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Items: 1 to 20 of 37

1.
A therapeutically targetable TAZ-TEAD2 pathway drives the growth of hepatocellular carcinoma via ANLN and KIF23
Yoshinobu Saito, Dingzi Yin, Naoto Kubota, Xiaobo Wang, Aveline Filliol, Helen Remotti, Ajay Nair, Ladan Fazlollahi, Yujin Hoshida, Ira Tabas, Kirk J. Wangensteen, Robert F. Schwabe
Gastroenterology. Author manuscript; available in PMC 2024 Jun 1.
Published in final edited form as: Gastroenterology. 2023 Jun; 164(7): 1279–1292. Published online 2023 Mar 7. doi: 10.1053/j.gastro.2023.02.043
PMCID:
PMC10335360
AbstractArticlePDF–3.0M
2.
A TEAD2-driven endothelial-like program shapes basal-like differentiation and metastasis of pancreatic cancer
Hye-Been Yoo, Jin Woo Moon, Hwa-Ryeon Kim, Hee Seung Lee, Koji Miyabayashi, Chan Hee Park, Sabrina Ge, Amy Zhang, Yoo Keung Tae, Yujin Sub, Hyun-Woo Park, Heon Yung Gee, Faiyaz Notta, David A. Tuveson, Seungmin Bang, Mi-Young Kim, Jae-Seok Roe
Gastroenterology. Author manuscript; available in PMC 2023 Jul 10.
Published in final edited form as: Gastroenterology. 2023 Jul; 165(1): 133–148.e17. Published online 2023 Mar 11. doi: 10.1053/j.gastro.2023.02.049
PMCID:
PMC10330865
AbstractArticlePDF–2.8M
3.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
4.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
5.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
8.
Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation
Danielle G. May, Kelsey L. Scott, Alexandre R. Campos, Kyle J. Roux
Cells. 2020 May; 9(5): 1070. Published online 2020 Apr 25. doi: 10.3390/cells9051070
PMCID:
PMC7290721
AbstractArticlePDF–9.2M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
TEAD2 as a novel prognostic factor for hepatocellular carcinoma
Jong Seok Joo, Sang Yeon Cho, Woo Sun Rou, Ju Seok Kim, Sun Hyung Kang, Eaum Seok Lee, Hee Seok Moon, Seok Hyun Kim, Jae Kyu Sung, In Sun Kwon, Hyuk Soo Eun, Byung Seok Lee
Oncol Rep. 2020 Jun; 43(6): 1785–1796. Published online 2020 Apr 6. doi: 10.3892/or.2020.7578
PMCID:
PMC7160555
AbstractArticlePDF–4.4M
11.
MicroRNA-608 sensitizes non-small cell lung cancer cells to cisplatin by targeting TEAD2
Yanli Wang, Fengcai Li, Dandan Ma, Yuhua Gao, Runpu Li, Yingjie Gao
Mol Med Rep. 2019 Oct; 20(4): 3519–3526. Published online 2019 Aug 26. doi: 10.3892/mmr.2019.10616
PMCID:
PMC6755186
AbstractArticlePDF–896K
12.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
13.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
14.
The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies
Zenggang Li, Andrei A. Ivanov, Rina Su, Valentina Gonzalez-Pecchi, Qi Qi, Songlin Liu, Philip Webber, Elizabeth McMillan, Lauren Rusnak, Cau Pham, Xiaoqian Chen, Xiulei Mo, Brian Revennaugh, Wei Zhou, Adam Marcus, Sahar Harati, Xiang Chen, Margaret A. Johns, Michael A. White, Carlos S. Moreno, Lee A. D. Cooper, Yuhong Du, Fadlo R. Khuri, Haian Fu
Nat Commun. 2017; 8: 14356. Published online 2017 Feb 16. doi: 10.1038/ncomms14356
Correction in:
Nat Commun. 2017; 8: 15350.
PMCID:
PMC5316855
AbstractArticlePDF–4.1M
15.
Enabling systematic interrogation of protein–protein interactions in live cells with a versatile ultra-high-throughput biosensor platform
Xiu-Lei Mo, Yin Luo, Andrei A. Ivanov, Rina Su, Jonathan J. Havel, Zenggang Li, Fadlo R. Khuri, Yuhong Du, Haian Fu
J Mol Cell Biol. 2016 Jun; 8(3): 271–281. Published online 2016 Jul 7. doi: 10.1093/jmcb/mjv064
PMCID:
PMC4937889
AbstractArticlePDF–6.5M
16.
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics
Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth
Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660
PMCID:
PMC4848762
AbstractArticlePDF–2.8M
17.
The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis
Giorgio Oliviero, Nayla Munawar, Ariane Watson, Gundula Streubel, Gwendolyn Manning, Vivian Bardwell, Adrian P. Bracken, Gerard Cagney
Sci Rep. 2015; 5: 18388. Published online 2015 Dec 21. doi: 10.1038/srep18388
PMCID:
PMC4685312
AbstractArticlePDF–1.5M
18.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
19.
Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor
Ivette Valencia-Sama, Yulei Zhao, Dulcie Lai, Helena J. Janse van Rensburg, Yawei Hao, Xiaolong Yang
J Biol Chem. 2015 Jul 3; 290(27): 16906–16917. Published online 2015 May 20. doi: 10.1074/jbc.M115.642363
PMCID:
PMC4505436
AbstractArticlePDF–2.9M
20.
LATS2-mediated YAP1 phosphorylation is involved in HCC tumorigenesis
Chao Guo, Xintian Wang, Lufeng Liang
Int J Clin Exp Pathol. 2015; 8(2): 1690–1697. Published online 2015 Feb 1.
PMCID:
PMC4396227
AbstractArticlePDF–1.2M

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