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Items: 1 to 20 of 30

1.
The ER folding sensor UGGT1 acts on TAPBPR-chaperoned peptide-free MHC I
Lina Sagert, Christian Winter, Ina Ruppert, Maximilian Zehetmaier, Christoph Thomas, Robert Tampé
eLife. 2023; 12: e85432. Published online 2023 Jun 22. doi: 10.7554/eLife.85432
PMCID:
PMC10325711
AbstractArticlePDF–1.0M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
4.
Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins
Fengwen Zhang, Trinity M. Zang, Eva M. Stevenson, Xiao Lei, Dennis C. Copertino, Talia M. Mota, Julie Boucau, Wilfredo F. Garcia-Beltran, R. Brad Jones, Paul D. Bieniasz
Proc Natl Acad Sci U S A. 2022 Oct 11; 119(41): e2209042119. Published online 2022 Sep 22. doi: 10.1073/pnas.2209042119
PMCID:
PMC9573092
AbstractArticlePDF–2.6M
5.
A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins
Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux
Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611
PMCID:
PMC8951556
AbstractArticlePDF–4.4M
6.
TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap
Andrew C. McShan, Christine A. Devlin, Giora I. Morozov, Sarah A. Overall, Danai Moschidi, Neha Akella, Erik Procko, Nikolaos G. Sgourakis
Nat Commun. 2021; 12: 3174. Published online 2021 May 26. doi: 10.1038/s41467-021-23225-6
PMCID:
PMC8154891
AbstractArticlePDF–6.5M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor
Lina Sagert, Felix Hennig, Christoph Thomas, Robert Tampé
eLife. 2020; 9: e55326. Published online 2020 Mar 13. doi: 10.7554/eLife.55326
PMCID:
PMC7117912
AbstractArticlePDF–1.5M
9.
Distinct Polymorphisms in HLA Class I Molecules Govern Their Susceptibility to Peptide Editing by TAPBPR
F. Tudor Ilca, Linnea Z. Drexhage, Gemma Brewin, Sarah Peacock, Louise H. Boyle
Cell Rep. 2019 Nov 5; 29(6): 1621–1632.e3. Published online 2019 Nov 5. doi: 10.1016/j.celrep.2019.09.074
PMCID:
PMC7057265
AbstractArticle
10.
Preferential interaction of MHC class I with TAPBPR in the absence of glycosylation
Andreas Neerincx, Louise H. Boyle
Mol Immunol. 2019 Sep; 113: 58–66. doi: 10.1016/j.molimm.2018.06.269
PMCID:
PMC6859791
AbstractArticlePDF–1.7M
11.
Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation
Jiansheng Jiang, Kannan Natarajan, Lisa F. Boyd, Giora I. Morozov, Michael G. Mage, David H. Margulies
Science. Author manuscript; available in PMC 2019 Jan 5.
Published in final edited form as: Science. 2017 Nov 24; 358(6366): 1064–1068. Published online 2017 Oct 12. doi: 10.1126/science.aao5154
PMCID:
PMC6320693
AbstractArticlePDF–896K
12.
TAPBPR mediates peptide dissociation from MHC class I using a leucine lever
F Tudor Ilca, Andreas Neerincx, Clemens Hermann, Ana Marcu, Stefan Stevanović, Janet E Deane, Louise H Boyle
eLife. 2018; 7: e40126. Published online 2018 Nov 28. doi: 10.7554/eLife.40126
PMCID:
PMC6307860
AbstractArticlePDF–3.1M
13.
Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle
Andrew C. McShan, Kannan Natarajan, Vlad K. Kumirov, David Flores-Solis, Jiansheng Jiang, Mareike Badstübner, Jugmohit S. Toor, Clive R. Bagshaw, Evgenii L. Kovrigin, David H. Margulies, Nikolaos G. Sgourakis
Nat Chem Biol. Author manuscript; available in PMC 2019 Jan 9.
Published in final edited form as: Nat Chem Biol. 2018 Aug; 14(8): 811–820. Published online 2018 Jul 9. doi: 10.1038/s41589-018-0096-2
PMCID:
PMC6202177
AbstractArticlePDF–2.1M
14.
Utilizing TAPBPR to promote exogenous peptide loading onto cell surface MHC I molecules
F. Tudor Ilca, Andreas Neerincx, Mark R. Wills, Maike de la Roche, Louise H. Boyle
Proc Natl Acad Sci U S A. 2018 Oct 2; 115(40): E9353–E9361. Published online 2018 Sep 13. doi: 10.1073/pnas.1809465115
PMCID:
PMC6176578
AbstractArticlePDF–1.1M
15.
TAPBPR bridges UDP-glucose:glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway
Andreas Neerincx, Clemens Hermann, Robin Antrobus, Andy van Hateren, Huan Cao, Nico Trautwein, Stefan Stevanović, Tim Elliott, Janet E Deane, Louise H Boyle
eLife. 2017; 6: e23049. Published online 2017 Apr 20. doi: 10.7554/eLife.23049
PMCID:
PMC5441866
AbstractArticlePDF–1.8M
16.
HIV–host interactome revealed directly from infected cells
Yang Luo, Erica Y. Jacobs, Todd M. Greco, Kevin D. Mohammed, Tommy Tong, Sarah Keegan, James M. Binley, Ileana M. Cristea, David Fenyö, Michael P. Rout, Brian T. Chait, Mark A. Muesing
Nat Microbiol. Author manuscript; available in PMC 2016 Jul 1.
Published in final edited form as: Nat Microbiol. 2016 Jul; 1(7): 16068. Published online 2016 May 23. doi: 10.1038/nmicrobiol.2016.68
PMCID:
PMC4928716
AbstractArticlePDF–1.1M
17.
Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing
Giora I. Morozov, Huaying Zhao, Michael G. Mage, Lisa F. Boyd, Jiansheng Jiang, Michael A. Dolan, Ramesh Venna, Michael A. Norcross, Curtis P. McMurtrey, William Hildebrand, Peter Schuck, Kannan Natarajan, David H. Margulies
Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8): E1006–E1015. Published online 2016 Feb 11. doi: 10.1073/pnas.1519894113
PMCID:
PMC4776512
AbstractArticlePDF–1.9M
18.
TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst
Clemens Hermann, Andy van Hateren, Nico Trautwein, Andreas Neerincx, Patrick J Duriez, Stefan Stevanović, John Trowsdale, Janet E Deane, Tim Elliott, Louise H Boyle
eLife. 2015; 4: e09617. Published online 2015 Oct 6. doi: 10.7554/eLife.09617
PMCID:
PMC4718805
AbstractArticlePDF–2.3M
19.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
20.
TAPBPR isoforms exhibit altered association with MHC class I
Keith M Porter, Clemens Hermann, James A Traherne, Louise H Boyle
Immunology. 2014 Jun; 142(2): 289–299. Published online 2014 Apr 24. doi: 10.1111/imm.12253
PMCID:
PMC4008236
AbstractArticlePDF–1.7M

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