 7. doi: 10.1093/ije/dyv185

PMCID:: PMC5860727

Abstract Article PDF–361K

Select item 563060018.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 556003519.

Maternal smoking and oral clefts: The role of detoxification pathway genes

Rolv T. Lie, Allen J Wilcox, Jack Taylor, Håkon K. Gjessing, Ola Didrik Saugstad, Frank Aabyholm, Halvard Vindenes

Epidemiology. Author manuscript; available in PMC 2017 Aug 17.

Published in final edited form as: Epidemiology. 2008 Jul; 19(4): 606–615. doi: 10.1097/EDE.0b013e3181690731

PMCID:: PMC5560035

Abstract Article PDF–321K

Select item 555356820.

A role for mitochondrial translation in promotion of viability in K-Ras mutant cells

Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge

Cell Rep. Author manuscript; available in PMC 2017 Aug 11.

Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 427–438. doi: 10.1016/j.celrep.2017.06.061

PMCID:: PMC5553568

Abstract Article PDF–1.8M

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