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Select item 110502861.

Investigating the Impact of Electrostatic Interactions on Calmodulin Binding and Ca²⁺-Dependent Activation of the Calcium-Gated Potassium SK4 Channel

Émilie Segura, Juan Zhao, Marlena Broszczak, Frédéric Audet, Rémy Sauvé, Lucie Parent

Int J Mol Sci. 2024 Apr; 25(8): 4255. Published online 2024 Apr 11. doi: 10.3390/ijms25084255

PMCID:: PMC11050286

Abstract Article PDF–3.5M

Select item 109521952.

A single coiled‐coil domain mutation in hIKCa channel subunits disrupts preferential formation of heteromeric hSK1:hIKCa channels

James N. Charlick, Daniella Bozadzhieva, Andrew S. Butler, Kevin A. Wilkinson, Neil V. Marrion

Eur J Neurosci. 2024 Jan; 59(1): 3–16. Published online 2023 Nov 29. doi: 10.1111/ejn.16189

PMCID:: PMC10952195

Abstract Article PDF–8.4M

Select item 109168663.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 108553614.

The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells

Polina Petkova-Kirova, Nicoletta Murciano, Giulia Iacono, Julia Jansen, Greta Simionato, Min Qiao, Carmen Van der Zwaan, Maria Giustina Rotordam, Thomas John, Laura Hertz, Arjan J. Hoogendijk, Nadine Becker, Christian Wagner, Marieke Von Lindern, Stephane Egee, Emile Van den Akker, Lars Kaestner

Int J Mol Sci. 2024 Feb; 25(3): 1416. Published online 2024 Jan 24. doi: 10.3390/ijms25031416

PMCID:: PMC10855361

Abstract Article PDF–4.1M

Select item 93689155.

Downregulation of IL-8 and IL-10 by the Activation of Ca²⁺-Activated K⁺ Channel K_Ca3.1 in THP-1-Derived M₂ Macrophages

Susumu Ohya, Miki Matsui, Junko Kajikuri, Hiroaki Kito, Kyoko Endo

Int J Mol Sci. 2022 Aug; 23(15): 8603. Published online 2022 Aug 3. doi: 10.3390/ijms23158603

PMCID:: PMC9368915

Abstract Article PDF–6.0M

Select item 92664066.

KCNN4 Promotes the Stemness Potentials of Liver Cancer Stem Cells by Enhancing Glucose Metabolism

Jing Fan, Ruofei Tian, Xiangmin Yang, Hao Wang, Ying Shi, Xinyu Fan, Jiajia Zhang, Yatong Chen, Kun Zhang, Zhinan Chen, Ling Li

Int J Mol Sci. 2022 Jul; 23(13): 6958. Published online 2022 Jun 23. doi: 10.3390/ijms23136958

PMCID:: PMC9266406

Abstract Article PDF–19M

Select item 83939657.

TRPM2 Oxidation Activates Two Distinct Potassium Channels in Melanoma Cells through Intracellular Calcium Increase

Loretta Ferrera, Raffaella Barbieri, Cristiana Picco, Paolo Zuccolini, Alessia Remigante, Sara Bertelli, Maria Rita Fumagalli, Giovanni Zifarelli, Caterina A. M. La Porta, Paola Gavazzo, Michael Pusch

Int J Mol Sci. 2021 Aug; 22(16): 8359. Published online 2021 Aug 4. doi: 10.3390/ijms22168359

PMCID:: PMC8393965

Abstract Article PDF–4.2M

Select item 83682108.

Electrophysiological engineering of heart-derived cells with calcium-dependent potassium channels improves cell therapy efficacy for cardioprotection

Patrick Vigneault, Sandrine Parent, Pushpinder Kanda, Connor Michie, Darryl R. Davis, Stanley Nattel

Nat Commun. 2021; 12: 4963. Published online 2021 Aug 16. doi: 10.1038/s41467-021-25180-8

PMCID:: PMC8368210

Abstract Article PDF–2.6M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 794897910.

K_Ca3.1-dependent uptake of the cytotoxic DNA-binding dye Hoechst 33258 into cancerous but not healthy cervical cells

Maurish Bukhari, Han Deng, Darren Sipes, Marisa Ruane-Foster, Kayla Purdy, Craig D. Woodworth, Shantanu Sur, Damien S.K. Samways

J Biol Chem. 2021 Jan-Jun; 296: 100084. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.013997

PMCID:: PMC7948979

Abstract Article PDF–2.8M

Select item 788344911.

ATP-evoked intracellular Ca²⁺ transients shape the ionic permeability of human microglia from epileptic temporal cortex

Nicole Piera Palomba, Katiuscia Martinello, Germana Cocozza, Sara Casciato, Addolorata Mascia, Giancarlo Di Gennaro, Roberta Morace, Vincenzo Esposito, Heike Wulff, Cristina Limatola, Sergio Fucile

J Neuroinflammation. 2021; 18: 44. Published online 2021 Feb 15. doi: 10.1186/s12974-021-02096-0

PMCID:: PMC7883449

Abstract Article PDF–1.0M

Select item 748572312.

KCNN4 is a diagnostic and prognostic biomarker that promotes papillary thyroid cancer progression

Jialiang Wen, Bangyi Lin, Lizhi Lin, Yizuo Chen, Ouchen Wang

Aging (Albany NY) 2020 Aug 31; 12(16): 16437–16456. Published online 2020 Aug 28. doi: 10.18632/aging.103710

PMCID:: PMC7485723

Abstract Article PDF–2.5M

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 666913814.

Clinical and biological features in PIEZO1-hereditary xerocytosis and Gardos channelopathy: a retrospective series of 126 patients

Véronique Picard, Corinne Guitton, Isabelle Thuret, Christian Rose, Laurence Bendelac, Kaldoun Ghazal, Patricia Aguilar-Martinez, Catherine Badens, Claire Barro, Claire Bénéteau, Claire Berger, Pascal Cathébras, Eric Deconinck, Jacques Delaunay, Jean-Marc Durand, Nadia Firah, Frédéric Galactéros, Bertrand Godeau, Xavier Jaïs, Jean-Pierre de Jaureguiberry, Camille Le Stradic, François Lifermann, Robert Maffre, Gilles Morin, Julien Perrin, Valérie Proulle, Marc Ruivard, Fabienne Toutain, Agnès Lahary, Loïc Garçon

Haematologica. 2019 Aug; 104(8): 1554–1564. Prepublished online 2019 Jan 24. doi: 10.3324/haematol.2018.205328