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Select item 109385881.

Integrated single-cell transcriptomic and epigenetic study of cell state transition and lineage commitment in embryonic mouse cerebellum

Nagham Khouri-Farah, Qiuxia Guo, Kerry Morgan, Jihye Shin, James Y. H. Li

Sci Adv. 2022 Apr; 8(13): eabl9156. Published online 2022 Apr 1. doi: 10.1126/sciadv.abl9156

PMCID:: PMC10938588

Abstract Article PDF–16M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108534533.

Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi

Hong-Nhung Tran, Quy-Hoai Nguyen, Yongsu Jeong

Front Cell Dev Biol. 2024; 12: 1336308. Published online 2024 Jan 26. doi: 10.3389/fcell.2024.1336308

PMCID:: PMC10853453

Abstract Article PDF–8.4M

Select item 105454374.

DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons

Arquimedes Cheffer, Marta Garcia-Miralles, Esther Maier, Ipek Akol, Henriette Franz, Vandana Shree Vedartham Srinivasan, Tanja Vogel

Cereb Cortex. 2023 Oct 1; 33(19): 10272–10285. Published online 2023 Aug 11. doi: 10.1093/cercor/bhad281

PMCID:: PMC10545437

Abstract Article PDF–2.8M

Select item 103491005.

Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis

Nozomu Takata, Jason M. Miska, Marc A. Morgan, Priyam Patel, Leah K. Billingham, Neha Joshi, Matthew J. Schipma, Zachary J. Dumar, Nikita R. Joshi, Alexander V. Misharin, Ryan B. Embry, Luciano Fiore, Peng Gao, Lauren P. Diebold, Gregory S. McElroy, Ali Shilatifard, Navdeep S. Chandel, Guillermo Oliver

Nat Commun. 2023; 14: 4129. Published online 2023 Jul 14. doi: 10.1038/s41467-023-39672-2

PMCID:: PMC10349100

Abstract Article PDF–7.7M

Select item 102536676.

The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer

Luis Puelles, Matias Hidalgo-Sánchez

Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769

PMCID:: PMC10253667

Abstract Article PDF–6.8M

Select item 96713687.

Cbln1 regulates axon growth and guidance in multiple neural regions

Peng Han, Yuanchu She, Zhuoxuan Yang, Mengru Zhuang, Qingjun Wang, Xiaopeng Luo, Chaoqun Yin, Junda Zhu, Samie R. Jaffrey, Sheng-Jian Ji

PLoS Biol. 2022 Nov; 20(11): e3001853. Published online 2022 Nov 17. doi: 10.1371/journal.pbio.3001853

PMCID:: PMC9671368

Abstract Article PDF–6.3M

Select item 93984538.

Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions

Miguel Ramirez, Yuliya Badayeva, Joanna Yeung, Joshua Wu, Ayasha Abdalla-Wyse, Erin Yang, FANTOM 5 Consortium, Brett Trost, Stephen W Scherer, Daniel Goldowitz

eLife. 2022; 11: e74207. Published online 2022 Aug 9. doi: 10.7554/eLife.74207

PMCID:: PMC9398453

Abstract Article PDF–5.5M

Select item 86708489.

A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia

Danielle E. Whittaker, Roberto Oleari, Louise C. Gregory, Polona Le Quesne-Stabej, Hywel J. Williams, GOSgene, John G. Torpiano, Nancy Formosa, Mario J. Cachia, Daniel Field, Antonella Lettieri, Louise A. Ocaka, Alyssa J.J. Paganoni, Sakina H. Rajabali, Kimberley L.H. Riegman, Lisa B. De Martini, Taro Chaya, Iain C.A.F. Robinson, Takahisa Furukawa, Anna Cariboni, M. Albert Basson, Mehul T. Dattani

J Clin Invest. 2021 Dec 15; 131(24): e141587. Published online 2021 Dec 15. doi: 10.1172/JCI141587

PMCID:: PMC8670848

Abstract Article PDF–19M

Select item 861252210.

A shared transcriptional code orchestrates temporal patterning of the central nervous system

Andreas Sagner, Isabel Zhang, Thomas Watson, Jorge Lazaro, Manuela Melchionda, James Briscoe

PLoS Biol. 2021 Nov; 19(11): e3001450. Published online 2021 Nov 12. doi: 10.1371/journal.pbio.3001450

PMCID:: PMC8612522

Abstract Article PDF–6.0M

Select item 828539811.

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, Tore Bleckwehl, Sara Cruz-Molina, Cally Xiao, Esther Mahabir, Hisham Bazzi, Alvaro Rada-Iglesias

Nat Commun. 2021; 12: 4344. Published online 2021 Jul 16. doi: 10.1038/s41467-021-24641-4

PMCID:: PMC8285398

Abstract Article PDF–9.7M

Select item 811714712.

Tlx3 Exerts Direct Control in Specifying Excitatory Over Inhibitory Neurons in the Dorsal Spinal Cord

Filipe A. Monteiro, Rafael M. Miranda, Marta C. Samina, Ana F. Dias, Alexandre A. S. F. Raposo, Patrícia Oliveira, Carlos Reguenga, Diogo S. Castro, Deolinda Lima

Front Cell Dev Biol. 2021; 9: 642697. Published online 2021 Apr 29. doi: 10.3389/fcell.2021.642697

PMCID:: PMC8117147

Abstract Article PDF–3.8M

Select item 807558313.

Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology

Markus Terrey, Scott I Adamson, Jeffrey H Chuang, Susan L Ackerman

eLife. 2021; 10: e66904. Published online 2021 Apr 26. doi: 10.7554/eLife.66904

PMCID:: PMC8075583

Abstract Article PDF–8.4M

Select item 807558214.

MicroRNAs mediate precise control of spinal interneuron populations to exert delicate sensory-to-motor outputs

Shih-Hsin Chang, Yi-Ching Su, Mien Chang, Jun-An Chen

eLife. 2021; 10: e63768. Published online 2021 Mar 31. doi: 10.7554/eLife.63768

PMCID:: PMC8075582

Abstract Article PDF–5.5M

Select item 801220715.

Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia

Ugomma C. Eze, Aparna Bhaduri, Maximilian Haeussler, Tomasz J. Nowakowski, Arnold R. Kriegstein

Nat Neurosci. 2021; 24(4): 584–594. Published online 2021 Mar 15. doi: 10.1038/s41593-020-00794-1

PMCID:: PMC8012207

Abstract Article PDF–7.5M

Select item 799017916.

Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons

Jia Li, Lei Sun, Xue-Liang Peng, Xiao-Ming Yu, Shao-Jun Qi, Zhi John Lu, Jing-Dong J. Han, Qin Shen

PLoS Genet. 2021 Mar; 17(3): e1009355. Published online 2021 Mar 24. doi: 10.1371/journal.pgen.1009355

PMCID:: PMC7990179

Abstract Article PDF–3.3M

Select item 793877017.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003