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Items: 1 to 20 of 42

1.
Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation
Chenzhou Wu, Xiaomin Cai, Ying Wang, Carlos D. Rodriguez, Giorgia Zoaldi, Lydia Herrmann, Chun-Yuh Huang, Xiaoqiong Wang, Viraj R. Sanghvi, Rongze O. Lu, Zhipeng Meng
J Biol Chem. 2024 May; 300(5): 107257. Published online 2024 Apr 2. doi: 10.1016/j.jbc.2024.107257
PMCID:
PMC11067347
AbstractArticlePDF–4.4M
2.
TGF-β1-induced RAP2 regulates invasion in pancreatic cancer: RAP2 regulates invasion in pancreatic cancer
Kaizhou Jin, Chen Liu, He Cheng, Qinglin Fei, Qiuyi Huang, Zhiwen Xiao, Xianjun Yu, Weiding Wu
Acta Biochim Biophys Sin (Shanghai) 2022 Mar; 54(3): 361–369. Published online 2022 Feb 25. doi: 10.3724/abbs.2022015
PMCID:
PMC9828032
AbstractArticlePDF–6.5M
3.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
4.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
AbstractArticlePDF–2.8M
5.
LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression
Xuexue Xu, Pengsheng Ding, Lan Shi, Gang Wu, Xiaoling Ma
BMC Cancer. 2022; 22: 630. Published online 2022 Jun 8. doi: 10.1186/s12885-022-09680-4
PMCID:
PMC9175482
AbstractArticlePDF–15M
6.
Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration
Emily D. Duncan, Ke-Jun Han, Margaret A. Trout, Rytis Prekeris
J Cell Biol. 2022 Apr 4; 221(4): e202107114. Published online 2022 Mar 16. doi: 10.1083/jcb.202107114
PMCID:
PMC8931537
AbstractArticlePDF–8.7M
7.
Simulated Microgravity Increases the Permeability of HUVEC Monolayer through Up-Regulation of Rap1GAP and Decreased Rap2 Activation
Shuliang Shi, Jing Li, Erzhuo Li, Wenqi Guo, Yao He, Jinpeng Wang, Yao Zhang, Lei Yue, Lijun Wei
Int J Mol Sci. 2022 Jan; 23(2): 630. Published online 2022 Jan 6. doi: 10.3390/ijms23020630
PMCID:
PMC8776081
AbstractArticlePDF–4.4M
8.
Tumor suppressive role of miR-33a-5p in pancreatic ductal adenocarcinoma cells by directly targeting RAP2A
Yanfen Lian, Dongxiao Jiang, Jiangtao Sun
Cell Mol Biol Lett. 2021; 26: 24. Published online 2021 Jun 5. doi: 10.1186/s11658-021-00265-w
PMCID:
PMC8180020
AbstractArticlePDF–5.4M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Polo-Like Kinase (Plk2) alters the Ratio of Its GAP Activity toward HRas, Rap1 and Rap2 GTPases
Ward G. Walkup, 4th, Michael J. Sweredoski, Robert L. Graham, Sonja Hess, Mary B. Kennedy
Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Feb 19.
Published in final edited form as: Biochem Biophys Res Commun. 2018 Sep 10; 503(3): 1599–1604. Published online 2018 Jul 24. doi: 10.1016/j.bbrc.2018.07.087
PMCID:
PMC7894274
AbstractArticlePDF–1016K
11.
lncRNA FLVCR1-AS1 drives colorectal cancer progression via modulation of the miR-381/RAP2A axis
Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Mol Med Rep. 2021 Feb; 23(2): 139. Published online 2020 Dec 13. doi: 10.3892/mmr.2020.11778
PMCID:
PMC7751490
AbstractArticlePDF–9.9M
12.
Amino acids enhance polyubiquitination of Rheb and its binding to mTORC1 by blocking lysosomal ATXN3 deubiquitinase activity
Yao Yao, Sungki Hong, Takayuki Ikeda, Hiroyuki Mori, Ormond A. MacDougald, Shigeyuki Nada, Masato Okada, Ken Inoki
Mol Cell. Author manuscript; available in PMC 2021 Nov 5.
Published in final edited form as: Mol Cell. 2020 Nov 5; 80(3): 437–451.e6. doi: 10.1016/j.molcel.2020.10.004
PMCID:
PMC7665239
AbstractArticlePDF–3.2M
13.
MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
Gayoung Seo, Han Han, Rebecca Elizabeth Vargas, Bing Yang, Xu Li, Wenqi Wang
Cell Rep. Author manuscript; available in PMC 2020 Jul 25.
Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107860. doi: 10.1016/j.celrep.2020.107860
PMCID:
PMC7382313
AbstractArticlePDF–2.6M
14.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
15.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
16.
RAP2 Mediates Mechano-responses of Hippo Pathway
Zhipeng Meng, Yunjiang Qiu, Kimberly C. Lin, Aditya Kumar, Jesse K. Placone, Cao Fang, Kuei-Chun Wang, Shicong Lu, Margaret Pan, Audrey W. Hong, Toshiro Moroishi, Min Luo, Steven W. Plouffe, Yarui Diao, Zhen Ye, Hyun Woo Park, Xiaoqiong Wang, Fa-Xing Yu, Shu Chien, Cun-Yu Wang, Bing Ren, Adam J. Engler, Kun-Liang Guan
Nature. Author manuscript; available in PMC 2019 Feb 22.
Published in final edited form as: Nature. 2018 Aug; 560(7720): 655–660. Published online 2018 Aug 22. doi: 10.1038/s41586-018-0444-0
PMCID:
PMC6128698
AbstractArticlePDF–5.7M
17.
Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans
Xi Chen, Akihiro CE Shibata, Ardalan Hendi, Mizuki Kurashina, Ethan Fortes, Nicholas L Weilinger, Brian A MacVicar, Hideji Murakoshi, Kota Mizumoto
eLife. 2018; 7: e38801. Published online 2018 Jul 31. doi: 10.7554/eLife.38801
PMCID:
PMC6067881
AbstractArticlePDF–5.2M
18.
Rap2a真核表达质粒的鉴定及其对肺癌细胞迁移能力的影响
吴 金霞, 桑 苗苗, 曹 文嘉, 郑 骏年, 裴 冬生
Zhongguo Fei Ai Za Zhi. 2014 Sep 20; 17(9): 643–648. Chinese. doi: 10.3779/j.issn.1009-3419.2014.09.01
Correction in:
Zhongguo Fei Ai Za Zhi. 2021 Mar 20; 24(3): 172.
PMCID:
PMC6000507
AbstractArticlePDF–1.8M
19.
Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion by Plasmodium falciparum
Meng-Yao Zhang, Yang Zhang, Xiao-Dong Wu, Kun Zhang, Peng Lin, Hui-Jie Bian, Min-Min Qin, Wan Huang, Ding Wei, Zhao Zhang, Jiao Wu, Ruo Chen, Fei Feng, Bin Wang, Gang Nan, Ping Zhu, Zhi-Nan Chen
Blood. 2018 Mar 8; 131(10): 1111–1121. Prepublished online 2018 Jan 19. doi: 10.1182/blood-2017-08-802918
PMCID:
PMC5854849
AbstractArticle
20.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M

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