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Select item 108306551.

Knockout of KDM3A in MDA-MB-231 breast cancer cells inhibits tumor malignancy and promotes apoptosis

Yuanxing Han, Nueryemu Maimaiti, Yue Sun, Juan Yao

J Mol Histol. 2024; 55(1): 139–148. Published online 2024 Jan 2. doi: 10.1007/s10735-023-10178-x

PMCID:: PMC10830655

Abstract Article PDF–4.0M

Select item 106277862.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 105658763.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 101826544.

The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase

Eva Monte-Serrano, Patricia Morejón-García, Ignacio Campillo-Marcos, Aurora Campos-Díaz, Elena Navarro-Carrasco, Pedro A. Lazo

Epigenetics Chromatin. 2023; 16: 18. Published online 2023 May 13. doi: 10.1186/s13072-023-00494-7

PMCID:: PMC10182654

Abstract Article PDF–3.1M

Select item 97696985.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 95403456.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 93485767.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 91536928.

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4

Ashish Kumar, Yuanzhi Lyu, Yuichi Yanagihashi, Chanikarn Chantarasrivong, Vladimir Majerciak, Michelle Salemi, Kang-Hsin Wang, Tomoki Inagaki, Frank Chuang, Ryan R. Davis, Clifford G. Tepper, Kazushi Nakano, Chie Izumiya, Michiko Shimoda, Ken-ichi Nakajima, Alexander Merleev, Zhi-Ming Zheng, Mel Campbell, Yoshihiro Izumiya

Cell Rep. Author manuscript; available in PMC 2022 May 31.

Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110788. doi: 10.1016/j.celrep.2022.110788

PMCID:: PMC9153692

Abstract Article PDF–3.0M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 911393710.

Downregulation of miR-335 exhibited an oncogenic effect via promoting KDM3A/YAP1 networks in clear cell renal cell carcinoma

Wenqiang Zhang, Ruiyu Liu, Lin Zhang, Chao Wang, Ziyan Dong, Jiasheng Feng, Mayao Luo, Yifan Zhang, Zhuofan Xu, Shidong Lv, Qiang Wei

Cancer Gene Ther. 2022; 29(5): 573–584. Published online 2021 Apr 23. doi: 10.1038/s41417-021-00335-3

PMCID:: PMC9113937

Abstract Article PDF–3.7M

Select item 910523511.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 893052712.

Histone demethylase JMJD1A in cancer progression and therapeutic resistance

Hee-Young Jeon, Hyunju Ryu, Majid Pornour, Jianfei Qi

Mol Carcinog. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Mol Carcinog. 2022 Apr; 61(4): 392–396. Published online 2022 Jan 12. doi: 10.1002/mc.23390

PMCID:: PMC8930527

Abstract Article PDF–301K

Select item 860245113.

Identification of proximal SUMO-dependent interactors using SUMO-ID

Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland

Nat Commun. 2021; 12: 6671. Published online 2021 Nov 18. doi: 10.1038/s41467-021-26807-6

PMCID:: PMC8602451

Abstract Article PDF–11M

Select item 852269014.

KDM3A regulates alternative splicing of cell-cycle genes following DNA damage

Mai Baker, Mayra Petasny, Nadeen Taqatqa, Mercedes Bentata, Gillian Kay, Eden Engal, Yuval Nevo, Ahmad Siam, Sara Dahan, Maayan Salton

RNA. 2021 Nov; 27(11): 1353–1362. doi: 10.1261/rna.078796.121

PMCID:: PMC8522690

Abstract Article PDF–1.3M

Select item 842463415.

KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer

Xuyang Hou, Qiuguo Li, Leping Yang, Zhulin Yang, Jun He, Qinglong Li, Daming Li

Exp Biol Med (Maywood) 2021 Sep; 246(17): 1869–1883. Published online 2021 Jun 25. doi: 10.1177/15353702211023473

PMCID:: PMC8424634

Abstract Article PDF–2.3M

Select item 841919416.

Overexpression of let‐7d explains down‐regulated KDM3A and ENO2 in the pathogenesis of preeclampsia

Qian Xu, Yonghui Song, Lili Lu

J Cell Mol Med. 2021 Sep; 25(17): 8127–8139. Published online 2021 Aug 5. doi: 10.1111/jcmm.16299

PMCID:: PMC8419194

Abstract Article PDF–1.0M

Select item 841468817.

HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury

Min Zhao, Shaoting Wang, Anna Zuo, Jiaxing Zhang, Weiheng Wen, Weiqiang Jiang, Hong Chen, Donghui Liang, Jia Sun, Ming Wang

Cell Mol Biol Lett. 2021; 26: 40. Published online 2021 Sep 3. doi: 10.1186/s11658-021-00283-8

PMCID:: PMC8414688

Abstract Article PDF–4.0M

Select item 822039118.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Abstract Article PDF–4.4M

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 773688320.

JmjC-KDMs KDM3A and KDM6B modulate radioresistance under hypoxic conditions in esophageal squamous cell carcinoma

Catarina Macedo-Silva, Vera Miranda-Gonçalves, Ana Lameirinhas, Joana Lencart, Alexandre Pereira, João Lobo, Rita Guimarães, Ana Teresa Martins, Rui Henrique, Isabel Bravo, Carmen Jerónimo

Cell Death Dis. 2020 Dec; 11(12): 1068. Published online 2020 Dec 14. doi: 10.1038/s41419-020-03279-y

PMCID:: PMC7736883

Abstract Article PDF–2.9M

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